This webpage contains legacy information. The product is either no longer available from the supplier or has been delisted at Labome.
product summary
company name :
MyBioSource
product type :
antibody
product name :
Rabbit Polyclonal to Human HTR2A / 5-HT2A Receptor
catalog :
MBS242390
quantity :
0.05 mg
price :
495 USD
clonality :
polyclonal
host :
rabbit
conjugate :
nonconjugated
reactivity :
human, dog, cow, chimpanzee
application :
immunohistochemistry, immunohistochemistry - paraffin section
product information
catalog number :
MBS242390
products type :
Antibody
products full name :
Rabbit Polyclonal to Human HTR2A / 5-HT2A Receptor
products short name :
HTR2A / 5-HT2A Receptor
products name syn :
Anti-HTR2A / 5-HT2A Receptor Antibody (N-Terminus) IHC-plus; HTR2A; 5-HT2A; 5-HT-2A; 5-HT2a receptor; 5HT2A Receptor; 5-HT-2; 5-HT2A/2C; 5-HT2A/2C receptor; 5-HT2 receptor; HTR2; Serotonin 5-HT-2A receptor; Serotonin receptor 2A; Serotonin 2a receptor; Human HTR2A; 5-HT2A Receptor
other names :
5-hydroxytryptamine receptor 2A isoform 1; 5-hydroxytryptamine receptor 2A; 5-hydroxytryptamine receptor 2A; 5-HT-2A; 5-HT2 receptor; serotonin 5-HT-2A receptor; 5-hydroxytryptamine (serotonin) receptor 2A, G protein-coupled; Serotonin receptor 2A
products gene name :
HTR2A
other gene names :
HTR2A; HTR2A; HTR2; 5-HT2A; HTR2; 5-HT-2; 5-HT-2A
uniprot entry name :
5HT2A_HUMAN
clonality :
Polyclonal
host :
Rabbit
reactivity :
Bat, Gibbon, Chimpanzee, Gorilla, Horse, Human, Orangutan, Pig. Predicted Reactivity: Monkey, Bovine, Dog (at least 90% immunogen sequence identity)
sequence length :
471
specificity :
Human 5HT2A Receptor. BLAST analysis of the peptide immunogen showed no homology with other human proteins.
purity :
Immunoaffinity Purified
form :
PBS, 0.1% sodium azide.
concentration :
1 mg/ml
storage stability :
Short term: +4 degree C. Long term: aliquot and store at -70 degree C.
tested application :
Immunohistochemistry (IHC - Paraffin)
app notes :
IHC-P (10 - 12.5 ug/ml). Usage: Immunohistochemistry with formalin-fixed paraffin-embedded tissues requires pretreatment with Proteinase K.
other info1 :
Target Species: Human. Immunogen Description: Synthetic 17 amino acid peptide from N-Terminus of human 5HT2A Receptor. Percent identity with other species by BLAST analysis: Human, Chimpanzee, Gorilla, Orangutan, Gibbon, Monkey, Panda, Horse, Pig, Bat, Elephant (100%); Marmoset, Bovine, Dog (94%)
other info2 :
Immunogen Type: Synthetic peptide. Immunogen: HTR2A / 5-HT2A Receptor antibody was raised against synthetic 17 amino acid peptide from N-Terminus of human 5HT2A Receptor. Percent identity with other species by BLAST analysis: Human, Chimpanzee, Gorilla, Orangutan, Gibbon, Monkey, Panda, Horse, Pig, Bat, Elephant (100%); Marmoset, Bovine, Dog (94%); Hamster (82%). Antigen Modification: N-Terminus
products categories :
Family: GPCR. Subfamily: Serotonin
products description :
The 5-HT2A Receptor is a member of the Serotonin Receptor subfamily. 5-HT2A polymorphisms have been associated with schizophrenia and psychotic symptoms in Alzheimer's disease.
ncbi gi num :
10835175
ncbi acc num :
NP_000612.1
ncbi gb acc num :
NM_000621.4
uniprot acc num :
P28223
ncbi mol weight :
43,940 Da
ncbi pathways :
Amine Ligand-binding Receptors Pathway 106363!!Calcium Signaling Pathway 83050!!Calcium Signaling Pathway 459!!Class A/1 (Rhodopsin-like Receptors) Pathway 106357!!Defective ACTH Causes Obesity And Pro-opiomelanocortinin Deficiency (POMCD) Pathway 1127664!!Disease Pathway 530764!!G Alpha (q) Signalling Events Pathway 106043!!GPCR Downstream Signaling Pathway 119548!!GPCR Ligand Binding Pathway 161020!!GPCRs, Class A Rhodopsin-like Pathway 198886
ncbi summary :
This gene encodes one of the receptors for serotonin, a neurotransmitter with many roles. Mutations in this gene are associated with susceptibility to schizophrenia and obsessive-compulsive disorder, and are also associated with response to the antidepressant citalopram in patients with major depressive disorder (MDD). MDD patients who also have a mutation in intron 2 of this gene show a significantly reduced response to citalopram as this antidepressant downregulates expression of this gene. Multiple transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Sep 2009]
size :
0.05 mg
price :
495 USD
company information
MyBioSource
P.O. Box 153308
San Diego, CA 92195-3308
sales@mybiosource.com
https://www.mybiosource.com
1-888-627-0165
headquarters: USA
MyBioSource, LLC was orginally founded in Vancouver by three enthusiastic scientists who are passionate about providing the world with the best reagents available. Together, they form a company with a big vision known as MyBioSource. MyBioSource is now located in San Diego, California, USA.

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