catalog number :
MBS242332
products full name :
Rabbit Polyclonal to Human HSP27 / Heat Shock Protein 27
products short name :
HSP27 / Heat Shock Protein 27
products name syn :
Anti-HSP27 / Heat Shock Protein 27 Antibody IHC-plus; Heat Shock Protein 27; Human HSP27; Heat Shock Protein 27
other names :
HSP27; Heat shock protein beta-1; heat shock protein beta-1; HSP 27; 28 kDa heat shock protein; heat shock 27 kDa protein; heat shock 27kD protein 1; stress-responsive protein 27; estrogen-regulated 24 kDa protein; epididymis secretory protein Li 102; heat shock 27kDa protein 1; 28 kDa heat shock protein; Estrogen-regulated 24 kDa protein; Heat shock 27 kDa protein; HSP 27; Stress-responsive protein 27; SRP27
products gene name :
HSP27
other gene names :
HSPB1; HSPB1; CMT2F; HMN2B; HSP27; HSP28; Hsp25; SRP27; HS.76067; HEL-S-102; HSP27; HSP28; HspB1; HSP 27; SRP27
uniprot entry name :
HSPB1_HUMAN
reactivity :
Human, Monkey
purity :
Protein A Purified
form :
PBS, 0.09% azide, 50% glycerol
storage stability :
Store at -20 degree C. Aliquot to avoid freeze/thaw cycles.
tested application :
Immunohistochemistry (IHC - Paraffin), Western Blot (WB), Immunoprecipitation (IP)
app notes :
IHC-P (10 ug/ml), IP (10 ug/ml), WB (1:11000). Usage: Immunohistochemistry: was validated for use in immunohistochemistry on a panel of 21 formalin-fixed, paraffin-embedded (FFPE) human tissues after heat induced antigen retrieval in pH 6.0 citrate buffer. After incubation with the primary anti.
other info1 :
Target Species: Human. Immunogen Description: Recombinant human Hsp27 protein.
other info2 :
Immunogen Type: Recombinant protein. Immunogen: Recombinant human Hsp27 protein.
ncbi acc num :
BAB17232.1
ncbi mol weight :
22,783 Da
ncbi pathways :
AUF1 (hnRNP D0) Destabilizes MRNA Pathway 187212!!Amoebiasis Pathway 167324!!Amoebiasis Pathway 167191!!Epstein-Barr Virus Infection Pathway 585562!!Epstein-Barr Virus Infection Pathway 587115!!FAS Pathway And Stress Induction Of HSP Regulation 198894!!Gene Expression Pathway 105937!!IL-3 Signaling Pathway 198881!!IL-6 Signaling Pathway 198864!!MAPK Signaling Pathway 198779
ncbi summary :
The protein encoded by this gene is induced by environmental stress and developmental changes. The encoded protein is involved in stress resistance and actin organization and translocates from the cytoplasm to the nucleus upon stress induction. Defects in this gene are a cause of Charcot-Marie-Tooth disease type 2F (CMT2F) and distal hereditary motor neuropathy (dHMN). [provided by RefSeq, Oct 2008]