Goat Polyclonal to Human AOC3 / VAP-1 | MyBioSource MBS242214 product information

product summary

company name :

MyBioSource

product type :

antibody

product name :

Goat Polyclonal to Human AOC3 / VAP-1

catalog :

MBS242214

quantity :

0.05 mg

price :

495 USD

clonality :

polyclonal

host :

goat

conjugate :

nonconjugated

reactivity :

human, mouse, rat

application :

ELISA, immunohistochemistry, enzyme immunoassay

more info or order :

MyBioSource product webpage

product information

catalog number :

MBS242214

products type :

Antibody

products full name :

Goat Polyclonal to Human AOC3 / VAP-1

products short name :

AOC3 / VAP-1

products name syn :

Anti-AOC3 / VAP-1 Antibody (Internal) IHC-plus; AOC3; Copper amine oxidase; HPAO; Membrane primary amine oxidase; SSAO; VAP-1; VAP1; Vascular adhesion protein 1; Human AOC3; VAP-1

other names :

membrane primary amine oxidase isoform 1; Membrane primary amine oxidase; membrane primary amine oxidase; copper amine oxidase; placenta copper monamine oxidase; semicarbazide-sensitive amine oxidase; amine oxidase, copper containing 3 (vascular adhesion protein 1); amine oxidase, copper containing 3; Copper amine oxidase; HPAO; Semicarbazide-sensitive amine oxidase; SSAO; Vascular adhesion protein 1; VAP-1

products gene name :

AOC3

products gene name syn :

VAP-1

other gene names :

AOC3; AOC3; HPAO; SSAO; VAP1; VAP-1; VAP1; SSAO; VAP-1

uniprot entry name :

AOC3_HUMAN

clonality :

Polyclonal

host :

Goat

reactivity :

Human, Hamster. Predicted Reactivity: Monkey, Mouse, Rat, Rabbit

sequence length :

763

specificity :

Human AOC3 / VAP-1.

purity :

Immunoaffinity Purified

form :

Tris-buffered saline, pH 7.3, 0.5% BSA, 0.02% sodium azide

concentration :

0.5 mg/ml

storage stability :

Store at -20 degree C. Minimize freezing and thawing.

tested application :

Immunohistochemistry (IHC - Paraffin), ELISA (EIA)

app notes :

ELISA (1:64000), IHC-P (3.75 ug/ml). Usage: Immunohistochemistry: was validated for use in immunohistochemistry on a panel of 21 formalin-fixed, paraffin-embedded (FFPE) human tissues after heat induced antigen retrieval in pH 6.0 citrate buffer. After incubation with the primary antibody, slides were incubated with biotinylated secondary antibody, followed by alkaline phosphatase-streptavidin and chromogen. The stained slides were evaluated by a pathologist to confirm staining specificity. The optimal working concentration for MBS242214 was determined to be 3.75ug/ml

other info1 :

Target Species: Human. Target: AOC3/VAP-1. Immunogen Description: Synthetic peptide C-DEDPSFYSADSIY from an internal region (near the C-terminus) of human AOC3 / VAP-1 (NP_003725.1). Percent identity by BLAST analysis: Human, Gorilla, Orangutan, Marmoset, Hamster (100%); Gibbon, Monkey, Mouse, Rat, Rabbit (92%). Antigen Type: Synthetic peptide

other info2 :

Immunogen: AOC3 / VAP-1 antibody was raised against synthetic peptide C-DEDPSFYSADSIY from an internal region (near the C-terminus) of human AOC3 / VAP-1 (NP_003725.1). Percent identity by BLAST analysis: Human, Gorilla, Orangutan, Marmoset, Hamster (100%); Gibbon, Monkey, Mouse, Rat, Rabbit (92%); Elephant, Bovine (85%). Antigen Modification: Internal

ncbi gi num :

4502119

ncbi acc num :

NP_003725.1

ncbi gb acc num :

NM_003734.3

uniprot acc num :

Q16853

ncbi mol weight :

24,533 Da

ncbi pathways :

Glycine, Serine And Threonine Metabolism Pathway (82949); Glycine, Serine And Threonine Metabolism Pathway (313); Metabolic Pathways (132956); Phenylalanine Metabolism Pathway (82960); Phenylalanine Metabolism Pathway (327); Tyrosine Metabolism Pathway (82959); Tyrosine Metabolism Pathway (325); Beta-Alanine Metabolism Pathway (82966); Beta-Alanine Metabolism Pathway (335); Phenylethylamine Degradation I Pathway (547500)

ncbi summary :

This gene encodes a member of the semicarbazide-sensitive amine oxidase family. Copper amine oxidases catalyze the oxidative conversion of amines to aldehydes in the presence of copper and quinone cofactor. The encoded protein is localized to the cell surface, has adhesive properties as well as monoamine oxidase activity, and may be involved in leukocyte trafficking. Alterations in levels of the encoded protein may be associated with many diseases, including diabetes mellitus. A pseudogene of this gene has been described and is located approximately 9-kb downstream on the same chromosome. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Apr 2013]

uniprot summary :

AOC3: Cell adhesion protein that participates in lymphocyte recirculation by mediating the binding of lymphocytes to peripheral lymph node vascular endothelial cells in an L-selectin- independent fashion. Has a monoamine oxidase activity. May play a role in adipogenesis. Belongs to the copper/topaquinone oxidase family. Protein type: Oxidoreductase; Cell adhesion; Amino Acid Metabolism - tyrosine; Amino Acid Metabolism - glycine, serine and threonine; Amino Acid Metabolism - phenylalanine; Other Amino Acids Metabolism - beta-alanine; EC 1.4.3.21; Membrane protein, integral. Chromosomal Location of Human Ortholog: 17q21. Cellular Component: microvillus; cell surface; cytoplasm; plasma membrane; integral to membrane. Molecular Function: amine oxidase activity; protein binding; protein homodimerization activity; copper ion binding; protein heterodimerization activity; cation channel activity; calcium ion binding; quinone binding. Biological Process: response to antibiotic; amine metabolic process; cell adhesion; inflammatory response; cation transport

size1 :

0.05 mg

price1 :

495 USD

more info or order :

MyBioSource product webpage