catalog number :
MBS242196
products full name :
Goat Polyclonal to Human AKR1A1
products short name :
AKR1A1
products name syn :
Anti-AKR1A1 Antibody (C-Terminus) IHC-plus; AKR1A1; ALDR1; Aldehyde reductase; Alcohol dehydrogenase; ARM; DD3; Dihydrodiol dehydrogenase 3; ALR; Human AKR1A1
other names :
alcohol dehydrogenase; Alcohol dehydrogenase [NADP(+)]; alcohol dehydrogenase [NADP(+)]; alcohol dehydrogenase [NADP(+)]; HEL-S-165mP; aldehyde reductase; dihydrodiol dehydrogenase 3; epididymis secretory protein Li 6; aldo-keto reductase family 1 member A1; epididymis secretory sperm binding protein Li 165mP; aldo-keto reductase family 1, member A1 (aldehyde reductase); Aldehyde reductase; Aldo-keto reductase family 1 member A1
products gene name :
AKR1A1
other gene names :
AKR1A1; AKR1A1; ALR; ARM; DD3; ALDR1; HEL-S-6; ALDR1; ALR
uniprot entry name :
AK1A1_HUMAN
reactivity :
Bat, Gibbon, Bovine, Dog, Xenopus, Gorilla, Hamster, Horse, Human, Monkey, Mouse, Orangutan, Pig, Rabbit, Rat. Predicted Reactivity: Chicken, Zebrafish (at least 90% immunogen sequence identity)
specificity :
Human AKR1A1. Both reported variants (NP_006057.1and NP_697021.1) represent identical protein
purity :
Immunoaffinity Purified
form :
Tris-buffered saline, pH 7.3, 0.5% BSA, 0.02% sodium azide
concentration :
0.5 mg/ml
storage stability :
Store at -20 degree C. Minimize freezing and thawing.
tested application :
Immunohistochemistry (IHC - Paraffin), Western Blot (WB), ELISA (EIA)
app notes :
ELISA (1:16000), IHC-P (2.5 ug/ml), WB (0.5 - 2 ug/ml). Usage: Immunohistochemistry: was validated for use in immunohistochemistry on a panel of 21 formalin-fixed, paraffin-embedded (FFPE) human tissues after heat induced antigen retrieval in pH 6.0 citrate buffer. After incubation with the primary anti.
other info1 :
Target Species: Human. Immunogen Description: Synthetic peptide C-DAGHPLYPFNDPY from the C-terminus of human AKR1A1 (NP_006057.1; NP_697021.1).
other info2 :
Immunogen Type: Synthetic peptide. Immunogen: AKR1A1 antibody was raised against synthetic peptide C-DAGHPLYPFNDPY from the C-terminus of human AKR1A1 (NP_006057.1; NP_697021.1). Percent identity by BLAST analysis: Human, Gorilla, Orangutan, Gibbon, Marmoset, Mouse, Rat, Hamster, Elephant, Dog, Bat, Bovine, Horse, Rabbit, Pig, Xenopus (100%); Turkey, Chicken, Platypus, Catfish, Zebrafish (92%); Opossum, Salmon, Stickleback, Pike (85%). Antigen Modification: C-Terminus
products description :
This gene encodes a member of the aldo/keto reductase superfamily, which consists of more than 40 known enzymes and proteins. This member, also known as aldehyde reductase, is involved in the reduction of biogenic and xenobiotic aldehydes and is present in virtually every tissue. Alternative splicing of this gene results in two transcript variants encoding the same protein.
ncbi acc num :
NP_006057.1
ncbi gb acc num :
NM_006066.3
ncbi mol weight :
36,573 Da
ncbi pathways :
Benzo(a)pyrene Metabolism Pathway 198911!!Degradation Of Aromatic Compounds Pathway 843021!!Degradation Of Aromatic Compounds Pathway 717401!!Glucuronate Pathway (uronate Pathway) 997799!!Glucuronate Pathway (uronate Pathway) 468207!!Glycerolipid Metabolism Pathway 82986!!Glycerolipid Metabolism Pathway 361!!Glycolysis / Gluconeogenesis Pathway 82926!!Glycolysis / Gluconeogenesis Pathway 287!!Metabolic Pathways 132956
ncbi summary :
This gene encodes a member of the aldo/keto reductase superfamily, which consists of more than 40 known enzymes and proteins. This member, also known as aldehyde reductase, is involved in the reduction of biogenic and xenobiotic aldehydes and is present in virtually every tissue. Multiple alternatively spliced transcript variants of this gene exist, all encoding the same protein. [provided by RefSeq, Jan 2011]