catalog number :
MBS242119
products full name :
Goat Polyclonal to Human MIF
products short name :
MIF
products name syn :
Anti-MIF Antibody (C-Terminus) IHC-plus; MIF; GLIF; L-dopachrome tautomerase; L-dopachrome isomerase; MMIF; Phenylpyruvate tautomerase; Human MIF
other names :
macrophage migration inhibitory factor; Macrophage migration inhibitory factor; macrophage migration inhibitory factor; L-dopachrome isomerase; L-dopachrome tautomerase; phenylpyruvate tautomerase; macrophage migration inhibitory factor (glycosylation-inhibiting factor); Glycosylation-inhibiting factor; GIF; L-dopachrome isomerase; L-dopachrome tautomerase (EC:5.3.3.12); Phenylpyruvate tautomerase
other gene names :
MIF; MIF; GIF; GLIF; MMIF; GLIF; MMIF; MIF; GIF
uniprot entry name :
MIF_HUMAN
reactivity :
Gibbon, Gorilla, Human, Monkey. Predicted Reactivity: Mouse, Rat, Bovine, Horse, Pig, Rabbit, Sheep, Chicken, Xenopus (at least 90% immunogen sequence identity)
purity :
Immunoaffinity Purified
form :
Tris-buffered saline, pH 7.3, 0.5% BSA, 0.02% sodium azide
concentration :
0.5 mg/ml
storage stability :
Store at -20 degree C. Minimize freezing and thawing.
tested application :
Immunohistochemistry (IHC - Paraffin), Western Blot (WB), ELISA (EIA)
app notes :
ELISA (1:128000), IHC-P (2.5 ug/ml), WB (0.01 - 0.03 ug/ml). Usage: Immunohistochemistry: was validated for use in immunohistochemistry on a panel of 21 formalin-fixed, paraffin-embedded (FFPE) human tissues after heat induced antigen retrieval in pH 6.0 citrate buffer. After incubation with the primary anti.
other info1 :
Target Species: Human. Immunogen Description: Synthetic peptide C-NAANVGWNNSTFA from the C-terminus of human MIF (NP_002406.1).
other info2 :
Immunogen Type: Synthetic peptide. Immunogen: MIF antibody was raised against synthetic peptide C-NAANVGWNNSTFA from the C-terminus of human MIF (NP_002406.1). Percent identity by BLAST analysis: Human, Gorilla, Gibbon, Monkey (100%); Mouse, Rat, Sheep, Elephant, Bovine, Horse, Rabbit, Pig, Turkey, Chicken, Platypus, Xenopus (92%); Hamster (85%). Antigen Modification: C-Terminus
ncbi acc num :
NP_002406.1
ncbi gb acc num :
NM_002415.1
ncbi mol weight :
12,476 Da
ncbi pathways :
Adipogenesis Pathway 198832!!Phenylalanine Metabolism Pathway 82960!!Phenylalanine Metabolism Pathway 327!!Spinal Cord Injury Pathway 739007!!Tyrosine Metabolism Pathway 82959!!Tyrosine Metabolism Pathway 325
ncbi summary :
This gene encodes a lymphokine involved in cell-mediated immunity, immunoregulation, and inflammation. It plays a role in the regulation of macrophage function in host defense through the suppression of anti-inflammatory effects of glucocorticoids. This lymphokine and the JAB1 protein form a complex in the cytosol near the peripheral plasma membrane, which may indicate an additional role in integrin signaling pathways. [provided by RefSeq, Jul 2008]