catalog number :
MBS242093
products full name :
Rabbit Polyclonal (IgG) to Human S100A4 / FSP1
products short name :
S100A4 / FSP1
products name syn :
Anti-S100A4 / FSP1 Antibody IHC-plus; S100A4; 42A; 18A2; Fibroblast-specific protein-1; FSP1; MTS1; PEL98; Protein Mts1; Calvasculin; CAPL; Metastasin; p9KA; Protein S100-A4; Human S100A4; FSP1
other names :
protein S100-A4; Protein S100-A4; protein S100-A4; protein Mts1; fibroblast-specific protein-1; placental calcium-binding protein; malignant transformation suppression 1; leukemia multidrug resistance associated protein; S100 calcium-binding protein A4 (calcium protein, calvasculin, metastasin, murine placental homolog); S100 calcium binding protein A4; Calvasculin; Metastasin; Placental calcium-binding protein; Protein Mts1; S100 calcium-binding protein A4
products gene name :
S100A4
products gene name syn :
FSP1
other gene names :
S100A4; S100A4; 42A; 18A2; CAPL; FSP1; MTS1; P9KA; PEL98; CAPL; MTS1
uniprot entry name :
S10A4_HUMAN
specificity :
Recognizes human S100A4.
purity :
Immunoaffinity Purified
form :
10 mM PBS, pH 7.6, 0.2% BSA, 15 mM sodium azide.
concentration :
0.2 mg/ml
storage stability :
Long term: -20 degree C; Short term: +4 degree C. Avoid repeat freeze-thaw cycles.
tested application :
Immunohistochemistry (IHC - Paraffin)
app notes :
IHC-P (2.5 ug/ml). Usage: Immunohistochemistry: was validated for use in immunohistochemistry on a panel of 21 formalin-fixed, paraffin-embedded (FFPE) human tissues after heat induced antigen retrieval in pH 6.0 citrate buffer. After incubation with the primary anti.
other info1 :
Target Species: Human. Immunogen Description: Recombinant protein encoding full length human S100A4Cellular Localization: Cytoplasmic. MW of Antigen: 10-12kD.
other info2 :
Immunogen Type: Recombinant protein. Immunogen: S100A4 / FSP1 antibody was raised against recombinant protein encoding full length human S100A4Cellular Localization: Cytoplasmic. MW of Antigen: 10-12kD.
products description :
S100 Calcium Binding Protein A4 (S100A4) is a member of the S100 family of proteins containing 2 EF-hand calcium-binding motifs. S100 proteins are localized in the cytoplasm and/or nucleus of a wide range of cells, and involved in the regulation of a number of cellular processes such as cell cycle progression and differentiation. S100 genes include at least 13 members which are located as a cluster on chromosome 1q21. S100A4 may function in motility, invasion, and tubulin polymerization.
ncbi acc num :
NP_062427.1
ncbi gb acc num :
NM_019554.2
ncbi mol weight :
11,729 Da
ncbi summary :
The protein encoded by this gene is a member of the S100 family of proteins containing 2 EF-hand calcium-binding motifs. S100 proteins are localized in the cytoplasm and/or nucleus of a wide range of cells, and involved in the regulation of a number of cellular processes such as cell cycle progression and differentiation. S100 genes include at least 13 members which are located as a cluster on chromosome 1q21. This protein may function in motility, invasion, and tubulin polymerization. Chromosomal rearrangements and altered expression of this gene have been implicated in tumor metastasis. Multiple alternatively spliced variants, encoding the same protein, have been identified. [provided by RefSeq, Jul 2008]
uniprot summary :
S100A4: is a member of the S100 family of proteins containing 2 EF-hand calcium-binding motifs. S100 proteins are localized in the cytoplasm and/or nucleus of a wide range of cells, and involved in the regulation of a number of cellular processes such as cell cycle progression and differentiation. S100 genes include at least 13 members which are located as a cluster on chromosome 1q21. This protein may function in motility, invasion, and tubulin polymerization. Chromosomal rearrangements and altered expression of this gene have been implicated in tumor metastasis. Multiple alternatively spliced variants, encoding the same protein, have been identified. [provided by RefSeq, Jul 2008]. Protein type: Motility/polarity/chemotaxis. Chromosomal Location of Human Ortholog: 1q21. Cellular Component: extracellular space; neuron projection; perinuclear region of cytoplasm; nucleus. Molecular Function: identical protein binding; RAGE receptor binding; protein binding; calcium ion binding; actin binding; calcium-dependent protein binding. Biological Process: positive regulation of I-kappaB kinase/NF-kappaB cascade; epithelial to mesenchymal transition