catalog number :
MBS242067
products full name :
Goat Polyclonal to Human Kinesin Heavy Chain / KIF5B
products short name :
Kinesin Heavy Chain / KIF5B
products name syn :
Anti-Kinesin Heavy Chain / KIF5B Antibody (C-Terminus) IHC-plus; KIF5B; Kinesin 1 (110-120kD); KINH; KNS; Kinesin family member 5B; Kinesin heavy chain; KNS1; UKHC; Kinesin-1 heavy chain; Ubiquitous kinesin heavy chain; Human Kinesin Heavy Chain; KIF5B
other names :
kinesin-1 heavy chain; Kinesin-1 heavy chain; kinesin-1 heavy chain; kinesin heavy chain; kinesin 1 (110-120kD); ubiquitous kinesin heavy chain; conventional kinesin heavy chain; epididymis secretory protein Li 61; kinesin family member 5B; Conventional kinesin heavy chain; Ubiquitous kinesin heavy chain; UKHC
products gene name :
KIF5B
other gene names :
KIF5B; KIF5B; KNS; KINH; KNS1; UKHC; HEL-S-61; KNS; KNS1; UKHC
uniprot entry name :
KINH_HUMAN
reactivity :
Gibbon, Bovine, Dog, Gorilla, Human, Monkey, Pig, Rabbit. Predicted Reactivity: Horse (at least 90% immunogen sequence identity)
specificity :
Human KIF5B.
purity :
Immunoaffinity Purified
form :
Tris-buffered saline, pH 7.3, 0.5% BSA, 0.02% sodium azide
concentration :
0.5 mg/ml
storage stability :
Store at -20 degree C. Minimize freezing and thawing.
tested application :
Immunohistochemistry (IHC - Paraffin), Western Blot (WB), ELISA (EIA)
app notes :
ELISA (1:32000), IHC-P (2.5 ug/ml), WB (0.2 - 1 ug/ml). Usage: Immunohistochemistry: was validated for use in immunohistochemistry on a panel of 21 formalin-fixed, paraffin-embedded (FFPE) human tissues after heat induced antigen retrieval in pH 6.0 citrate buffer. After incubation with the primary anti.
other info1 :
Target Species: Human. Immunogen Description: Synthetic peptide C-QPVAVRGGGGKQV from the C-terminus of human KIF5B (NP_004512.1). Percent identity by BLAST analysis: Human, Gorilla, Gibbon, Monkey, Marmoset, Dog, Bovine, Rabbit, Pig (100%); Elephant, Panda, Horse (92%); Turkey, Platypus (85%).
other info2 :
Immunogen Type: Synthetic peptide. Immunogen: Kinesin Heavy Chain / KIF5B antibody was raised against synthetic peptide C-QPVAVRGGGGKQV from the C-terminus of human KIF5B (NP_004512.1). Percent identity by BLAST analysis: Human, Gorilla, Gibbon, Monkey, Marmoset, Dog, Bovine, Rabbit, Pig (100%); Elephant, Panda, Horse (92%); Turkey, Platypus (85%). Antigen Modification: C-Terminus
ncbi acc num :
NP_004512.1
ncbi gb acc num :
NM_004521.2
ncbi mol weight :
109,685 Da
ncbi pathways :
Adaptive Immune System Pathway (366160); Dopaminergic Synapse Pathway (469199); Dopaminergic Synapse Pathway (469185); Factors Involved In Megakaryocyte Development And Platelet Production Pathway (187196); Hemostasis Pathway (106028); Immune System Pathway (106386); Insulin Signaling Pathway (198845); Insulin Processing Pathway (105903); Kinesins Pathway (187197); MHC Class II Antigen Presentation Pathway (645290)
uniprot summary :
KIF5B: Microtubule-dependent motor required for normal distribution of mitochondria and lysosomes. Belongs to the kinesin-like protein family. Kinesin subfamily. Protein type: Motor; Microtubule-binding. Chromosomal Location of Human Ortholog: 10p11.22. Cellular Component: ciliary rootlet; microtubule; kinesin complex; neuron projection; membrane; perinuclear region of cytoplasm; endocytic vesicle; cytoplasm; microtubule organizing center; vesicle. Molecular Function: protein binding; plus-end-directed microtubule motor activity; microtubule binding; ATPase activity; microtubule motor activity; ATP binding. Biological Process: axon guidance; regulation of membrane potential; cellular protein metabolic process; positive regulation of potassium ion transport; vesicle transport along microtubule; positive regulation of synaptic transmission, GABAergic; cytoplasm organization and biogenesis; cytoskeleton-dependent intracellular transport; microtubule-based movement