This webpage contains legacy information. The product is either no longer available from the supplier or has been delisted at Labome.
product summary
company name :
MyBioSource
product type :
antibody
product name :
Goat Polyclonal to Human PC / Pyruvate Carboxylase
catalog :
MBS242056
quantity :
0.05 mg
price :
495 USD
clonality :
polyclonal
host :
goat
conjugate :
nonconjugated
reactivity :
human, mouse, rat, dog, cow
application :
western blot, ELISA, immunohistochemistry, enzyme immunoassay
product information
catalog number :
MBS242056
products type :
Antibody
products full name :
Goat Polyclonal to Human PC / Pyruvate Carboxylase
products short name :
PC / Pyruvate Carboxylase
products name syn :
Anti-PC / Pyruvate Carboxylase Antibody (Internal) IHC-plus; PC; PCB; Pyruvate carboxylase; Pyruvic carboxylase; Human PC; Pyruvate Carboxylase
other names :
pyruvate carboxylase, mitochondrial; Pyruvate carboxylase, mitochondrial; pyruvate carboxylase, mitochondrial; pyruvic carboxylase; pyruvate carboxylase; Pyruvic carboxylase; PCB
products gene name :
PC
other gene names :
PC; PC; PCB; PCB
uniprot entry name :
PYC_HUMAN
clonality :
Polyclonal
host :
Goat
reactivity :
Bat, Gibbon, Bovine, Dog, Gorilla, Hamster, Horse, Human, Monkey, Mouse, Pig, Rabbit, Rat. Predicted Reactivity: Goat (at least 90% immunogen sequence identity)
sequence length :
1178
specificity :
Human PC / Pyruvate Carboxylase. All reported variants (NP_000911.2; NP_001035806.1; NP_071504.2) represent identical protein.
purity :
Immunoaffinity Purified
form :
Tris-buffered saline, pH 7.3, 0.5% BSA, 0.02% sodium azide
concentration :
0.5 mg/ml
storage stability :
Store at -20 degree C. Minimize freezing and thawing.
tested application :
Immunohistochemistry (IHC - Paraffin), Western Blot (WB), ELISA (EIA)
app notes :
ELISA (1:16000), IHC-P (5 ug/ml), WB (0.03 - 0.1 ug/ml). Usage: Immunohistochemistry: was validated for use in immunohistochemistry on a panel of 21 formalin-fixed, paraffin-embedded (FFPE) human tissues after heat induced antigen retrieval in pH 6.0 citrate buffer. After incubation with the primary anti.
other info1 :
Target Species: Human. Immunogen Description: Synthetic peptide C-KFKEVKKAYVEANQ from an internal region of human PC / Pyruvate Carboxylase (NP_000911.2; NP_001035806.1; NP_071504.2).
other info2 :
Immunogen Type: Synthetic peptide. Immunogen: PC / Pyruvate Carboxylase antibody was raised against synthetic peptide C-KFKEVKKAYVEANQ from an internal region of human PC / Pyruvate Carboxylase (NP_000911.2; NP_001035806.1; NP_071504.2). Percent identity by BLAST analysis: Human, Gorilla, Gibbon, Monkey, Marmoset, Mouse, Rat, Hamster, Panda, Dog, Bat, Bovine, Horse, Rabbit, Pig (100%); Goat, Stickleback, Pufferfish (93%); Opossum, Chicken, Xenopus, Zebrafish (86%). Antigen Modification: Internal
ncbi gi num :
106049295
ncbi acc num :
NP_000911.2
ncbi gb acc num :
NM_000920.3
uniprot acc num :
P11498
ncbi mol weight :
57,925 Da
ncbi pathways :
Alanine And Aspartate Metabolism Pathway 198783!!Biosynthesis Of Amino Acids Pathway 790012!!Biosynthesis Of Amino Acids Pathway 795174!!Biotin Transport And Metabolism Pathway 106257!!Carbon Metabolism Pathway 814926!!Carbon Metabolism Pathway 817567!!Citrate Cycle (TCA Cycle) Pathway 82927!!Citrate Cycle (TCA Cycle) Pathway 288!!Defective AMN Causes Hereditary Megaloblastic Anemia 1 Pathway 906000!!Defective BTD Causes Biotidinase Deficiency Pathway 906015
ncbi summary :
This gene encodes pyruvate carboxylase, which requires biotin and ATP to catalyse the carboxylation of pyruvate to oxaloacetate. The active enzyme is a homotetramer arranged in a tetrahedron which is located exclusively in the mitochondrial matrix. Pyruvate carboxylase is involved in gluconeogenesis, lipogenesis, insulin secretion and synthesis of the neurotransmitter glutamate. Mutations in this gene have been associated with pyruvate carboxylase deficiency. Alternatively spliced transcript variants with different 5' UTRs, but encoding the same protein, have been found for this gene. [provided by RefSeq, Jul 2008]
size :
0.05 mg
price :
495 USD
company information
MyBioSource
P.O. Box 153308
San Diego, CA 92195-3308
sales@mybiosource.com
https://www.mybiosource.com
1-888-627-0165
headquarters: USA
MyBioSource, LLC was orginally founded in Vancouver by three enthusiastic scientists who are passionate about providing the world with the best reagents available. Together, they form a company with a big vision known as MyBioSource. MyBioSource is now located in San Diego, California, USA.

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