catalog number :
MBS242037
products full name :
Rabbit Polyclonal to Human PLTP
products short name :
PLTP
products name syn :
Anti-PLTP Antibody IHC-plus; PLTP; BPI fold containing family E; BPIFE; Phospholipid transfer protein; Lipid transfer protein II; HDLCQ9; Human PLTP
other names :
phospholipid transfer protein isoform a; Phospholipid transfer protein; phospholipid transfer protein; lipid transfer protein II; BPI fold containing family E; phospholipid transfer protein; Lipid transfer protein II
products gene name :
PLTP
other gene names :
PLTP; PLTP; BPIFE; HDLCQ9
uniprot entry name :
PLTP_HUMAN
reactivity :
Human, Mouse
specificity :
The antibody recognizes 55 kD PLTP of human and mouse origins.
purity :
Protein G Purified
form :
PBS, 1 % BSA, 0.02% Thimerosal.
storage stability :
Long term: -70 degree C; Short term: -20 degree C
tested application :
Immunohistochemistry (IHC - Paraffin), Western Blot (WB)
app notes :
IHC-P (1:100), WB (1:200 - 1:1000). Usage: Immunohistochemistry: was validated for use in immunohistochemistry on a panel of 21 formalin-fixed, paraffin-embedded (FFPE) human tissues after heat induced antigen retrieval in pH 6.0 citrate buffer. After incubation with the primary anti.
other info1 :
Target Species: Human. Immunogen Description: Synthetic peptide surrounding amino acid 473 of human PLTP.
other info2 :
Immunogen Type: Synthetic peptide. Immunogen: PLTP antibody was raised against synthetic peptide surrounding amino acid 473 of human PLTP.
ncbi acc num :
NP_006218.1
ncbi gb acc num :
NM_006227.3
ncbi mol weight :
44,847 Da
ncbi pathways :
HDL-mediated Lipid Transport Pathway (106158); Lipid Digestion, Mobilization, And Transport Pathway (106111); Lipoprotein Metabolism Pathway (106156); Metabolism Pathway (477135); Metabolism Of Lipids And Lipoproteins Pathway (160976); PPAR Signaling Pathway (83042); PPAR Signaling Pathway (450); Statin Pathway (198852)
ncbi summary :
The protein encoded by this gene is one of at least two lipid transfer proteins found in human plasma. The encoded protein transfers phospholipids from triglyceride-rich lipoproteins to high density lipoprotein (HDL). In addition to regulating the size of HDL particles, this protein may be involved in cholesterol metabolism. At least two transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Jul 2008]
uniprot summary :
PLTP: Converts HDL into larger and smaller particles. May play a key role in extracellular phospholipid transport and modulation of hdl particles. Belongs to the BPI/LBP/Plunc superfamily. BPI/LBP family. 2 isoforms of the human protein are produced by alternative splicing. Protein type: Secreted; Lipid-binding; Secreted, signal peptide. Chromosomal Location of Human Ortholog: 20q13.12. Cellular Component: extracellular space; extracellular region. Molecular Function: lipid binding. Biological Process: sperm motility; vitamin E biosynthetic process; lipid metabolic process; lipid transport