catalog number :
MBS242035
products full name :
Goat Polyclonal to Human GDF15
products short name :
GDF15
products name syn :
Anti-GDF15 Antibody (C-Terminus) IHC-plus; GDF15; MIC1; MIC-1; NAG-1; NRG-1; NSAID-regulated gene 1 protein; PLAB; NSAID-activated gene 1 protein; Placental TGF-beta; PTGFB; GDF-15; PTGF-beta; Human GDF15
other names :
growth/differentiation factor 15; Growth/differentiation factor 15; growth/differentiation factor 15; NRG-1; PTGF-beta; placental TGF-beta; NSAID-activated gene 1 protein; NSAID-regulated gene 1 protein; prostate differentiation factor; macrophage inhibitory cytokine 1; placental bone morphogenetic protein; NSAID (nonsteroidal anti-inflammatory drug)-activated protein 1; growth differentiation factor 15; Macrophage inhibitory cytokine 1; MIC-1; NSAID-activated gene 1 protein; NAG-1; NSAID-regulated gene 1 protein; NRG-1; Placental TGF-beta; Placental bone morphogenetic protein; Prostate differentiation factor
products gene name :
GDF15
other gene names :
GDF15; GDF15; PDF; MIC1; PLAB; MIC-1; NAG-1; PTGFB; GDF-15; MIC1; PDF; PLAB; PTGFB; GDF-15; MIC-1; NAG-1; NRG-1
uniprot entry name :
GDF15_HUMAN
reactivity :
Gibbon, Gorilla, Human. Predicted Reactivity: Monkey (at least 90% immunogen sequence identity)
specificity :
Human GDF15.
purity :
Immunoaffinity Purified
form :
Tris-buffered saline, pH 7.3, 0.5% BSA, 0.02% sodium azide
concentration :
0.5 mg/ml
storage stability :
Store at -20 degree C. Minimize freezing and thawing.
tested application :
Immunohistochemistry (IHC - Paraffin), Western Blot (WB), ELISA (EIA)
app notes :
ELISA (1:2000), IHC-P (5 ug/ml), WB (0.1 - 0.3 ug/ml). Usage: Immunohistochemistry: was validated for use in immunohistochemistry on a panel of 21 formalin-fixed, paraffin-embedded (FFPE) human tissues after heat induced antigen retrieval in pH 6.0 citrate buffer. After incubation with the primary anti.
other info1 :
Target Species: Human. Immunogen Description: Synthetic peptide C-QKTDTGVSLQTYDD from the C-terminus of human GDF15 (NP_004855.2). Percent identity by BLAST analysis: Human, Gorilla, Gibbon, Monkey (100%); Marmoset (93%).
other info2 :
Immunogen Type: Synthetic peptide. Immunogen: GDF15 antibody was raised against synthetic peptide C-QKTDTGVSLQTYDD from the C-terminus of human GDF15 (NP_004855.2). Percent identity by BLAST analysis: Human, Gorilla, Gibbon, Monkey (100%); Marmoset (93%). Antigen Modification: C-Terminus
products categories :
Family: TGF beta
products description :
Growth differentiation factor 15 (GDF15) is a protein belonging to the transforming growth factor beta superfamily that has a role in regulating inflammatory and apoptotic pathways in injured tissues and during disease processes. GDF15 is also known as TGF-PL, MIC-1, PDF, PLAB, and PTGFB. GDF15 mRNA is most abundant in the liver, with lower levels seen in some other tissues.
ncbi acc num :
NP_004855.2
ncbi gb acc num :
NM_004864.2
ncbi mol weight :
34,140 Da
ncbi pathways :
Direct P53 Effectors Pathway 137939
ncbi summary :
Bone morphogenetic proteins (e.g., BMP9; MIM 605120) are members of the transforming growth factor-beta (see TGFB1; MIM 190180) superfamily and regulate tissue differentiation and maintenance. They are synthesized as precursor molecules that are processed at a dibasic cleavage site to release C-terminal domains containing a characteristic motif of 7 conserved cysteines in the mature protein.[supplied by OMIM, Oct 2009]