catalog number :
MBS242003
products full name :
Goat Polyclonal to Human GSTP1 / GST Pi
products short name :
GSTP1 / GST Pi
products name syn :
Anti-GSTP1 / GST Pi Antibody (Internal) IHC-plus; GSTP1; Deafness; X-linked 7; DFN7; GSTP1-1; Glutathione S-transferase P; GST Pi; GSTP; FAEES3; Glutathione S-transferase pi 1; GST class-pi; GST3; PI; Human GSTP1; GST Pi
other names :
glutathione S-transferase P; Glutathione S-transferase P; glutathione S-transferase P; GSTP1-1; GST class-pi; deafness, X-linked 7; epididymis secretory protein Li 22; fatty acid ethyl ester synthase III; glutathione S-transferase pi 1; GST class-pi; GSTP1-1
products gene name :
GSTP1
products gene name syn :
GST Pi
other gene names :
GSTP1; GSTP1; PI; DFN7; GST3; GSTP; FAEES3; HEL-S-22; FAEES3; GST3
uniprot entry name :
GSTP1_HUMAN
reactivity :
Bat, Gibbon, Bovine, Dog, Gorilla, Hamster, Horse, Human, Monkey, Mouse, Orangutan, Pig, Rat. Predicted Reactivity: Goat (at least 90% immunogen sequence identity)
specificity :
Human GSTP1.
purity :
Immunoaffinity Purified
form :
Tris-buffered saline, pH 7.3, 0.5% BSA, 0.02% sodium azide
concentration :
0.5 mg/ml
storage stability :
Store at -20 degree C. Minimize freezing and thawing.
tested application :
Immunohistochemistry (IHC - Paraffin), Western Blot (WB), ELISA (EIA)
app notes :
ELISA (1:32000), IHC-P (5 ug/ml), WB (0.01 - 0.03 ug/ml). Usage: Immunohistochemistry: was validated for use in immunohistochemistry on a panel of 21 formalin-fixed, paraffin-embedded (FFPE) human tissues after heat induced antigen retrieval in pH 6.0 citrate buffer. After incubation with the primary anti.
other info1 :
Target Species: Human. Immunogen Description: Synthetic peptide C-LADQGQSWKEEV from an internal region of human GSTP1 (NP_000843.1). Percent identity by BLAST analysis: Human, Gorilla, Orangutan, Gibbon, Monkey, Marmoset, Mouse, Rat, Hamster, Panda, Dog, Bat, Bovine, Horse, Pig (100%).
other info2 :
Immunogen Type: Synthetic peptide. Immunogen: GSTP1 / GST Pi antibody was raised against synthetic peptide C-LADQGQSWKEEV from an internal region of human GSTP1 (NP_000843.1). Percent identity by BLAST analysis: Human, Gorilla, Orangutan, Gibbon, Monkey, Marmoset, Mouse, Rat, Hamster, Panda, Dog, Bat, Bovine, Horse, Pig (100%); Goat, Elephant (92%); Pike (83%). Antigen Modification: Internal
ncbi acc num :
NP_000843.1
ncbi gb acc num :
NM_000852.3
ncbi mol weight :
23,356 Da
ncbi pathways :
4-hydroxy-2-nonenal Detoxification Pathway 703096!!Arachidonate Epoxygenase / Epoxide Hydrolase Pathway 198838!!Biological Oxidations Pathway 105698!!Cellular Responses To Stress Pathway 645258!!Chemical Carcinogenesis Pathway 673221!!Chemical Carcinogenesis Pathway 673237!!Defective AHCY Causes Hypermethioninemia With S-adenosylhomocysteine Hydrolase Deficiency (HMAHCHD) Pathway 1127639!!Defective GCLC Causes Hemolytic Anemia Due To Gamma-glutamylcysteine Synthetase Deficiency (HAGGSD) Pathway 1127658!!Defective GGT1 Causes Glutathionuria (GLUTH) Pathway 1127659!!Defective GSS Causes Glutathione Synthetase Deficiency (GSS Deficiency) Pathway 1127660
ncbi summary :
Glutathione S-transferases (GSTs) are a family of enzymes that play an important role in detoxification by catalyzing the conjugation of many hydrophobic and electrophilic compounds with reduced glutathione. Based on their biochemical, immunologic, and structural properties, the soluble GSTs are categorized into 4 main classes: alpha, mu, pi, and theta. This GST family member is a polymorphic gene encoding active, functionally different GSTP1 variant proteins that are thought to function in xenobiotic metabolism and play a role in susceptibility to cancer, and other diseases. [provided by RefSeq, Jul 2008]