This webpage contains legacy information. The product is either no longer available from the supplier or has been delisted at Labome.
product summary
company name :
MyBioSource
product type :
antibody
product name :
Rabbit Polyclonal to Human SMAD3
catalog :
MBS241861
quantity :
0.05 mg
price :
495 USD
clonality :
polyclonal
host :
rabbit
conjugate :
nonconjugated
reactivity :
human, mouse, rat, dog, cow
application :
western blot, immunohistochemistry
product information
catalog number :
MBS241861
products type :
Antibody
products full name :
Rabbit Polyclonal to Human SMAD3
products short name :
SMAD3
products name syn :
Anti-SMAD3 Antibody (aa100-150) IHC-plus; SMAD3; HSPC193; HMAD-3; HsT17436; LDS1C; LDS3; Mad homolog JV15-2; MAD3; MADH3; Mothers against DPP homolog 3; JV15-2; SMA- and MAD-related protein 3; SMAD family member 3; MAD homolog 3; HSMAD3; Mad protein homolog; SMAD 3; Human SMAD3
other names :
mothers against decapentaplegic homolog 3 isoform 1; Mothers against decapentaplegic homolog 3; mothers against decapentaplegic homolog 3; mad3; hMAD-3; hSMAD3; MAD homolog 3; mad homolog JV15-2; mad protein homolog; mothers against DPP homolog 3; SMA- and MAD-related protein 3; SMAD, mothers against DPP homolog 3; MAD, mothers against decapentaplegic homolog 3; SMAD family member 3; JV15-2; SMAD family member 3; SMAD 3; Smad3; hSMAD3
products gene name :
SMAD3
other gene names :
SMAD3; SMAD3; LDS3; LDS1C; MADH3; JV15-2; HSPC193; HsT17436; MADH3; MAD homolog 3; Mad3; Mothers against DPP homolog 3; hMAD-3; SMAD 3; Smad3; hSMAD3
uniprot entry name :
SMAD3_HUMAN
clonality :
Polyclonal
host :
Rabbit
reactivity :
Bovine, Dog, Human, Macaque, Monkey, Mouse, Pig, Rat
sequence length :
425
specificity :
A portion of amino acids 100-150 of human SMAD3 was used as the immunogen.
purity :
Protein G Purified
form :
PBS, 0.2% gelatin, 0.05% sodium azide.
concentration :
0.5 mg/ml
storage stability :
Short term 4 degree C, long term aliquot and store at -20 degree C, avoid freeze thaw cycles.
tested application :
Immunohistochemistry (IHC - Paraffin), Western Blot (WB)
app notes :
IHC-P (10 ug/ml), WB (0.5 - 2 ug/ml). Usage: Immunohistochemistry: was validated for use in immunohistochemistry on a panel of 21 formalin-fixed, paraffin-embedded (FFPE) human tissues after heat induced antigen retrieval in pH 6.0 citrate buffer. After incubation with the primary anti.
other info1 :
Target Species: Human
other info2 :
Antigen Modification: aa100-150
products description :
SMAD3, a transcriptional regulator, is activated by TGF-beta and Activin 1 receptor kinase. SMAD3 recognizes an 8 bp palindromic sequence GTCTAGAC. Upon phosphorylation at two extreme C-terminal serines, SMAD3 is translocated into the nucleus where is forms complexes other SMAD proteins, depending on the activation pathway, and regulates the transcription of target genes.
ncbi gi num :
5174513
ncbi acc num :
NP_005893.1
ncbi gb acc num :
NM_005902.3
uniprot acc num :
P84022
ncbi mol weight :
25,722 Da
ncbi pathways :
AGE/RAGE Pathway 698754!!Activin Signaling Pathway 1084757!!Activin Signaling Pathway 1108220!!Adherens Junction Pathway 83070!!Adherens Junction Pathway 481!!Adipogenesis Pathway 198832!!Alpha6-Beta4 Integrin Signaling Pathway 198807!!Androgen Receptor Signaling Pathway 198806!!Cell Cycle Pathway 198811!!Cell Cycle Pathway 83054
ncbi summary :
The protein encoded by this gene belongs to the SMAD, a family of proteins similar to the gene products of the Drosophila gene 'mothers against decapentaplegic' (Mad) and the C. elegans gene Sma. SMAD proteins are signal transducers and transcriptional modulators that mediate multiple signaling pathways. This protein functions as a transcriptional modulator activated by transforming growth factor-beta and is thought to play a role in the regulation of carcinogenesis. [provided by RefSeq, Apr 2009]
size :
0.05 mg
price :
495 USD
company information
MyBioSource
P.O. Box 153308
San Diego, CA 92195-3308
sales@mybiosource.com
https://www.mybiosource.com
1-888-627-0165
headquarters: USA
MyBioSource, LLC was orginally founded in Vancouver by three enthusiastic scientists who are passionate about providing the world with the best reagents available. Together, they form a company with a big vision known as MyBioSource. MyBioSource is now located in San Diego, California, USA.

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