Rabbit Polyclonal to Human OLFM4 / Olfactomedin 4 | MyBioSource MBS241855 product information

product summary

company name :

MyBioSource

product type :

antibody

product name :

Rabbit Polyclonal to Human OLFM4 / Olfactomedin 4

catalog :

MBS241855

quantity :

0.05 mg

price :

495 USD

clonality :

polyclonal

host :

rabbit

conjugate :

nonconjugated

reactivity :

human

application :

western blot, immunohistochemistry

more info or order :

MyBioSource product webpage

product information

catalog number :

MBS241855

products type :

Antibody

products full name :

Rabbit Polyclonal to Human OLFM4 / Olfactomedin 4

products short name :

OLFM4 / Olfactomedin 4

products name syn :

Anti-OLFM4 / Olfactomedin 4 Antibody (aa400-450) IHC-plus; OLFM4; Antiapoptotic protein GW112; HOLfD; HGC-1; GW112; OlfD; OLM4; UNQ362; Olfactomedin 4; Olfactomedin-4; BA209J19.1; GC1; HCG-1; Human OLFM4; Olfactomedin 4

other names :

olfactomedin-4; Olfactomedin-4; olfactomedin-4; antiapoptotic protein GW112; G-CSF-stimulated clone 1 protein; olfactomedin 4; Antiapoptotic protein GW112; G-CSF-stimulated clone 1 protein; hGC-1; hOLfD

products gene name :

OLFM4

other gene names :

OLFM4; OLFM4; GC1; OLM4; OlfD; GW112; hGC-1; hOLfD; UNQ362; bA209J19.1; GW112; OLM4; hGC-1

uniprot entry name :

OLFM4_HUMAN

clonality :

Polyclonal

host :

Rabbit

reactivity :

Gibbon, Human. Predicted Reactivity: Gorilla, Monkey (at least 90% immunogen sequence identity)

sequence length :

510

specificity :

A portion of amino acids 400-450 of human Olfactomedin 4

purity :

Immunoaffinity Purified

form :

PBS, 0.05% BSA, 0.05% sodium azide.

concentration :

0.5 mg/ml

storage stability :

Long term: -20 degree C; Short term: +4 degree C. Avoid repeat freeze-thaw cycles.

tested application :

Immunohistochemistry (IHC - Paraffin), Western Blot (WB)

app notes :

IHC-P (5 ug/ml), WB (0.5 - 2 ug/ml). Usage: Immunohistochemistry: was validated for use in immunohistochemistry on a panel of 21 formalin-fixed, paraffin-embedded (FFPE) human tissues after heat induced antigen retrieval in pH 6.0 citrate buffer. After incubation with the primary anti.

other info1 :

Target Species: Human. Immunogen Description: A synthetic peptide corresponding to amino acids 400-419 (YVYNDGYLLNYDLSVLQKPQ) of human OLFM4 was used as immunogen for this antibody. Percent identity by BLAST analysis: Human, Gibbon (100%); Gorilla, Marmoset (95%); Monkey, Mouse, Rat (85%).

other info2 :

Immunogen Type: Synthetic peptide. Immunogen: OLFM4 / Olfactomedin 4 antibody was raised against a synthetic peptide corresponding to amino acids 400-419 (YVYNDGYLLNYDLSVLQKPQ) of human OLFM4 was used as immunogen for this antibody. Percent identity by BLAST analysis: Human, Gibbon (100%); Gorilla, Marmoset (95%); Monkey, Mouse, Rat (85%). Antigen Modification: aa400-450

products categories :

Family: Olfactomedin

products description :

Olfactomedin 4 (OLFM4) was originally cloned from human myeloblasts and found to be selectively expressed in inflammed colonic epithelium. This gene encodes a member of the olfactomedin family. The encoded protein is an antiapoptotic factor that promotes tumor growth and is an extracellular matrix glycoprotein that facilitates cell adhesion.

ncbi gi num :

32313593

ncbi acc num :

NP_006409.3

ncbi gb acc num :

NM_006418.4

uniprot acc num :

Q6UX06

ncbi mol weight :

57,280 Da

ncbi summary :

This gene was originally cloned from human myeloblasts and found to be selectively expressed in inflammed colonic epithelium. This gene encodes a member of the olfactomedin family. The encoded protein is an antiapoptotic factor that promotes tumor growth and is an extracellular matrix glycoprotein that facilitates cell adhesion. [provided by RefSeq, Mar 2011]

uniprot summary :

OLFM4: May promote proliferation of pancreatic cancer cells by favoring the transition from the S to G2/M phase. In myeloid leukemic cell lines, inhibits cell growth and induces cell differentiation and apoptosis. May play a role in the inhibition of EIF4EBP1 phosphorylation/deactivation. Facilitates cell adhesion, most probably through interaction with cell surface lectins and cadherin. Protein type: Secreted, signal peptide; Secreted. Chromosomal Location of Human Ortholog: 13q14.3. Cellular Component: extracellular space; azurophil granule; specific granule; mitochondrion; perinuclear region of cytoplasm; plasma membrane; secretory granule. Molecular Function: protein homodimerization activity; cadherin binding; catalytic activity. Biological Process: regulation of apoptosis; metabolic process; negative regulation of immune response; negative regulation of I-kappaB kinase/NF-kappaB cascade; regulation of phagocytosis; cell adhesion; protein homooligomerization

size1 :

0.05 mg

price1 :

495 USD

more info or order :

MyBioSource product webpage