Rabbit Polyclonal (IgG) to Human ACKR3 / CXCR7 | MyBioSource MBS241706 product information

This webpage contains legacy information. The product is either no longer available from the supplier or has been delisted at Labome.

product summary

company name :

MyBioSource

product type :

antibody

product name :

Rabbit Polyclonal (IgG) to Human ACKR3 / CXCR7

catalog :

MBS241706

quantity :

0.05 mg

price :

495 USD

clonality :

polyclonal

host :

rabbit

conjugate :

nonconjugated

reactivity :

human, mouse, rat, dog, cow

application :

western blot, immunohistochemistry, flow cytometry, FACS

product information

catalog number :

MBS241706

products type :

Antibody

products full name :

Rabbit Polyclonal (IgG) to Human ACKR3 / CXCR7

products short name :

ACKR3 / CXCR7 / RDC1

products name syn :

Anti-ACKR3 / CXCR7 / RDC1 Antibody (aa100-150) IHC-plus; ACKR3; Chemokine orphan receptor 1; CMKOR1; CXCR7; CXC-R7; GPRN1; RDC1; RDC-1; CXCR-7; G-protein coupled receptor 159; GPR159; Human ACKR3; CXCR7

other names :

atypical chemokine receptor 3; Atypical chemokine receptor 3; atypical chemokine receptor 3; G protein-coupled receptor; chemokine orphan receptor 1; G-protein coupled receptor 159; C-X-C chemokine receptor type 7; chemokine (C-X-C motif) receptor 7; G-protein coupled receptor RDC1 homolog; atypical chemokine receptor 3; C-X-C chemokine receptor type 7; CXC-R7; CXCR-7; Chemokine orphan receptor 1; G-protein coupled receptor 159; G-protein coupled receptor RDC1 homolog; RDC-1

products gene name :

ACKR3

products gene name syn :

CXCR7; RDC1

other gene names :

ACKR3; ACKR3; RDC1; CXCR7; RDC-1; CMKOR1; CXC-R7; CXCR-7; GPR159; CMKOR1; CXCR7; GPR159; RDC1; CXC-R7; CXCR-7; RDC-1

uniprot entry name :

ACKR3_HUMAN

clonality :

Polyclonal

isotype :

IgG

host :

Rabbit

reactivity :

Bat, Gibbon, Bovine, Dog, Gorilla, Hamster, Horse, Human, Monkey, Mouse, Pig, Rabbit, Rat. Predicted Reactivity: Xenopus (at least 90% immunogen sequence identity)

sequence length :

362

specificity :

A portion of amino acids 100-150 of human RDC1

purity :

Protein G Purified

form :

PBS, 0.05% BSA, 0.05% sodium azide.

concentration :

0.5 mg/ml

storage stability :

Short term 4 degree C, long term aliquot and store at -20 degree C, avoid freeze thaw cycles.

tested application :

Immunohistochemistry (IHC - Paraffin), Western Blot (WB), Flow Cytometry (FC/FACS)

app notes :

Flo (1 - 10 ug/ml), IHC-P (10 ug/ml), WB (4 - 6 ug/ml). Usage: Immunohistochemistry: was validated for use in immunohistochemistry on a panel of 21 formalin-fixed, paraffin-embedded (FFPE) human tissues after heat induced antigen retrieval in pH 6.0 citrate buffer. After incubation with the primary anti.

other info1 :

Target Species: Human. Immunogen Description: A synthetic peptide (QHNQWPMGELTC) corresponding amino acids 106-117 of human CXCR7/RDC1 was used as the immunogen, GenBank NP_064707.1.

other info2 :

Immunogen Type: Synthetic peptide. Immunogen: ACKR3 / CXCR7 antibody was raised against a synthetic peptide (QHNQWPMGELTC) corresponding amino acids 106-117 of human CXCR7/RDC1 was used as the immunogen, GenBank NP_064707.1. Percent identity by BLAST analysis: Human, Gorilla, Gibbon, Monkey, Marmoset, Mouse, Rat, Hamster, Elephant, Panda, Bovine, Bat, Dog, Horse, Rabbit, Pig, Opossum (100%); Platypus, Xenopus (92%); Turkey (83%). Antigen Modification: aa100-150

products categories :

Family: GPCR. Subfamily: Chemokine

products description :

RDC1 was originally considered to be an Adrenomedullin receptor that binds calcitonin gene-related peptide (CGRP) and adrenomedullin. RDC1 and GPRN1 represent two tissue-specific subtypes of the same 60-kD receptor. RDC1 has the structural characteristics of a chemokine receptor. Recently it has been shown that RDC1 binds to the chemokine CXCL12 and should be considered to be a chemokine receptor.

ncbi gi num :

31083344

ncbi acc num :

NP_064707.1

ncbi gb acc num :

NM_020311.2

uniprot acc num :

P25106

ncbi mol weight :

41,493 Da

ncbi pathways :

Chemokine Receptors Bind Chemokines Pathway 106359!!Class A/1 (Rhodopsin-like Receptors) Pathway 106357!!Cytokine-cytokine Receptor Interaction Pathway 83051!!Cytokine-cytokine Receptor Interaction Pathway 460!!Defective ACTH Causes Obesity And Pro-opiomelanocortinin Deficiency (POMCD) Pathway 1127664!!Disease Pathway 530764!!G Alpha (i) Signalling Events Pathway 119550!!GPCR Downstream Signaling Pathway 119548!!GPCR Ligand Binding Pathway 161020!!GPCRs, Class A Rhodopsin-like Pathway 198886

ncbi summary :

This gene encodes a member of the G-protein coupled receptor family. Although this protein was earlier thought to be a receptor for vasoactive intestinal peptide (VIP), it is now considered to be an orphan receptor, in that its endogenous ligand has not been identified. The protein is also a coreceptor for human immunodeficiency viruses (HIV). Translocations involving this gene and HMGA2 on chromosome 12 have been observed in lipomas. [provided by RefSeq, Jul 2008]

size :

0.05 mg

price :

495 USD