catalog number :
MBS241705
products full name :
Rabbit Polyclonal to Human FOXO3 / FOXO3A
products short name :
FOXO3 / FOXO3A
products name syn :
Anti-FOXO3 / FOXO3A Antibody (aa600-673) IHC-plus; FOXO3; AF6q21; AF6q21 protein; Forkhead box O3; Forkhead box O3A; FOXO3A; FKHRL1P2; Forkhead box protein O3; FOXO2; FKHRL1; Human FOXO3; FOXO3A
other names :
forkhead box protein O3; Forkhead box protein O3; forkhead box protein O3; forkhead box O3A; forkhead in rhabdomyosarcoma-like 1; forkhead homolog (rhabdomyosarcoma) like 1; forkhead, Drosophila, homolog of, in rhabdomyosarcoma-like 1; forkhead box O3; AF6q21 protein; Forkhead in rhabdomyosarcoma-like 1
products gene name :
FOXO3
products gene name syn :
FOXO3A
other gene names :
FOXO3; FOXO3; FOXO2; AF6q21; FKHRL1; FOXO3A; FKHRL1P2; FKHRL1; FOXO3A
uniprot entry name :
FOXO3_HUMAN
reactivity :
Bovine, Chicken, Dog, Xenopus, Human, Monkey, Mouse, Rat
specificity :
A portion of amino acids 600-673 of human FOXO3A
purity :
Immunoaffinity Purified
form :
PBS, 0.05% BSA, 0.05% sodium azide.
concentration :
0.5 mg/ml
storage stability :
Short term 4 degree C, long term aliquot and store at -20 degree C, avoid freeze thaw cycles.
tested application :
Immunohistochemistry (IHC - Paraffin), Western Blot (WB)
app notes :
IHC-P (10 ug/ml), WB (2 - 4 ug/ml). Usage: Immunohistochemistry: was validated for use in immunohistochemistry on a panel of 21 formalin-fixed, paraffin-embedded (FFPE) human tissues after heat induced antigen retrieval in pH 6.0 citrate buffer. After incubation with the primary anti.
other info1 :
Target Species: Human. Immunogen Description: Synthetic peptide from human FOXO3 / FOXO3A.
other info2 :
Immunogen Type: Synthetic peptide. Immunogen: FOXO3 / FOXO3A antibody was raised against synthetic peptide from human FOXO3 / FOXO3A. Antigen Modification: aa600-673
products categories :
Family: Transcription factor
ncbi acc num :
NP_001446.1
ncbi gb acc num :
NM_001455.3
ncbi mol weight :
48,406 Da
ncbi pathways :
AKT Phosphorylates Targets In The Nucleus Pathway 106476!!AMPK Signaling Pathway 989139!!AMPK Signaling Pathway 992181!!Adaptive Immune System Pathway 366160!!BDNF Signaling Pathway 712093!!Chemokine Signaling Pathway 99051!!Chemokine Signaling Pathway 96864!!Class I PI3K Signaling Events Pathway 138022!!Class I PI3K Signaling Events Mediated By Akt Pathway 138020!!Constitutive PI3K/AKT Signaling In Cancer Pathway 685535
ncbi summary :
This gene belongs to the forkhead family of transcription factors which are characterized by a distinct forkhead domain. This gene likely functions as a trigger for apoptosis through expression of genes necessary for cell death. Translocation of this gene with the MLL gene is associated with secondary acute leukemia. Alternatively spliced transcript variants encoding the same protein have been observed. [provided by RefSeq, Jul 2008]