catalog number :
MBS241699
products full name :
Rabbit Polyclonal (IgG) to Human HSP90B1 / GP96 / GRP94
products short name :
HSP90B1 / GP96 / GRP94
products name syn :
Anti-HSP90B1 / GP96 / GRP94 Antibody (aa590-640) IHC-plus; ECGP; Endoplasmin; gp96 homolog; gp96; GRP-94; GRP94; Tumor rejection antigen 1; TRA1; Human HSP90B1; GP96; GRP94
other names :
endoplasmin; Endoplasmin; endoplasmin; tumor rejection antigen 1; epididymis luminal protein 35; 94 kDa glucose-regulated protein; tumor rejection antigen (gp96) 1; endothelial cell (HBMEC) glycoprotein; heat shock protein 90 kDa beta member 1; stress-inducible tumor rejection antigen gp96; epididymis secretory sperm binding protein Li 125m; heat shock protein 90kDa beta (Grp94), member 1; 94 kDa glucose-regulated protein; GRP-94; Heat shock protein 90 kDa beta member 1; Tumor rejection antigen 1; gp96 homolog
products gene name :
HSP90B1
products gene name syn :
GP96; GRP94
other gene names :
HSP90B1; HSP90B1; ECGP; GP96; TRA1; GRP94; HEL35; HEL-S-125m; GRP94; TRA1; GRP-94
uniprot entry name :
ENPL_HUMAN
reactivity :
Bovine, Chimpanzee, Chicken, Xenopus, Horse, Human, Monkey, Mouse, Rat, Zebrafish
specificity :
A portion of amino acids 590-640 of human GRP94
purity :
Protein G Purified
form :
PBS, 0.2% gelatin, 0.05% sodium azide.
concentration :
0.5 mg/ml
storage stability :
Short term 4 degree C, long term aliquot and store at -20 degree C, avoid freeze thaw cycles.
tested application :
Immunohistochemistry (IHC - Paraffin), Western Blot (WB)
app notes :
IHC-P (10 ug/ml), WB (0.5 - 2 ug/ml). Usage: Immunohistochemistry: was validated for use in immunohistochemistry on a panel of 21 formalin-fixed, paraffin-embedded (FFPE) human tissues after heat induced antigen retrieval in pH 6.0 citrate buffer. After incubation with the primary anti.
other info1 :
Target Species: Human. Immunogen Description: Synthetic peptide from human HSP90B1 / GRP94.
other info2 :
Immunogen Type: Synthetic peptide. Immunogen: HSP90B1 / GP96 / GRP94 antibody was raised against synthetic peptide from human HSP90B1 / GRP94. Antigen Modification: aa590-640
ncbi acc num :
NP_003290.1
ncbi gb acc num :
NM_003299.2
ncbi mol weight :
92,469 Da
ncbi pathways :
ATF6-alpha Activates Chaperone Genes Pathway 530770!!ATF6-alpha Activates Chaperones Pathway 105905!!Binding And Uptake Of Ligands By Scavenger Receptors Pathway 771599!!Estrogen Signaling Pathway 799177!!Estrogen Signaling Pathway 799197!!IL6-mediated Signaling Events Pathway 137932!!Immune System Pathway 106386!!Innate Immune System Pathway 106387!!Metabolism Of Proteins Pathway 106230!!NOD-like Receptor Signaling Pathway 122191
ncbi summary :
This gene encodes a member of a family of adenosine triphosphate(ATP)-metabolizing molecular chaperones with roles in stabilizing and folding other proteins. The encoded protein is localized to melanosomes and the endoplasmic reticulum. Expression of this protein is associated with a variety of pathogenic states, including tumor formation. There is a microRNA gene located within the 5' exon of this gene. There are pseudogenes for this gene on chromosomes 1 and 15. [provided by RefSeq, Aug 2012]