catalog number :
MBS241655
products full name :
Goat Polyclonal to Human SORBS1 / Ponsin
products short name :
SORBS1 / Ponsin
products name syn :
Anti-SORBS1 / Ponsin Antibody (C-Terminus) IHC-plus; SORBS1; C-Cbl associated protein; C-Cbl-associated protein; CAP; FLAF2; KIAA0894; KIAA1296; R85FL; SH3 domain protein 5; SH3-domain protein 5 (ponsin); SH3P12; SORB1; Fas-ligand associated factor 2; Ponsin; SH3D5; Human SORBS1; Ponsin
other names :
sorbin and SH3 domain-containing protein 1 isoform 2; Sorbin and SH3 domain-containing protein 1; sorbin and SH3 domain-containing protein 1; SORBS1; ponsin; SH3 domain protein 5; c-Cbl associated protein; Fas-ligand associated factor 2; sorbin and SH3 domain containing 1; Ponsin; SH3 domain protein 5; SH3P12; c-Cbl-associated protein; CAP
products gene name :
SORBS1
other gene names :
SORBS1; SORBS1; CAP; FLAF2; R85FL; SH3D5; SORB1; SH3P12; CAP
uniprot entry name :
SRBS1_HUMAN
reactivity :
Bat, Gibbon, Dog, Gorilla, Hamster, Horse, Human, Monkey, Mouse, Orangutan, Rat. Predicted Reactivity: Pig, Chicken (at least 90% immunogen sequence identity)
specificity :
Human SORBS1. This antibody is expected to recognize all seven reported isoforms (NP_006425.2, NP_056200.1, NP_001030126.1, NP_001030127.1, NP_001030128.1, NP_079267.1 and NP_001030129.1).
purity :
Immunoaffinity Purified
form :
Tris-buffered saline, pH 7.3, 0.5% BSA, 0.02% sodium azide
concentration :
0.5 mg/ml
storage stability :
Store at -20 degree C. Minimize freezing and thawing.
tested application :
Immunohistochemistry (IHC - Paraffin), ELISA (EIA)
app notes :
ELISA (1:16000), IHC-P (2.5 ug/ml). Usage: Immunohistochemistry: was validated for use in immunohistochemistry on a panel of 21 formalin-fixed, paraffin-embedded (FFPE) human tissues after heat induced antigen retrieval in pH 6.0 citrate buffer. After incubation with the primary anti.
other info1 :
Target Species: Human. Immunogen Description: Synthetic peptide C-GTFPGNYVKPLYL from the C-terminus of human SORBS1 (NP_006425.2; NP_056200.1; NP_001030126.1; NP_001030127.1; NP_001030128.1; NP_079267.1; NP_001030129.1).
other info2 :
Immunogen Type: Synthetic peptide. Immunogen: SORBS1 / Ponsin antibody was raised against synthetic peptide C-GTFPGNYVKPLYL from the C-terminus of human SORBS1 (NP_006425.2; NP_056200.1; NP_001030126.1; NP_001030127.1; NP_001030128.1; NP_079267.1; NP_001030129.1). Percent identity by BLAST analysis: Human, Gorilla, Orangutan, Gibbon, Monkey, Marmoset, Mouse, Rat, Dog, Bat, Hamster, Elephant, Panda, Horse, Opossum, Platypus (100%); Pig, Turkey, Chicken (92%); Zebrafish (85%). Antigen Modification: C-Terminus
ncbi acc num :
NP_056200.1
ncbi gb acc num :
NM_015385.3
ncbi mol weight :
143,741 Da
ncbi pathways :
Adherens Junction Pathway 83070!!Adherens Junction Pathway 481!!Insulin Pathway 138026!!Insulin Signaling Pathway 198845!!Insulin Signaling Pathway 83090!!Insulin Signaling Pathway 501!!Integrin-mediated Cell Adhesion Pathway 198816!!Muscle Contraction Pathway 106261!!PPAR Signaling Pathway 83042!!PPAR Signaling Pathway 450
ncbi summary :
This gene encodes a CBL-associated protein which functions in the signaling and stimulation of insulin. Mutations in this gene may be associated with human disorders of insulin resistance. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Mar 2014]