catalog number : 
MBS241643
products full name : 
Goat Polyclonal to Human MURF1 / IRF
products short name : 
MURF1 / IRF
products name syn : 
Anti-MURF1 / IRF Antibody (Internal) IHC-plus; TRIM63; Iris RING finger protein; MURF-1; MURF1; MuRF2; IRF; RING finger protein 28; RNF28; Tripartite motif-containing 63; Tripartite motif containing 63; SMRZ; Human MURF1; IRF
other names : 
E3 ubiquitin-protein ligase TRIM63; E3 ubiquitin-protein ligase TRIM63; E3 ubiquitin-protein ligase TRIM63; ring finger protein 28; iris ring finger protein; muscle specific ring finger protein 2; muscle-specific RING finger protein 1; tripartite motif-containing protein 63; striated muscle RING zinc finger protein; tripartite motif containing 63, E3 ubiquitin protein ligase; Iris RING finger protein; Muscle-specific RING finger protein 1; MuRF-1; MuRF1; RING finger protein 28; Striated muscle RING zinc finger protein; Tripartite motif-containing protein 63
products gene name : 
MURF1
products gene name syn : 
IRF; TRIM63
other gene names : 
TRIM63; TRIM63; IRF; SMRZ; MURF1; MURF2; RNF28; IRF; MURF1; RNF28; SMRZ; MuRF-1; MuRF1
uniprot entry name : 
TRI63_HUMAN
reactivity : 
Gibbon, Gorilla, Human, Monkey.  Predicted Reactivity:  Bat, Bovine, Dog, Horse (at least 90% immunogen sequence identity)
specificity : 
Human TRIM63 / MURF1.
purity : 
Immunoaffinity Purified
form : 
Tris-buffered saline, pH 7.3, 0.5% BSA, 0.02% sodium azide
concentration : 
0.5 mg/ml
storage stability : 
Store at -20 degree C. Minimize freezing and thawing.
tested application : 
Immunohistochemistry (IHC - Paraffin), ELISA (EIA)
app notes : 
ELISA (1:32000), IHC-P (1.25 ug/ml). Usage: Immunohistochemistry: was validated for use in immunohistochemistry on a panel of 21 formalin-fixed, paraffin-embedded (FFPE) human tissues after heat induced antigen retrieval in pH 6.0 citrate buffer. After incubation with the primary anti.
other info1 : 
Target Species: Human.  Immunogen Description: Synthetic peptide C-QQYQEQLDKSTKLVE from an internal region of human TRIM63 / MURF1 (NP_115977.2). Percent identity by BLAST analysis: Human, Gorilla, Gibbon, Monkey, Marmoset (100%); Dog, Bat, Bovine, Elephant, Panda, Horse (93%).
other info2 : 
Immunogen Type: Synthetic peptide.  Immunogen: MURF1 / IRF antibody was raised against synthetic peptide C-QQYQEQLDKSTKLVE from an internal region of human TRIM63 / MURF1 (NP_115977.2). Percent identity by BLAST analysis: Human, Gorilla, Gibbon, Monkey, Marmoset (100%); Dog, Bat, Bovine, Elephant, Panda, Horse (93%); Rabbit, Platypus (87%); Mouse, Rat, Hamster, Opossum (80%).  Antigen Modification: Internal
products categories : 
Family: Tripartite Motif
ncbi acc num : 
NP_115977.2
ncbi gb acc num : 
NM_032588.3
ncbi mol weight : 
36,950 Da
ncbi pathways : 
Adaptive Immune System Pathway  366160!!Antigen Processing: Ubiquitination   Proteasome Degradation Pathway  366162!!Class I MHC Mediated Antigen Processing   Presentation Pathway  366161!!Immune System Pathway  106386!!TWEAK Signaling Pathway  672452
ncbi summary : 
This gene encodes a member of the RING zinc finger protein family found in striated muscle and iris. The product of this gene is an E3 ubiquitin ligase that localizes to the Z-line and M-line lattices of myofibrils. This protein plays an important role in the atrophy of skeletal and cardiac muscle and is required for the degradation of myosin heavy chain proteins, myosin light chain, myosin binding protein, and for muscle-type creatine kinase. [provided by RefSeq, Feb 2012]