Rabbit Polyclonal to Human WNT8B / Wnt 8b | MyBioSource MBS241513 product information

product summary

company name :

MyBioSource

product type :

antibody

product name :

Rabbit Polyclonal to Human WNT8B / Wnt 8b

catalog :

MBS241513

quantity :

0.05 mg

price :

495 USD

clonality :

polyclonal

host :

rabbit

conjugate :

nonconjugated

reactivity :

human, mouse, rat, dog, cow

application :

immunohistochemistry, immunohistochemistry - paraffin section

more info or order :

MyBioSource product webpage

product information

catalog number :

MBS241513

products type :

Antibody

products full name :

Rabbit Polyclonal to Human WNT8B / Wnt 8b

products short name :

WNT8B / Wnt 8b

products name syn :

Anti-WNT8B / Wnt 8b Antibody (Internal) IHC-plus; WNT8B; Protein Wnt-8b; WNT 8b; Human WNT8B; Wnt 8b

other names :

protein Wnt-8b; Protein Wnt-8b; protein Wnt-8b; wingless-type MMTV integration site family, member 8B

products gene name :

WNT8B

products gene name syn :

Wnt 8b

other gene names :

WNT8B; WNT8B

uniprot entry name :

WNT8B_HUMAN

clonality :

Polyclonal

host :

Rabbit

reactivity :

Human, Monkey, Mouse, Rat, Bat, Bovine, Dog, Hamster, Horse, Pig, Rabbit

sequence length :

351

specificity :

Human WNT8B. BLAST analysis of the peptide immunogen showed no homology with other human proteins.

purity :

Immunoaffinity Purified

form :

PBS, less than 0.1% sodium azide.

concentration :

1 mg/ml

storage stability :

Upon arrival: Aliquot and store undiluted at -20 degree C or below for up to 1 year. Can be stored undiluted at 4 degree C for up to 1 month. Avoid freeze thaw cycles.

tested application :

Immunohistochemistry (IHC - Paraffin)

app notes :

IHC-P (10 ug/ml). Usage: Immunohistochemistry:MBS241513 was validated for use in immunohistochemistry on a panel of 21 formalin-fixed, paraffin-embedded (FFPE) human tissues after heat induced antigen retrieval in pH 6.0 citrate buffer. After incubation with the primary antibody, slides were incubated with biotinylated secondary antibody, followed by alkaline phosphatase-streptavidin and chromogen. The stained slides were evaluated by a pathologist to confirm staining specificity. The optimal working concentration for MBS241513 was determined to be 10 ug/ml.

other info1 :

Family/Subfamily: WNT/not assigned-WNT. Target Species: Human. Immunogen Description: Synthetic 16 amino acid peptide from internal region of human WNT8B. Percent identity with other species by BLAST analysis: Human, Gorilla, Gibbon, Monkey, Mouse, Rat, Dog, Bovine, Bat, Hamster, Elephant, Panda, Horse, Rabbit, Pig (100%).

other info2 :

Immunogen Type: Synthetic peptide. Immunogen: WNT8B / Wnt 8b antibody was raised against synthetic 16 amino acid peptide from internal region of human WNT8B. Percent identity with other species by BLAST analysis: Human, Gorilla, Gibbon, Monkey, Mouse, Rat, Dog, Bovine, Bat, Hamster, Elephant, Panda, Horse, Rabbit, Pig (100%); Opossum, Platypus (94%); Marmoset (88%). Antigen Modification: Internal

products categories :

Family: WNT

products description :

The WNT gene family consists of structurally related genes which encode secreted signaling proteins. These proteins have been implicated in oncogenesis and in several developmental processes, including regulation of cell fate and patterning during embryogenesis. This gene is a member of the WNT gene family. It encodes a protein which shows 95%, 86% and 71% amino acid identity to the mouse, zebrafish and Xenopus Wnt8B proteins, respectively. The expression patterns of the human and mouse genes appear identical and are restricted to the developing brain. The chromosomal location of this gene to 10q24 suggests it as a candidate gene for partial epilepsy.

ncbi gi num :

110735437

ncbi acc num :

NP_003384.2

ncbi gb acc num :

NM_003393.3

uniprot acc num :

Q93098

ncbi mol weight :

38,721 Da

ncbi pathways :

Basal Cell Carcinoma Pathway (83113); Basal Cell Carcinoma Pathway (525); Class B/2 (Secretin Family Receptors) Pathway (106378); Defective ACTH Causes Obesity And Pro-opiomelanocortinin Deficiency (POMCD) Pathway (1127664); Disease Pathway (530764); GPCR Ligand Binding Pathway (161020); HTLV-I Infection Pathway (373901); HTLV-I Infection Pathway (373889); Hedgehog Signaling Pathway (83063); Hedgehog Signaling Pathway (474)

ncbi summary :

uniprot summary :

WNT8B: Ligand for members of the frizzled family of seven transmembrane receptors. May play an important role in the development and differentiation of certain forebrain structures, notably the hippocampus. Belongs to the Wnt family. Protein type: Secreted, signal peptide; Secreted. Chromosomal Location of Human Ortholog: 10q24. Cellular Component: extracellular space; proteinaceous extracellular matrix; extracellular region. Molecular Function: frizzled binding. Biological Process: neuron differentiation; nervous system development; cell fate commitment; response to retinoic acid; Wnt receptor signaling pathway; gastrulation; determination of dorsal identity; signal transduction; response to estradiol stimulus

size1 :

0.05 mg

price1 :

495 USD

more info or order :

MyBioSource product webpage