catalog number :
MBS241445
products full name :
Rabbit Polyclonal (IgG) to Human RPS6 / S6
products short name :
RPS6 / S6
products name syn :
Anti-RPS6 / S6 Antibody (Ser235) IHC-plus; RPS6; 40S ribosomal protein S6; S6; Ribosomal protein S6; Phosphoprotein NP33; Human RPS6; S6
other names :
40S ribosomal protein S6; 40S ribosomal protein S6; 40S ribosomal protein S6; phosphoprotein NP33; ribosomal protein S6; Phosphoprotein NP33
products gene name :
RPS6
products gene name syn :
S6
other gene names :
RPS6; RPS6; S6
uniprot entry name :
RS6_HUMAN
reactivity :
Human, Mouse, Rat
specificity :
Amino acids surrounding Ser 235 of human RPS6
purity :
Immunoaffinity Purified
form :
PBS, 0.02% sodium azide, 50% glycerol.
storage stability :
Long term: -70 degree C; Short term: -20 degree C
tested application :
Immunohistochemistry (IHC - Paraffin), Immunofluorescence (IF), Western Blot (WB)
app notes :
IF, IHC-P (10 ug/ml), WB. Usage: Immunohistochemistry: was validated for use in immunohistochemistry on a panel of 21 formalin-fixed, paraffin-embedded (FFPE) human tissues after heat induced antigen retrieval in pH 6.0 citrate buffer. After incubation with the primary anti.
other info1 :
Target Species: Human. Immunogen Description: Synthetic peptide from human RPS6.
other info2 :
Immunogen Type: Synthetic peptide. Immunogen: RPS6 / S6 antibody was raised against synthetic peptide from human RPS6. Antigen Modification: Ser235
ncbi acc num :
NP_001001.2
ncbi gb acc num :
NM_001010.2
ncbi mol weight :
28,681 Da
ncbi pathways :
Activation Of The MRNA Upon Binding Of The Cap-binding Complex And EIFs, And Subsequent Binding To 43S Pathway 105970!!B Cell Receptor Signaling Pathway 198909!!BDNF Signaling Pathway 712093!!Cap-dependent Translation Initiation Pathway 105967!!Cytoplasmic Ribosomal Proteins Pathway 198853!!Disease Pathway 530764!!ErbB1 Downstream Signaling Pathway 138057!!Eukaryotic Translation Elongation Pathway 105976!!Eukaryotic Translation Initiation Pathway 105966!!Eukaryotic Translation Termination Pathway 105978
ncbi summary :
Ribosomes, the organelles that catalyze protein synthesis, consist of a small 40S subunit and a large 60S subunit. Together these subunits are composed of 4 RNA species and approximately 80 structurally distinct proteins. This gene encodes a cytoplasmic ribosomal protein that is a component of the 40S subunit. The protein belongs to the S6E family of ribosomal proteins. It is the major substrate of protein kinases in the ribosome, with subsets of five C-terminal serine residues phosphorylated by different protein kinases. Phosphorylation is induced by a wide range of stimuli, including growth factors, tumor-promoting agents, and mitogens. Dephosphorylation occurs at growth arrest. The protein may contribute to the control of cell growth and proliferation through the selective translation of particular classes of mRNA. As is typical for genes encoding ribosomal proteins, there are multiple processed pseudogenes of this gene dispersed through the genome. [provided by RefSeq, Jul 2008]