Rabbit Polyclonal to Human LPAR4 / GPR23 | MyBioSource MBS241437 product information

product summary

company name :

MyBioSource

product type :

antibody

product name :

Rabbit Polyclonal to Human LPAR4 / GPR23

catalog :

MBS241437

quantity :

0.05 mg

price :

495 USD

clonality :

polyclonal

host :

rabbit

conjugate :

nonconjugated

reactivity :

human, mouse, rat

application :

immunohistochemistry, immunohistochemistry - paraffin section

more info or order :

MyBioSource product webpage

product information

catalog number :

MBS241437

products type :

Antibody

products full name :

Rabbit Polyclonal to Human LPAR4 / GPR23

products short name :

LPAR4 / GPR23

products name syn :

Anti-LPAR4 / GPR23 Antibody (C-Terminus) IHC-plus; LPAR4; G-protein coupled receptor 23; LPA-4; p2RY9; p2Y5-LIKE; p2Y purinoceptor 9; p2Y5-like receptor; p2Y9; G protein-coupled receptor 23; GPR23; LPA receptor 4; LPA4; Purinergic receptor 9; Human LPAR4; GPR23

other names :

lysophosphatidic acid receptor 4; Lysophosphatidic acid receptor 4; lysophosphatidic acid receptor 4; LPA-4; LPA receptor 4; P2Y purinoceptor 9; P2Y5-like receptor; purinergic receptor 9; G protein-coupled receptor 23; G-protein coupled receptor 23; lysophosphatidic acid receptor 4; G-protein coupled receptor 23; P2Y purinoceptor 9; P2Y9; P2Y5-like receptor; Purinergic receptor 9

products gene name :

LPAR4

products gene name syn :

GPR23

other gene names :

LPAR4; LPAR4; LPA4; P2Y9; GPR23; P2RY9; P2Y5-LIKE; GPR23; LPA4; P2RY9; LPA receptor 4; LPA-4; P2Y9

uniprot entry name :

LPAR4_HUMAN

clonality :

Polyclonal

host :

Rabbit

reactivity :

Gorilla, Human. Predicted Reactivity: Gibbon, Monkey, Mouse, Rat, Bat, Hamster, Pig, Rabbit (at least 90% immunogen sequence identity)

sequence length :

370

specificity :

Human LPAR4 / GPR23. BLAST analysis of the peptide immunogen showed no homology with other human proteins.

purity :

Immunoaffinity Purified

form :

PBS, 0.1% sodium azide.

concentration :

1 mg/ml

storage stability :

Long term: -70 degree C; Short term: +4 degree C

tested application :

Immunohistochemistry (IHC - Paraffin)

app notes :

IHC-P (5 - 10 ug/ml). Usage: Immunohistochemistry: was validated for use in immunohistochemistry on a panel of 21 formalin-fixed, paraffin-embedded (FFPE) human tissues after heat induced antigen retrieval in pH 6.0 citrate buffer. After incubation with the primary antib.

other info1 :

Target Species: Human. Immunogen Description: Synthetic 17 amino acid peptide from C-terminal cytoplasmic domain of human LPAR4 / GPR23. Percent identity with other species by BLAST analysis: Human, Gorilla (100%); Gibbon, Marmoset, Mouse, Rat, Bat, Hamster, Rabbit, Pig (94%).

other info2 :

Immunogen Type: Synthetic peptide. Immunogen: LPAR4 / GPR23 antibody was raised against synthetic 17 amino acid peptide from C-terminal cytoplasmic domain of human LPAR4 / GPR23. Percent identity with other species by BLAST analysis: Human, Gorilla (100%); Gibbon, Marmoset, Mouse, Rat, Bat, Hamster, Rabbit, Pig (94%); Monkey, Bovine, Panda, Horse (88%); Dog, Elephant (82%). Antigen Modification: C-Terminus

products categories :

Family: GPCR. Subfamily: Lysophospholipid/Lysosphingolipid

products description :

GPR23 has been identified as a Lysophospholipid/Lysosphingolipid Receptor.

ncbi gi num :

4885311

ncbi acc num :

NP_005287.1

ncbi gb acc num :

NM_005296.2

uniprot acc num :

Q99677

ncbi mol weight :

41,895 Da

ncbi pathways :

Class A/1 (Rhodopsin-like Receptors) Pathway (106357); Defective ACTH Causes Obesity And Pro-opiomelanocortinin Deficiency (POMCD) Pathway (1127664); Disease Pathway (530764); G Alpha (q) Signalling Events Pathway (106043); GPCR Downstream Signaling Pathway (119548); GPCR Ligand Binding Pathway (161020); GPCRs, Class A Rhodopsin-like Pathway (198886); Gastrin-CREB Signalling Pathway Via PKC And MAPK (645295); LPA Receptor Mediated Events Pathway (137928); LPA4-mediated Signaling Events Pathway (137949)

ncbi summary :

This gene encodes a member of the lysophosphatidic acid receptor family. It may also be related to the P2Y receptors, a family of receptors that bind purine and pyrimidine nucleotides and are coupled to G proteins. The encoded protein may play a role in monocytic differentiation. [provided by RefSeq, Feb 2009]

uniprot summary :

LPAR4: Receptor for lysophosphatidic acid (LPA), a mediator of diverse cellular activities. Transduces a signal by increasing the intracellular calcium ions and by stimulating adenylyl cyclase activity. The rank order of potency for agonists of this receptor is 1-oleoyl- 1-stearoyl- 1-palmitoyl- 1-myristoyl- 1- alkyl- 1-alkenyl-LPA. Belongs to the G-protein coupled receptor 1 family. Protein type: Membrane protein, multi-pass; Receptor, GPCR; Membrane protein, integral; GPCR, family 1. Chromosomal Location of Human Ortholog: Xq21.1. Cellular Component: integral to plasma membrane; plasma membrane. Molecular Function: G-protein coupled receptor activity; lipid binding. Biological Process: G-protein coupled receptor protein signaling pathway

size1 :

0.05 mg

price1 :

495 USD

more info or order :

MyBioSource product webpage