catalog number :
MBS241399
products full name :
Rabbit Polyclonal (IgG) to Human YWHAZ / 14-3-3 Zeta
products short name :
YWHAZ / 14-3-3 Zeta
products name syn :
Anti-YWHAZ / 14-3-3 Zeta Antibody (Ser58) IHC-plus; YWHAZ; 14-3-3 protein zeta/delta; 14-3-3-zeta; 14-3-3 delta; 14-3-3 protein zeta; 14-3-3 zeta; Phospholipase A2; YWHAD; KCIP-1; Human YWHAZ; 14-3-3 Zeta
other names :
14-3-3 protein zeta/delta; 14-3-3 protein zeta/delta; 14-3-3 protein zeta/delta; 14-3-3 zeta; 14-3-3 delta; phospholipase A2; epididymis luminal protein 4; epididymis secretory protein Li 3; protein kinase C inhibitor protein 1; protein kinase C inhibitor protein-1; 14-3-3 protein/cytosolic phospholipase A2; tyrosine 3/tryptophan 5 -monooxygenase activation protein, zeta polypeptide; tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, zeta polypeptide; tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, delta polypeptide; tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, zeta; Protein kinase C inhibitor protein 1; KCIP-1
products gene name :
YWHAZ
other gene names :
YWHAZ; YWHAZ; HEL4; YWHAD; KCIP-1; HEL-S-3; 14-3-3-zeta; KCIP-1
uniprot entry name :
1433Z_HUMAN
reactivity :
Human, Mouse, Rat
specificity :
Amino acids surrounding Ser 58 of human YWHAZ
purity :
Immunoaffinity Purified
form :
PBS, 0.02% sodium azide, 50% glycerol.
storage stability :
+4 degree C or -20 degree C, Avoid repeated freezing and thawing.
tested application :
Immunohistochemistry (IHC - Paraffin), Western Blot (WB)
app notes :
IHC-P (10 ug/ml), WB. Usage: Immunohistochemistry: was validated for use in immunohistochemistry on a panel of 21 formalin-fixed, paraffin-embedded (FFPE) human tissues after heat induced antigen retrieval in pH 6.0 citrate buffer. After incubation with the primary anti.
other info1 :
Target Species: Human. Immunogen Description: Synthetic peptide from human YWHAZ / Phospholipase A2.
other info2 :
Immunogen Type: Synthetic peptide. Immunogen: YWHAZ / 14-3-3 Zeta antibody was raised against synthetic peptide from human YWHAZ / Phospholipase A2. Antigen Modification: Ser58
products categories :
Family: Phospholipase
products description :
This gene product belongs to the 14-3-3 family of proteins which mediate signal transduction by binding to phosphoserine-containing proteins. This highly conserved protein family is found in both plants and mammals, and this protein is 99% identical to the mouse, rat and sheep orthologs. The encoded protein interacts with IRS1 protein, suggesting a role in regulating insulin sensitivity.
ncbi acc num :
NP_003397.1
ncbi gb acc num :
NM_003406.3
ncbi mol weight :
19,333 Da
ncbi pathways :
Activation Of BAD And Translocation To Mitochondria Pathway 105659!!Activation Of BH3-only Proteins Pathway 105658!!Adaptive Immune System Pathway 366160!!Alpha6-Beta4 Integrin Signaling Pathway 198807!!Apoptosis Pathway 105648!!Calcium Regulation In The Cardiac Cell Pathway 198906!!Cell Cycle Pathway 198811!!Cell Cycle Pathway 83054!!Cell Cycle Pathway 463!!Class I PI3K Signaling Events Mediated By Akt Pathway 138020
ncbi summary :
This gene product belongs to the 14-3-3 family of proteins which mediate signal transduction by binding to phosphoserine-containing proteins. This highly conserved protein family is found in both plants and mammals, and this protein is 99% identical to the mouse, rat and sheep orthologs. The encoded protein interacts with IRS1 protein, suggesting a role in regulating insulin sensitivity. Several transcript variants that differ in the 5' UTR but that encode the same protein have been identified for this gene. [provided by RefSeq, Oct 2008]