This webpage contains legacy information. The product is either no longer available from the supplier or has been delisted at Labome.
product summary
company name :
MyBioSource
product type :
antibody
product name :
Rabbit Polyclonal (IgG) to Human CREB1 / CREB
catalog :
MBS241375
quantity :
0.05 mg
price :
495 USD
clonality :
polyclonal
host :
rabbit
conjugate :
nonconjugated
reactivity :
human, mouse, rat
application :
western blot, immunohistochemistry
product information
catalog number :
MBS241375
products type :
Antibody
products full name :
Rabbit Polyclonal (IgG) to Human CREB1 / CREB
products short name :
CREB1 / CREB
products name syn :
Anti-CREB1 / CREB Antibody (Ser133) IHC-plus; CREB1; CREB-1; Transactivator protein; CREB; Human CREB1; CREB
other names :
cyclic AMP-responsive element-binding protein 1 isoform A; Cyclic AMP-responsive element-binding protein 1; cyclic AMP-responsive element-binding protein 1; CREB-1; transactivator protein; active transcription factor CREB; cAMP-response element-binding protein-1; cAMP-responsive element-binding protein 1; cAMP responsive element binding protein 1
products gene name :
CREB1
products gene name syn :
CREB
other gene names :
CREB1; CREB1; CREB; CREB-1; cAMP-responsive element-binding protein 1
uniprot entry name :
CREB1_HUMAN
clonality :
Polyclonal
isotype :
IgG
host :
Rabbit
reactivity :
Human, Mouse, Rat
sequence length :
327
specificity :
Amino acids surrounding Ser 133 of human CREB1
purity :
Immunoaffinity Purified
form :
PBS, 0.02% sodium azide, 50% glycerol.
storage stability :
Long term: -70 degree C; Short term: -20 degree C
tested application :
Immunohistochemistry (IHC - Paraffin), Western Blot (WB)
app notes :
IHC-P (10 ug/ml), WB (1:500 - 1:1000). Usage: Immunohistochemistry: was validated for use in immunohistochemistry on a panel of 21 formalin-fixed, paraffin-embedded (FFPE) human tissues after heat induced antigen retrieval in pH 6.0 citrate buffer. After incubation with the primary anti.
other info1 :
Target Species: Human. Immunogen Description: Synthetic peptide from human CREB1 / CREB.
other info2 :
Immunogen Type: Synthetic peptide. Immunogen: CREB1 / CREB antibody was raised against synthetic peptide from human CREB1 / CREB. Antigen Modification: Ser133
products categories :
Family: Transcription factor
products description :
CREB (cAMP response element binding protein1), a DNA binding protein, is a member of the leucine zipper family of transcription factors. CREB interaction with DNA requires phosphorylation at Ser 119 by activated cAMP protein kinase A. Once phosphorylated CREB binds to an 8 base enhancer know as the cAMP response element (CRE) containing a conserved core sequence TGACG. CREB also interacts with CBP (CREB binding protein) and RNA polymerase II when phosphorylated on Ser 133.
ncbi gi num :
4758054
ncbi acc num :
NP_004370.1
ncbi gb acc num :
NM_004379.3
uniprot acc num :
P16220
ncbi mol weight :
25,445 Da
ncbi pathways :
AKT Phosphorylates Targets In The Nucleus Pathway 106476!!AMPK Signaling Pathway 989139!!AMPK Signaling Pathway 992181!!ATF-2 Transcription Factor Network Pathway 138006!!ATM Signaling Pathway 920969!!Activated TLR4 Signalling Pathway 106400!!Activation Of NMDA Receptor Upon Glutamate Binding And Postsynaptic Events Pathway 161033!!Adaptive Immune System Pathway 366160!!Adipogenesis Pathway 198832!!Adrenergic Signaling In Cardiomyocytes Pathway 908257
ncbi summary :
This gene encodes a transcription factor that is a member of the leucine zipper family of DNA binding proteins. This protein binds as a homodimer to the cAMP-responsive element, an octameric palindrome. The protein is phosphorylated by several protein kinases, and induces transcription of genes in response to hormonal stimulation of the cAMP pathway. Alternate splicing of this gene results in two transcript variants encoding different isoforms. [provided by RefSeq, Jul 2008]
size :
0.05 mg
price :
495 USD
company information
MyBioSource
P.O. Box 153308
San Diego, CA 92195-3308
sales@mybiosource.com
https://www.mybiosource.com
1-888-627-0165
headquarters: USA
MyBioSource, LLC was orginally founded in Vancouver by three enthusiastic scientists who are passionate about providing the world with the best reagents available. Together, they form a company with a big vision known as MyBioSource. MyBioSource is now located in San Diego, California, USA.

"MyBioSource's number 1 vision is to be the world's number 1 quality reagents provider."

Our goal is to provide researchers, scientists and customers alike with a one-stop-shop for all of their reagents needs, whether it is monoclonal antibody, polyclonal antibody, recombinant protein, peptide, etc...

"MyBioSource offers the best products at unbeatable prices."

Please spend a few minutes to browse our online catalogs and see the wide range of products available. We ship our products through our shipping/distribution facility in San Diego, California, USA.

Would you like to receive email and e-newsletter from MyBioSource about new products, special offers and events? Please click here to join our Mailing List!