catalog number :
MBS241337
products full name :
Rabbit Polyclonal (IgG) to Human ORAI2
products short name :
ORAI2
products name syn :
Anti-ORAI2 Antibody (C-Terminus) IHC-plus; ORAI2; C7orf19; CBCIP2; MEM142B; Protein orai-2; TMEM142B; Transmembrane protein 142B; Putative protein ORAI2-2; H_NH0514P08.8; Human ORAI2
other names :
protein orai-2 isoform a; Protein orai-2; protein orai-2; H_NH0514P08.8; putative protein ORAI2-2; transmembrane protein 142B; CAP-binding protein complex interacting protein 2; CAP-binding protein complex-interacting protein 2; ORAI calcium release-activated calcium modulator 2; CAP-binding protein complex-interacting protein 2; Transmembrane protein 142B
products gene name :
ORAI2
other gene names :
ORAI2; ORAI2; CBCIP2; C7orf19; MEM142B; TMEM142B; C7orf19; CBCIP2; TMEM142B
uniprot entry name :
ORAI2_HUMAN
reactivity :
Human, Mouse
specificity :
An 15 amino acid peptide from near the carboxy terminus of humAn ORAI2
purity :
Immunoaffinity Purified
form :
PBS, 0.02% sodium azide.
storage stability :
Short term 4 degree C, long term aliquot and store at -20 degree C, avoid freeze thaw cycles. Store undiluted.
tested application :
Immunohistochemistry (IHC - Paraffin), Western Blot (WB)
app notes :
IHC-P (5 ug/ml), WB (2 ug/ml). Usage: Immunohistochemistry: was validated for use in immunohistochemistry on a panel of 21 formalin-fixed, paraffin-embedded (FFPE) human tissues after heat induced antigen retrieval in pH 6.0 citrate buffer. After incubation with the primary anti.
other info1 :
Target Species: Human. Immunogen Description: Synthetic peptide from human ORAI2.
other info2 :
Immunogen Type: Synthetic peptide. Immunogen: ORAI2 antibody was raised against synthetic peptide from human ORAI2. Antigen Modification: C-Terminus. Usage Summary: Immunohistochemistry: MBS241337 was validated for use in immunohistochemistry on a panel of 21 formalin-fixed, paraffin-embedded (FFPE) human tissues after heat induced antigen retrieval in pH 6.0 citrate buffer. After incubation with the primary antibody, slides were incubated with biotinylated secondary antibody, followed by alkaline phosphatase-streptavidin and chromogen. The stained slides were evaluated by a pathologist to confirm staining specificity. The optimal working concentration for MBS241337 was determined to be 5 ug/ml.
ncbi acc num :
NP_116220.1
ncbi gb acc num :
NM_032831.3
ncbi mol weight :
28,570 Da
ncbi pathways :
Calcium Signaling Pathway (83050); Calcium Signaling Pathway (459)
uniprot summary :
TMEM142B: Ca(2+) release-activated Ca(2+)-like (CRAC-like) channel subunit which mediates Ca(2+) influx and increase in Ca(2+)- selective current by synergy with the Ca(2+) sensor, STIM1. Belongs to the Orai family. Protein type: Membrane protein, integral; Membrane protein, multi-pass. Chromosomal Location of Human Ortholog: 7q22.1. Cellular Component: growth cone; integral to membrane. Molecular Function: protein binding