This webpage contains legacy information. The product is either no longer available from the supplier or has been delisted at Labome.
product summary
company name :
MyBioSource
product type :
antibody
product name :
Rabbit Polyclonal (IgG) to Human BCL2L1 / BCL-XL
catalog :
MBS241140
quantity :
0.05 mg
price :
495 USD
clonality :
polyclonal
host :
rabbit
conjugate :
nonconjugated
reactivity :
human, mouse, rat
application :
western blot, immunohistochemistry
product information
catalog number :
MBS241140
products type :
Antibody
products full name :
Rabbit Polyclonal (IgG) to Human BCL2L1 / BCL-XL
products short name :
BCL2L1 / BCL-XL
products name syn :
Anti-BCL2L1 / BCL-XL Antibody (Ser62) IHC-plus; BCL2L1; Apoptosis regulator Bcl-X; Bcl-xL; BCL-XL/S; BCLXS; Bcl-2-like protein 1; BCL2-like 1; BCL2L; Bcl-X; Bcl-xS; BCLXL; PPP1R52; Bcl2-L-1; BCLX; Human BCL2L1; BCL-XL
other names :
bcl-2-like protein 1 isoform 2; Bcl-2-like protein 1; bcl-2-like protein 1; apoptosis regulator Bcl-X; protein phosphatase 1, regulatory subunit 52; BCL2-like 1; Apoptosis regulator Bcl-X
products gene name :
BCL2L1
products gene name syn :
BCL-XL
other gene names :
BCL2L1; BCL2L1; BCLX; BCL2L; BCLXL; BCLXS; Bcl-X; bcl-xL; bcl-xS; PPP1R52; BCL-XL/S; BCL2L; BCLX; Bcl2-L-1
uniprot entry name :
B2CL1_HUMAN
clonality :
Polyclonal
isotype :
IgG
host :
Rabbit
reactivity :
Human, Mouse, Rat
sequence length :
170
specificity :
Amino acids surrounding Serine 62 of human BCL2L1
purity :
Immunoaffinity Purified
form :
PBS, 0.02% sodium azide, 50% glycerol.
storage stability :
Long term: -70 degree C; Short term: -20 degree C
tested application :
Immunohistochemistry (IHC - Paraffin), Western Blot (WB)
app notes :
IHC-P (10 ug/ml), WB. Usage: Immunohistochemistry: was validated for use in immunohistochemistry on a panel of 21 formalin-fixed, paraffin-embedded (FFPE) human tissues after heat induced antigen retrieval in pH 6.0 citrate buffer. After incubation with the primary anti.
other info1 :
Target Species: Human. Immunogen Description: Synthetic peptide from human BCL2L1 / Bcl-xL.
other info2 :
Immunogen Type: Synthetic peptide. Immunogen: BCL2L1 / BCL-XL antibody was raised against synthetic peptide from human BCL2L1 / Bcl-xL. Antigen Modification: Ser62
products categories :
Family: Apoptosis
products description :
Apoptosis plays a major role in normal organism development, tissue homeostasis, and removal of damaged cells. Disruption of this process has been implicated in a variety of diseases such as cancer. Bcl-xL is a member of the Bcl-2 family of proteins that are critical regulators of apoptosis. These can be divided into two classes: those that inhibit apoptosis and those that promote cell death.
ncbi gi num :
4502381
ncbi acc num :
NP_001182.1
ncbi gb acc num :
NM_001191.2
uniprot acc num :
Q07817
ncbi mol weight :
25,290 Da
ncbi pathways :
Amyotrophic Lateral Sclerosis (ALS) Pathway 920975!!Amyotrophic Lateral Sclerosis (ALS) Pathway 83099!!Amyotrophic Lateral Sclerosis (ALS) Pathway 511!!Apoptosis Pathway 198797!!Apoptosis Pathway 83060!!Apoptosis Pathway 470!!Apoptosis Pathway 105648!!Apoptosis Modulation And Signaling Pathway 198822!!BH3-only Proteins Associate With And Inactivate Anti-apoptotic BCL-2 Members Pathway 105664!!Chronic Myeloid Leukemia Pathway 83116
ncbi summary :
The protein encoded by this gene belongs to the BCL-2 protein family. BCL-2 family members form hetero- or homodimers and act as anti- or pro-apoptotic regulators that are involved in a wide variety of cellular activities. The proteins encoded by this gene are located at the outer mitochondrial membrane, and have been shown to regulate outer mitochondrial membrane channel (VDAC) opening. VDAC regulates mitochondrial membrane potential, and thus controls the production of reactive oxygen species and release of cytochrome C by mitochondria, both of which are the potent inducers of cell apoptosis. Two alternatively spliced transcript variants, which encode distinct isoforms, have been reported. The longer isoform acts as an apoptotic inhibitor and the shorter form acts as an apoptotic activator. [provided by RefSeq, Jul 2008]
size :
0.05 mg
price :
495 USD
company information
MyBioSource
P.O. Box 153308
San Diego, CA 92195-3308
sales@mybiosource.com
https://www.mybiosource.com
1-888-627-0165
headquarters: USA
MyBioSource, LLC was orginally founded in Vancouver by three enthusiastic scientists who are passionate about providing the world with the best reagents available. Together, they form a company with a big vision known as MyBioSource. MyBioSource is now located in San Diego, California, USA.

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