This webpage contains legacy information. The product is either no longer available from the supplier or has been delisted at Labome.
product summary
company name :
MyBioSource
product type :
antibody
product name :
Rabbit Polyclonal (IgG) to Human BCL2 / Bcl-2
catalog :
MBS241139
quantity :
0.05 mg
price :
495 USD
clonality :
polyclonal
host :
rabbit
conjugate :
nonconjugated
reactivity :
human
application :
western blot, immunohistochemistry, immunocytochemistry
product information
catalog number :
MBS241139
products type :
Antibody
products full name :
Rabbit Polyclonal (IgG) to Human BCL2 / Bcl-2
products short name :
BCL2 / Bcl-2
products name syn :
Anti-BCL2 / Bcl-2 Antibody (Ser70) IHC-plus; BCL2; Apoptosis regulator Bcl-2; B-cell CLL/lymphoma 2; B-cell lymphoma protein 2; Bcl-2; PPP1R50; Human BCL2; Bcl-2
other names :
apoptosis regulator Bcl-2 alpha isoform; Apoptosis regulator Bcl-2; apoptosis regulator Bcl-2; protein phosphatase 1, regulatory subunit 50; B-cell CLL/lymphoma 2
products gene name :
BCL2
products gene name syn :
Bcl-2
other gene names :
BCL2; BCL2; Bcl-2; PPP1R50
uniprot entry name :
BCL2_HUMAN
clonality :
Polyclonal
isotype :
IgG
host :
Rabbit
reactivity :
Human
sequence length :
239
specificity :
Amino acids surrounding Serine 70 of human BCL2
purity :
Immunoaffinity Purified
form :
PBS, 0.02% sodium azide, 50% glycerol.
concentration :
1 mg/ml
storage stability :
+4 degree C or -20 degree C, Avoid repeated freezing and thawing.
tested application :
Immunohistochemistry (IHC - Paraffin), Immunofluorescence (IF), Western Blot (WB)
app notes :
IF, IHC-P (10 ug/ml), WB. Usage: Immunohistochemistry: was validated for use in immunohistochemistry on a panel of 21 formalin-fixed, paraffin-embedded (FFPE) human tissues after heat induced antigen retrieval in pH 6.0 citrate buffer. After incubation with the primary anti.
other info1 :
Target Species: Human. Immunogen Description: Synthetic peptide from human BCL2 / Bcl-2.
other info2 :
Immunogen Type: Synthetic peptide. Immunogen: BCL2 / Bcl-2 antibody was raised against synthetic peptide from human BCL2 / Bcl-2. Antigen Modification: Ser70
products categories :
Family: Apoptosis
products description :
Bcl-2 inhibits apoptosis. Translocations that lead to overexpression of this gene are associated with cancer (lymphoma in the case of translocation to the Ig heavy chain locus).
ncbi gi num :
72198189
ncbi acc num :
NP_000624.2
ncbi gb acc num :
NM_000633.2
uniprot acc num :
P10415
ncbi mol weight :
22,337 Da
ncbi pathways :
ATF-2 Transcription Factor Network Pathway 138006!!Activation Of BAD And Translocation To Mitochondria Pathway 105659!!Activation Of BH3-only Proteins Pathway 105658!!Adrenergic Signaling In Cardiomyocytes Pathway 908257!!Adrenergic Signaling In Cardiomyocytes Pathway 909696!!Amyotrophic Lateral Sclerosis (ALS) Pathway 920975!!Amyotrophic Lateral Sclerosis (ALS) Pathway 83099!!Amyotrophic Lateral Sclerosis (ALS) Pathway 511!!Apoptosis Pathway 198797!!Apoptosis Pathway 83060
ncbi summary :
This gene encodes an integral outer mitochondrial membrane protein that blocks the apoptotic death of some cells such as lymphocytes. Constitutive expression of BCL2, such as in the case of translocation of BCL2 to Ig heavy chain locus, is thought to be the cause of follicular lymphoma. Two transcript variants, produced by alternate splicing, differ in their C-terminal ends. [provided by RefSeq, Jul 2008]
size :
0.05 mg
price :
495 USD
company information
MyBioSource
P.O. Box 153308
San Diego, CA 92195-3308
sales@mybiosource.com
https://www.mybiosource.com
1-888-627-0165
headquarters: USA
MyBioSource, LLC was orginally founded in Vancouver by three enthusiastic scientists who are passionate about providing the world with the best reagents available. Together, they form a company with a big vision known as MyBioSource. MyBioSource is now located in San Diego, California, USA.

"MyBioSource's number 1 vision is to be the world's number 1 quality reagents provider."

Our goal is to provide researchers, scientists and customers alike with a one-stop-shop for all of their reagents needs, whether it is monoclonal antibody, polyclonal antibody, recombinant protein, peptide, etc...

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