This webpage contains legacy information. The product is either no longer available from the supplier or has been delisted at Labome.
product summary
company name :
MyBioSource
product type :
antibody
product name :
Rabbit Polyclonal (IgG) to Human AKT1 / AKT
catalog :
MBS241133
quantity :
0.05 mg
price :
495 USD
clonality :
polyclonal
host :
rabbit
conjugate :
nonconjugated
reactivity :
human, mouse, rat
application :
western blot, immunohistochemistry
product information
catalog number :
MBS241133
products type :
Antibody
products full name :
Rabbit Polyclonal (IgG) to Human AKT1 / AKT
products short name :
AKT1 / AKT
products name syn :
Anti-AKT1 / AKT Antibody (Thr308) IHC-plus; AKT1; AKT; AKT-1; C-AKT; Pan-AKT; PKB alpha; PKBalpha; Proto-oncogene c-Akt; Protein kinase B; Rac protein kinase alpha; PRKBA; Protein kinase B alpha; RAC-PK-alpha; PKB; PKB-ALPHA; RAC; RAC-ALPHA; Human AKT1; AKT
other names :
RAC-alpha serine/threonine-protein kinase; RAC-alpha serine/threonine-protein kinase; RAC-alpha serine/threonine-protein kinase; AKT1m; PKB alpha; RAC-PK-alpha; proto-oncogene c-Akt; protein kinase B alpha; rac protein kinase alpha; v-akt murine thymoma viral oncogene homolog 1; Protein kinase B; PKB; Protein kinase B alpha; PKB alpha; Proto-oncogene c-Akt; RAC-PK-alpha
products gene name :
AKT1
products gene name syn :
AKT
other gene names :
AKT1; AKT1; AKT; PKB; RAC; CWS6; PRKBA; PKB-ALPHA; RAC-ALPHA; PKB; RAC; PKB; PKB alpha
uniprot entry name :
AKT1_HUMAN
clonality :
Polyclonal
isotype :
IgG
host :
Rabbit
reactivity :
Human, Mouse, Rat
sequence length :
480
specificity :
Amino acids surrounding threonine 308 of human AKT
purity :
Immunoaffinity Purified
form :
PBS, 0.02% sodium azide, 50% glycerol.
concentration :
1 mg/ml
storage stability :
Long term: -70 degree C; Short term: -20 degree C
tested application :
Immunohistochemistry (IHC - Paraffin), Western Blot (WB)
app notes :
IHC-P (20 ug/ml), WB. Usage: Immunohistochemistry: was validated for use in immunohistochemistry on a panel of 21 formalin-fixed, paraffin-embedded (FFPE) human tissues after heat induced antigen retrieval in pH 6.0 citrate buffer. After incubation with the primary anti.
other info1 :
Target Species: Human. Immunogen Description: Synthetic peptide from human AKT1.
other info2 :
Immunogen Type: Synthetic peptide. Immunogen: AKT1 / AKT antibody was raised against synthetic peptide from human AKT1. Antigen Modification: Thr308
products categories :
Family: Protein Kinase. Subfamily: RAC/AKT
products description :
AKT1 encodes a RAC/AKT -type protein kinase that contains a N-terminal pleckstrin-homology (PH) domain and a central catalytic domain closely related to both cAMP-dependent protein kinase and protein kinase C. The protein is a member of PI3K-mediated signaling pathways associated with the regulation of proliferation, survival, protein synthesis, and metabolism.
ncbi gi num :
62241011
ncbi acc num :
NP_005154.2
ncbi gb acc num :
NM_005163.2
uniprot acc num :
P31749
ncbi mol weight :
48,347 Da
ncbi pathways :
AGE/RAGE Pathway 698754!!AKT Phosphorylates Targets In The Cytosol Pathway 106475!!AKT Phosphorylates Targets In The Nucleus Pathway 106476!!AKT-mediated Inactivation Of FOXO1A Pathway 106333!!AMPK Signaling Pathway 198868!!AMPK Signaling Pathway 989139!!AMPK Signaling Pathway 992181!!Activation Of BAD And Translocation To Mitochondria Pathway 105659!!Activation Of BH3-only Proteins Pathway 105658!!Acute Myeloid Leukemia Pathway 83117
ncbi summary :
The serine-threonine protein kinase encoded by the AKT1 gene is catalytically inactive in serum-starved primary and immortalized fibroblasts. AKT1 and the related AKT2 are activated by platelet-derived growth factor. The activation is rapid and specific, and it is abrogated by mutations in the pleckstrin homology domain of AKT1. It was shown that the activation occurs through phosphatidylinositol 3-kinase. In the developing nervous system AKT is a critical mediator of growth factor-induced neuronal survival. Survival factors can suppress apoptosis in a transcription-independent manner by activating the serine/threonine kinase AKT1, which then phosphorylates and inactivates components of the apoptotic machinery. Mutations in this gene have been associated with the Proteus syndrome. Multiple alternatively spliced transcript variants have been found for this gene. [provided by RefSeq, Jul 2011]
size :
0.05 mg
price :
495 USD
company information
MyBioSource
P.O. Box 153308
San Diego, CA 92195-3308
sales@mybiosource.com
https://www.mybiosource.com
1-888-627-0165
headquarters: USA
MyBioSource, LLC was orginally founded in Vancouver by three enthusiastic scientists who are passionate about providing the world with the best reagents available. Together, they form a company with a big vision known as MyBioSource. MyBioSource is now located in San Diego, California, USA.

"MyBioSource's number 1 vision is to be the world's number 1 quality reagents provider."

Our goal is to provide researchers, scientists and customers alike with a one-stop-shop for all of their reagents needs, whether it is monoclonal antibody, polyclonal antibody, recombinant protein, peptide, etc...

"MyBioSource offers the best products at unbeatable prices."

Please spend a few minutes to browse our online catalogs and see the wide range of products available. We ship our products through our shipping/distribution facility in San Diego, California, USA.

Would you like to receive email and e-newsletter from MyBioSource about new products, special offers and events? Please click here to join our Mailing List!