catalog number :
MBS241036
products full name :
Rabbit Polyclonal to Human MVP / LRP
products short name :
MVP / LRP
products name syn :
Anti-MVP / LRP Antibody (aa878-893) IHC-plus; MVP; Major vault protein; VAULT1; LRP; Human MVP; LRP
other names :
major vault protein isoform 1; Major vault protein; major vault protein; lung resistance-related protein; major vault protein; Lung resistance-related protein
products gene name syn :
LRP
other gene names :
MVP; MVP; LRP; VAULT1; LRP; MVP
uniprot entry name :
MVP_HUMAN
specificity :
Amino acids 878-893 of human MVP
purity :
Protein G Purified
form :
PBS, 0.1% sodium azide.
storage stability :
Long term: -20 degree C; Short term: +4 degree C. Avoid repeat freeze-thaw cycles.
tested application :
Immunohistochemistry (IHC - Paraffin), ELISA (EIA)
app notes :
ELISA (1:000 - 1:1000), IHC-P (10 ug/ml). Usage: Immunohistochemistry: was validated for use in immunohistochemistry on a panel of 21 formalin-fixed, paraffin-embedded (FFPE) human tissues after heat induced antigen retrieval in pH 6.0 citrate buffer. After incubation with the primary antib.
other info1 :
Target Species: Human. Immunogen Description: Synthetic peptide from human MVP.
other info2 :
Immunogen Type: Synthetic peptide. Immunogen: MVP / LRP antibody was raised against synthetic peptide from human MVP. Antigen Modification: aa878-893
ncbi acc num :
NP_059447.2
ncbi gb acc num :
NM_017458.3
ncbi mol weight :
99,327 Da
ncbi summary :
This gene encodes the major component of the vault complex. Vaults are multi-subunit ribonucleoprotein structures that may be involved in nucleo-cytoplasmic transport. The encoded protein may play a role in multiple cellular processes by regulating the MAP kinase, JAK/STAT and phosphoinositide 3-kinase/Akt signaling pathways. The encoded protein also plays a role in multidrug resistance, and expression of this gene may be a prognostic marker for several types of cancer. Alternatively spliced transcript variants have been observed for this gene. [provided by RefSeq, May 2012]