catalog number :
MBS240907
products full name :
Rabbit Polyclonal to Human HTR1E / 5-HT1E Receptor
products short name :
HTR1E / 5-HT1E Receptor
products name syn :
Anti-HTR1E / 5-HT1E Receptor Antibody (Cytoplasmic Domain) IHC-plus; HTR1E; 5-HT1E; 5-HT1e receptor; 5-HT-1E; 5HT1E Receptor; HT1e receptor; S31; Serotonin 5-HT-1e receptor; Serotonin 1e receptor; Serotonin receptor 1E; Human HTR1E; 5-HT1E Receptor
other names :
5-hydroxytryptamine receptor 1E; 5-hydroxytryptamine receptor 1E; 5-hydroxytryptamine receptor 1E; S31; 5-HT-1E; serotonin receptor 1E; 5-hydroxytryptamine (serotonin) receptor 1E, G protein-coupled; S31; Serotonin receptor 1E
products gene name :
HTR1E
other gene names :
HTR1E; HTR1E; 5-HT1E; 5-HT-1E; 5-HT1E
uniprot entry name :
5HT1E_HUMAN
reactivity :
Bat, Chimpanzee, Guinea pig, Gorilla, Horse, Human, Monkey. Predicted Reactivity: Orangutan, Gibbon, Bovine (at least 90% immunogen sequence identity)
specificity :
Human 5HT1E Receptor. BLAST analysis of the peptide immunogen showed no homology with other human proteins.
purity :
Immunoaffinity Purified
form :
PBS, 0.1% sodium azide.
storage stability :
Long term: -70 degree C; Short term: +4 degree C
tested application :
Immunohistochemistry (IHC - Paraffin), ELISA (EIA)
app notes :
ELISA, IHC-P (16 - 24 ug/ml). Usage: Immunohistochemistry: was validated for use in immunohistochemistry on a panel of 21 formalin-fixed, paraffin-embedded (FFPE) human tissues after heat induced antigen retrieval in pH 6.0 citrate buffer. After incubation with the primary anti.
other info1 :
Target Species: Human. Immunogen Description: Synthetic 19 amino acid peptide from 3rd cytoplasmic domain of human 5HT1E Receptor. Percent identity with other species by BLAST analysis: Human, Chimpanzee, Gorilla, Monkey, Bat, Elephant, Horse, Guinea pig (100%); Orangutan, Gibbon, Bovine (95%).
other info2 :
Immunogen Type: Synthetic peptide. Immunogen: HTR1E / 5-HT1E Receptor antibody was raised against synthetic 19 amino acid peptide from 3rd cytoplasmic domain of human 5HT1E Receptor. Percent identity with other species by BLAST analysis: Human, Chimpanzee, Gorilla, Monkey, Bat, Elephant, Horse, Guinea pig (100%); Orangutan, Gibbon, Bovine (95%); Panda (89%); Opossum (84%). Antigen Modification: Cytoplasmic Domain
products categories :
Family: GPCR. Subfamily: Serotonin
products description :
5HT1E, a Serotonin Receptor, is not well studied. It is classified as an 5-HT1-like receptor because of its ligand-binding and effector-coupling characteristics. The human 5-HT1E receptor has been studied in an African green monkey kidney cell line, in which it modulated cAMP levels upon binding serotonin. Lack of structural variants in the human gene indicate a highly conserved protein.
ncbi acc num :
NP_000856.1
ncbi gb acc num :
NM_000865.2
ncbi mol weight :
41,682 Da
ncbi pathways :
Amine Ligand-binding Receptors Pathway 106363!!Class A/1 (Rhodopsin-like Receptors) Pathway 106357!!Defective ACTH Causes Obesity And Pro-opiomelanocortinin Deficiency (POMCD) Pathway 1127664!!Disease Pathway 530764!!G Alpha (i) Signalling Events Pathway 119550!!GPCR Downstream Signaling Pathway 119548!!GPCR Ligand Binding Pathway 161020!!GPCRs, Class A Rhodopsin-like Pathway 198886!!Metabolic Disorders Of Biological Oxidation Enzymes Pathway 1127637!!Monoamine GPCRs Pathway 198861