product summary
Loading...
company name :
MyBioSource
product type :
antibody
product name :
Rabbit Polyclonal to Human GPR124 / TEM5
catalog :
MBS240897
quantity :
0.05 mg
price :
495 USD
clonality :
polyclonal
host :
rabbit
conjugate :
nonconjugated
reactivity :
human
application :
immunohistochemistry, immunohistochemistry - paraffin section
more info or order :
product information
catalog number :
MBS240897
products type :
Antibody
products full name :
Rabbit Polyclonal to Human GPR124 / TEM5
products short name :
GPR124 / TEM5
products name syn :
Anti-GPR124 / TEM5 Antibody (N-Terminus) IHC-plus; GPR124; G protein-coupled receptor 124; G-protein coupled receptor 124; TEM5; KIAA1531; Tumor endothelial marker 5; Human GPR124; TEM5
other names :
probable G-protein coupled receptor 124; G-protein coupled receptor 124; G-protein coupled receptor 124; tumor endothelial marker 5; G protein-coupled receptor 124; Tumor endothelial marker 5
products gene name :
GPR124
products gene name syn :
TEM5
other gene names :
GPR124; GPR124; TEM5; KIAA1531; TEM5
uniprot entry name :
GP124_HUMAN
clonality :
Polyclonal
host :
Rabbit
reactivity :
Gorilla, Human. Predicted Reactivity: Gibbon, Monkey (at least 90% immunogen sequence identity)
sequence length :
1338
specificity :
Human GPR124. BLAST analysis of the peptide immunogen showed no homology with other human proteins, except SEMA4G (55%), CSF3 (40%).
purity :
Immunoaffinity Purified
form :
PBS, 0.1% sodium azide.
concentration :
0.9 mg/ml
storage stability :
Long term: -70 degree C; Short term: +4 degree C
tested application :
Immunohistochemistry (IHC - Paraffin)
app notes :
IHC-P (11 ug/ml). Usage: Immunohistochemistry: was validated for use in immunohistochemistry on a panel of 21 formalin-fixed, paraffin-embedded (FFPE) human tissues after heat induced antigen retrieval in pH 6.0 citrate buffer. After incubation with the primary anti.
other info1 :
Target Species: Human. Immunogen Description: Synthetic 20 amino acid peptide from N-terminal extracellular domain of human GPR124. Percent identity with other species by BLAST analysis: Human, Gorilla (100%); Gibbon, Monkey (90%); Dog (85%).
other info2 :
Immunogen Type: Synthetic peptide. Immunogen: GPR124 / TEM5 antibody was raised against synthetic 20 amino acid peptide from N-terminal extracellular domain of human GPR124. Percent identity with other species by BLAST analysis: Human, Gorilla (100%); Gibbon, Monkey (90%); Dog (85%). Antigen Modification: N-Terminus
products categories :
Family: GPCR. Subfamily: Orphan-U
products description :
Tumor endothelial marker 5 is an Orphan-U GPCR with an unknown ligand. Tumor Endothelial Marker 5, like GPR125, has a leucine rich repeat (LRR), an immunoglobulin (Ig) domain, and a hormone-binding domain (HBD). The Ig domain shows similarities to motilin and titin, while the LRR domain shows similarities to LRIG1 and SLIT1-2.
ncbi gi num :
194272183
ncbi acc num :
NP_116166.7
ncbi gb acc num :
NM_032777.7
uniprot acc num :
Q96PE1
ncbi mol weight :
19,530 Da
ncbi pathways :
Integrins In Angiogenesis Pathway (137999)
uniprot summary :
GPR124: Endothelial receptor that acts as an essential regulator of CNS angiogenesis. Required for normal endothelial cell sprouting and migration in the forebrain and neural tube. Belongs to the G-protein coupled receptor 2 family. LN-TM7 subfamily. 3 isoforms of the human protein are produced by alternative splicing. Protein type: Receptor, GPCR; Membrane protein, integral; GPCR, family 2; Membrane protein, multi-pass. Chromosomal Location of Human Ortholog: 8p11.23. Cellular Component: cell surface; integral to membrane; plasma membrane. Molecular Function: G-protein coupled receptor activity. Biological Process: G-protein coupled receptor protein signaling pathway; central nervous system development; regulation of chemotaxis; endothelial cell migration; sprouting angiogenesis; regulation of angiogenesis
size1 :
0.05 mg
price1 :
495 USD
more info or order :
company information
MyBioSource
P.O. Box 153308
San Diego, CA 92195-3308
San Diego, CA 92195-3308
sales@mybiosource.com
https://www.mybiosource.com1-888-627-0165
headquarters: USA
MyBioSource, LLC was orginally founded in Vancouver by three enthusiastic scientists who are passionate about providing the world with the best reagents available. Together, they form a company with a big vision known as MyBioSource. MyBioSource is now located in San Diego, California, USA.
"MyBioSource's number 1 vision is to be the world's number 1 quality reagents provider."
Our goal is to provide researchers, scientists and customers alike with a one-stop-shop for all of their reagents needs, whether it is monoclonal antibody, polyclonal antibody, recombinant protein, peptide, etc...
"MyBioSource offers the best products at unbeatable prices."
Please spend a few minutes to browse our online catalogs and see the wide range of products available. We ship our products through our shipping/distribution facility in San Diego, California, USA.
Would you like to receive email and e-newsletter from MyBioSource about new products, special offers and events? Please click here to join our Mailing List!
browse more products
questions and comments