This webpage contains legacy information. The product is either no longer available from the supplier or has been delisted at Labome.
product summary
company name :
MyBioSource
product type :
antibody
product name :
Rabbit Polyclonal to Human PAK6
catalog :
MBS240879
quantity :
0.05 mg
price :
495 USD
clonality :
polyclonal
host :
rabbit
conjugate :
nonconjugated
reactivity :
human, mouse, rat, dog, chicken, cow
application :
immunohistochemistry, enzyme immunoassay
product information
catalog number :
MBS240879
products type :
Antibody
products full name :
Rabbit Polyclonal to Human PAK6
products short name :
PAK6
products name syn :
Anti-PAK6 Antibody (N-Terminus) IHC-plus; PAK6; PAK5; p21-activated kinase 6; p21-activated protein kinase 6; PAK-5; PAK-6; p21(CDKN1A)-activated kinase 6; Human PAK6
other names :
serine/threonine-protein kinase PAK 6 isoform 1; Serine/threonine-protein kinase PAK 6; serine/threonine-protein kinase PAK 6; p21(CDKN1A)-activated kinase 6; p21 protein (Cdc42/Rac)-activated kinase 6; PAK-5; p21-activated kinase 6; PAK-6
products gene name :
PAK6
other gene names :
PAK6; PAK6; PAK5; PAK5; PAK-6
uniprot entry name :
PAK6_HUMAN
clonality :
Polyclonal
host :
Rabbit
reactivity :
Bat, Gibbon, Bovine, Chicken, Dog, Gorilla, Horse, Human, Monkey, Mouse, Orangutan, Rabbit, Rat. Predicted Reactivity: Xenopus (at least 90% immunogen sequence identity)
sequence length :
681
specificity :
Human PAK6. BLAST analysis of the peptide immunogen showed no homology with other human proteins, except PAK7 (69%).
purity :
Immunoaffinity Purified
form :
PBS, 0.1% sodium azide.
concentration :
1 mg/ml
storage stability :
Long term: -70 degree C; Short term: +4 degree C
tested application :
Immunohistochemistry (IHC - Paraffin), ELISA (EIA)
app notes :
ELISA, IHC-P (10 ug/ml). Usage: Immunohistochemistry: was validated for use in immunohistochemistry on a panel of 21 formalin-fixed, paraffin-embedded (FFPE) human tissues after heat induced antigen retrieval in pH 6.0 citrate buffer. After incubation with the primary anti.
other info1 :
Target Species: Human. Immunogen Description: Synthetic 16 amino acid peptide from N-terminus of human PAK6.
other info2 :
Immunogen Type: Synthetic peptide. Immunogen: PAK6 antibody was raised against synthetic 16 amino acid peptide from N-terminus of human PAK6. Percent identity with other species by BLAST analysis: Human, Gorilla, Orangutan, Gibbon, Monkey, Marmoset, Mouse, Rat, Bovine, Dog, Bat, Elephant, Panda, Horse, Rabbit, Sparrow, Chicken, Platypus (100%); Xenopus (94%); Goat (88%). Antigen Modification: N-Terminus
products categories :
Family: Protein Kinase. Subfamily: PAK (STE20)
products description :
PAK6, a PAK (STE20) type protein kinase, contains a N-terminal Cdc42/Rac interactive binding (CRIB) motif and a C-terminal kinase domain. The protein has been shown to bind to GTP-Cdc42 and GTP-Rac; however, in contrast to most PAKs, kinase activity was not stimulated by Cdc42 or Rac, but could be stimulated by androgen receptor (AR) binding. PAK6 protein also has been shown to bind to estrogen receptor alpha.
ncbi gi num :
9910476
ncbi acc num :
NP_064553.1
ncbi gb acc num :
NM_020168.5
uniprot acc num :
Q9NQU5
ncbi mol weight :
69,777 Da
ncbi pathways :
Activation Of Rac Pathway 119530!!Androgen Receptor Signaling Pathway 198806!!Axon Guidance Pathway 83065!!Axon Guidance Pathway 476!!Axon Guidance Pathway 105688!!Developmental Biology Pathway 477129!!ErbB Signaling Pathway 83049!!ErbB Signaling Pathway 458!!Focal Adhesion Pathway 198795!!Focal Adhesion Pathway 83067
ncbi summary :
This gene encodes a member of a family of p21-stimulated serine/threonine protein kinases, which contain an amino-terminal Cdc42/Rac interactive binding (CRIB) domain and a carboxyl-terminal kinase domain. These kinases function in a number of cellular processes, including cytoskeleton rearrangement, apoptosis, and the mitogen-activated protein (MAP) kinase signaling pathway. The protein encoded by this gene interacts with androgen receptor (AR) and translocates to the nucleus, where it is involved in transcriptional regulation. Changes in expression of this gene have been linked to prostate cancer. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Mar 2013]
size :
0.05 mg
price :
495 USD
company information
MyBioSource
P.O. Box 153308
San Diego, CA 92195-3308
sales@mybiosource.com
https://www.mybiosource.com
1-888-627-0165
headquarters: USA
MyBioSource, LLC was orginally founded in Vancouver by three enthusiastic scientists who are passionate about providing the world with the best reagents available. Together, they form a company with a big vision known as MyBioSource. MyBioSource is now located in San Diego, California, USA.

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