This webpage contains legacy information. The product is either no longer available from the supplier or has been delisted at Labome.
product summary
company name :
MyBioSource
product type :
antibody
product name :
Rabbit Polyclonal to Human MTOR
catalog :
MBS240649
quantity :
0.05 mg
price :
495 USD
clonality :
polyclonal
host :
rabbit
conjugate :
nonconjugated
reactivity :
human
application :
western blot, ELISA, immunohistochemistry, enzyme immunoassay
product information
catalog number :
MBS240649
products type :
Antibody
products full name :
Rabbit Polyclonal to Human MTOR
products short name :
MTOR
products name syn :
Anti-MTOR Antibody (phospho-Ser2448) IHC-plus; MTOR; FRAP1; FRAP2; FRAP; Mammalian target of rapamycin; RAFT1; Rapamycin and FKBP12 target 1; RAPT1; Rapamycin target protein 1; Human MTOR
other names :
serine/threonine-protein kinase mTOR; Serine/threonine-protein kinase mTOR; serine/threonine-protein kinase mTOR; rapamycin target protein 1; mammalian target of rapamycin; rapamycin and FKBP12 target 1; FKBP-rapamycin associated protein; rapamycin associated protein FRAP2; FKBP12-rapamycin complex-associated protein 1; FK506 binding protein 12-rapamycin associated protein 2; FK506-binding protein 12-rapamycin complex-associated protein 1; mechanistic target of rapamycin (serine/threonine kinase); FK506-binding protein 12-rapamycin complex-associated protein 1; FKBP12-rapamycin complex-associated protein; Mammalian target of rapamycin; mTOR; Mechanistic target of rapamycin; Rapamycin and FKBP12 target 1; Rapamycin target protein 1
products gene name :
MTOR
other gene names :
MTOR; MTOR; FRAP; FRAP1; FRAP2; RAFT1; RAPT1; FRAP; FRAP1; FRAP2; RAFT1; RAPT1; mTOR
uniprot entry name :
MTOR_HUMAN
clonality :
Polyclonal
host :
Rabbit
reactivity :
Human
sequence length :
2549
specificity :
Amino acids 2440-2457 of human mTOR.
purity :
Immunoaffinity Purified
form :
0.02 M potassium phosphate, 0.15 M sodium chloride, pH 7.2, 0.01% sodium azide.
concentration :
1 mg/ml
storage stability :
Store vial at -20 degree C prior to opening. Dilute only prior to immediate use. For extended storage aliquot contents and freeze at -20 degree C or below. Avoid cycles of freezing and thawing.
tested application :
Immunohistochemistry (IHC - Paraffin), Western Blot (WB), ELISA (EIA)
app notes :
ELISA (1:15000 - 1:65000), IHC-P (5 ug/ml), WB (1:500 - 1:2000). Usage: Immunohistochemistry: was validated for use in immunohistochemistry on a panel of 21 formalin-fixed, paraffin-embedded (FFPE) human tissues after heat induced antigen retrieval in pH 6.0 citrate buffer. After incubation with the primary antibo.
other info1 :
Target Species: Human. Immunogen Description: Synthetic peptide from human mTOR.
other info2 :
Immunogen Type: Synthetic peptide. Immunogen: MTOR antibody was raised against synthetic peptide from human mTOR. Antigen Modification: pSer2448
products categories :
Family: Protein Kinase. Subfamily: PI3/PI4
products description :
The mammalian Target of Rapamycin (TOR, also known as mTOR) is an evolutionarily conserved serine/threonine kinase that regulates cell growth and cell cycle through its ability to integrate signals from nutrient levels and growth factors. It was initially discovered as a kinase whose ability to stimulate T cell proliferation in response to IL-2 could be inhibited by the immunosuppressive drug rapamycin.
ncbi gi num :
4826730
ncbi acc num :
NP_004949.1
ncbi gb acc num :
NM_004958.3
uniprot acc num :
P42345
ncbi mol weight :
288,892 Da
ncbi pathways :
AMPK Signaling Pathway 198868!!AMPK Signaling Pathway 989139!!AMPK Signaling Pathway 992181!!Acute Myeloid Leukemia Pathway 83117!!Acute Myeloid Leukemia Pathway 529!!Adaptive Immune System Pathway 366160!!Adipocytokine Signaling Pathway 83093!!Adipocytokine Signaling Pathway 505!!Alpha6-Beta4 Integrin Signaling Pathway 198807!!BDNF Signaling Pathway 712093
ncbi summary :
The protein encoded by this gene belongs to a family of phosphatidylinositol kinase-related kinases. These kinases mediate cellular responses to stresses such as DNA damage and nutrient deprivation. This protein acts as the target for the cell-cycle arrest and immunosuppressive effects of the FKBP12-rapamycin complex. The ANGPTL7 gene is located in an intron of this gene. [provided by RefSeq, Sep 2008]
size :
0.05 mg
price :
495 USD
company information
MyBioSource
P.O. Box 153308
San Diego, CA 92195-3308
sales@mybiosource.com
https://www.mybiosource.com
1-888-627-0165
headquarters: USA
MyBioSource, LLC was orginally founded in Vancouver by three enthusiastic scientists who are passionate about providing the world with the best reagents available. Together, they form a company with a big vision known as MyBioSource. MyBioSource is now located in San Diego, California, USA.

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