This webpage contains legacy information. The product is either no longer available from the supplier or has been delisted at Labome.
product summary
company name :
MyBioSource
product type :
antibody
product name :
Sheep Polyclonal to Human HCRT / Orexin
catalog :
MBS240638
quantity :
0.05 ml
price :
495 USD
clonality :
polyclonal
host :
sheep
conjugate :
nonconjugated
reactivity :
human, mouse, rat, dog, cow, Rhesus monkey
application :
immunohistochemistry, enzyme immunoassay
product information
catalog number :
MBS240638
products type :
Antibody
products full name :
Sheep Polyclonal to Human HCRT / Orexin
products short name :
HCRT / Orexin
products name syn :
Anti-HCRT / Orexin Antibody IHC-plus; HCRT; PPORX; OX; Hypocretin; NRCLP1; Orexin; Human HCRT; Orexin
other names :
orexin; Orexin; orexin; prepro-orexin; hypocretin (orexin) neuropeptide precursor; Hypocretin; Hcrt
products gene name :
HCRT
other gene names :
HCRT; HCRT; OX; PPOX; NRCLP1; OX; PPORX; PPOX; Hcrt; Hcrt1; Hcrt2
uniprot entry name :
OREX_HUMAN
clonality :
Polyclonal
host :
Sheep
reactivity :
Human. Predicted Reactivity: Chimpanzee, Mouse, Rat, Bovine, Dog, Horse, Pig, Rabbit, Rhesus monkey (at least 90% immunogen sequence identity)
sequence length :
131
specificity :
Specific for human orexin A.
purity :
Affinity Purified
form :
PBS, pH 7.2, 0.09% sodium azide.
concentration :
8 mg/ml
storage stability :
+4 degree C or -20 degree C, Avoid repeated freezing and thawing.
tested application :
Immunohistochemistry (IHC - Paraffin; IHC - Frozen), ELISA (EIA)
app notes :
ELISA, IHC-Fr, IHC-P (10 ug/ml). Usage: Immunohistochemistry: was validated for use in immunohistochemistry on a panel of 21 formalin-fixed, paraffin-embedded (FFPE) human tissues after heat induced antigen retrieval in pH 6.0 citrate buffer. After incubation with the primary antibo.
other info1 :
Target Species: Human. Immunogen Description: Synthetic peptide, PLPDCCRQKTCSC, corresponding to amino acids 2-14 of human orexin A conjugated to KLH.
other info2 :
Immunogen Type: Synthetic peptide. Immunogen: HCRT / Orexin antibody was raised against synthetic peptide, PLPDCCRQKTCSC, corresponding to amino acids 2-14 of human orexin A conjugated to KLH.
products description :
Orexin, or hypocretin (HCRT), is a hypothalamic neuropeptide precursor protein that gives rise to two mature neuropeptides, orexin A and orexin B, by proteolytic processing. Orexin A and orexin B, which bind to orphan G-protein coupled receptors HCRTR1 and HCRTR2, are mediators in the central feedback mechanism that regulates feeding behavior.
ncbi gi num :
4557635
ncbi acc num :
NP_001515.1
ncbi gb acc num :
NM_001524.1
uniprot acc num :
O43612
ncbi mol weight :
13,363 Da
ncbi pathways :
Class A/1 (Rhodopsin-like Receptors) Pathway 106357!!Defective ACTH Causes Obesity And Pro-opiomelanocortinin Deficiency (POMCD) Pathway 1127664!!Disease Pathway 530764!!G Alpha (q) Signalling Events Pathway 106043!!GPCR Downstream Signaling Pathway 119548!!GPCR Ligand Binding Pathway 161020!!Gastrin-CREB Signalling Pathway Via PKC And MAPK 645295!!Metabolic Disorders Of Biological Oxidation Enzymes Pathway 1127637!!Orexin And Neuropeptides FF And QRFP Bind To Their Respective Receptors Pathway 106362!!Peptide Ligand-binding Receptors Pathway 106358
ncbi summary :
This gene encodes a hypothalamic neuropeptide precursor protein that gives rise to two mature neuropeptides, orexin A and orexin B, by proteolytic processing. Orexin A and orexin B, which bind to orphan G-protein coupled receptors HCRTR1 and HCRTR2, function in the regulation of sleep and arousal. This neuropeptide arrangement may also play a role in feeding behavior, metabolism, and homeostasis. [provided by RefSeq, Jan 2010]
size :
0.05 ml
price :
495 USD
company information
MyBioSource
P.O. Box 153308
San Diego, CA 92195-3308
sales@mybiosource.com
https://www.mybiosource.com
1-888-627-0165
headquarters: USA
MyBioSource, LLC was orginally founded in Vancouver by three enthusiastic scientists who are passionate about providing the world with the best reagents available. Together, they form a company with a big vision known as MyBioSource. MyBioSource is now located in San Diego, California, USA.

"MyBioSource's number 1 vision is to be the world's number 1 quality reagents provider."

Our goal is to provide researchers, scientists and customers alike with a one-stop-shop for all of their reagents needs, whether it is monoclonal antibody, polyclonal antibody, recombinant protein, peptide, etc...

"MyBioSource offers the best products at unbeatable prices."

Please spend a few minutes to browse our online catalogs and see the wide range of products available. We ship our products through our shipping/distribution facility in San Diego, California, USA.

Would you like to receive email and e-newsletter from MyBioSource about new products, special offers and events? Please click here to join our Mailing List!