This webpage contains legacy information. The product is either no longer available from the supplier or has been delisted at Labome.
product summary
company name :
MyBioSource
product type :
antibody
product name :
Rabbit Polyclonal to Human RELA / NFKB p65
catalog :
MBS240395
quantity :
0.05 mg
price :
495 USD
clonality :
polyclonal
host :
rabbit
conjugate :
nonconjugated
reactivity :
human
application :
western blot, ELISA, immunohistochemistry, enzyme immunoassay
product information
catalog number :
MBS240395
products type :
Antibody
products full name :
Rabbit Polyclonal to Human RELA / NFKB p65
products short name :
RELA / NFKB p65
products name syn :
Anti-RELA / NFKB p65 Antibody IHC-plus; RELA; NF-kappa-B p65delta3; NFKB3; p65; Transcription factor p65; Human RELA; NFKB p65
other names :
transcription factor p65 isoform 1; Transcription factor p65; transcription factor p65; NF-kappa-B p65delta3; nuclear factor NF-kappa-B p65 subunit; v-rel reticuloendotheliosis viral oncogene homolog A; nuclear factor of kappa light polypeptide gene enhancer in B-cells 3; v-rel avian reticuloendotheliosis viral oncogene homolog A; Nuclear factor NF-kappa-B p65 subunit; Nuclear factor of kappa light polypeptide gene enhancer in B-cells 3
products gene name :
RELA
products gene name syn :
NFKB
other gene names :
RELA; RELA; p65; NFKB3; NFKB3
uniprot entry name :
TF65_HUMAN
clonality :
Polyclonal
host :
Rabbit
reactivity :
Human
sequence length :
551
specificity :
Residues surrounding S536 of human p65 (RelA) protein.
purity :
Immunoaffinity Purified
form :
0.02 M potassium phosphate, 0.15 M sodium chloride, pH 7.2, 0.01% sodium azide.
concentration :
1 mg/ml
storage stability :
+4 degree C or -20 degree C, Avoid repeated freezing and thawing.
tested application :
Immunohistochemistry (IHC - Paraffin), Western Blot (WB), ELISA (EIA)
app notes :
ELISA (1:1000 - 1:6000), IHC-P (5 ug/ml), WB (1:200 - 1:2000). Usage: Immunohistochemistry: was validated for use in immunohistochemistry on a panel of 21 formalin-fixed, paraffin-embedded (FFPE) human tissues after heat induced antigen retrieval in pH 6.0 citrate buffer. After incubation with the primary antibo.
other info1 :
Target Species: Human. Immunogen Description: Synthetic peptide from human RELA.
other info2 :
Immunogen Type: Synthetic peptide. Immunogen: RELA / NFKB p65 antibody was raised against synthetic peptide from human RELA.
products description :
NFKB1 or NFKB2 bind to REL, RELA, or RELB to form the NFKB complex. The NFKB1/RELA heterodimer is the most abundant form of NFKB. The NFKB complex is inactivated by I-kappa-B proteins that keep it trapped in the cytoplasm. Phosphorylation of serine residues on the I-kappa B proteins mark them for ubiquitination and destruction, and NFKB translocates to the nucleus where it binds DNA.
ncbi gi num :
223468676
ncbi acc num :
NP_068810.3
ncbi gb acc num :
NM_021975.3
uniprot acc num :
Q04206
ncbi mol weight :
59,910 Da
ncbi pathways :
AGE/RAGE Pathway 698754!!Activated TLR4 Signalling Pathway 106400!!Activation Of NF-kappaB In B Cells Pathway 576251!!Acute Myeloid Leukemia Pathway 83117!!Acute Myeloid Leukemia Pathway 529!!Adaptive Immune System Pathway 366160!!Adipocytokine Signaling Pathway 83093!!Adipocytokine Signaling Pathway 505!!Amoebiasis Pathway 167324!!Amoebiasis Pathway 167191
ncbi summary :
NF-kappa-B is a ubiquitous transcription factor involved in several biological processes. It is held in the cytoplasm in an inactive state by specific inhibitors. Upon degradation of the inhibitor, NF-kappa-B moves to the nucleus and activates transcription of specific genes. NF-kappa-B is composed of NFKB1 or NFKB2 bound to either REL, RELA, or RELB. The most abundant form of NF-kappa-B is NFKB1 complexed with the product of this gene, RELA. Four transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Sep 2011]
size :
0.05 mg
price :
495 USD
company information
MyBioSource
P.O. Box 153308
San Diego, CA 92195-3308
sales@mybiosource.com
https://www.mybiosource.com
1-888-627-0165
headquarters: USA
MyBioSource, LLC was orginally founded in Vancouver by three enthusiastic scientists who are passionate about providing the world with the best reagents available. Together, they form a company with a big vision known as MyBioSource. MyBioSource is now located in San Diego, California, USA.

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