catalog number :
MBS240389
products full name :
Rabbit Polyclonal to Human NRN1 / Neuritin
products short name :
NRN1 / Neuritin
products name syn :
Anti-NRN1 / Neuritin Antibody (Internal) IHC-plus; NRN1; Neuritin 1; NRN; DJ380B8.2; Neuritin; Human NRN1; Neuritin
other names :
neuritin isoform 1; Neuritin; neuritin; neuritin 1
products gene name :
NRN1
other gene names :
NRN1; NRN1; NRN; dJ380B8.2; NRN
uniprot entry name :
NRN1_HUMAN
reactivity :
Human, Mouse
specificity :
20 amino acid peptide from near the center of human neuritin.
purity :
Immunoaffinity Purified
form :
PBS, 0.02% sodium azide.
storage stability :
Short term 4 degree C, long term aliquot and store at -20 degree C, avoid freeze thaw cycles. Store undiluted.
tested application :
Immunohistochemistry (IHC - Paraffin), Western Blot (WB)
app notes :
IHC-P (10 ug/ml), WB. Usage: Immunohistochemistry: was validated for use in immunohistochemistry on a panel of 21 formalin-fixed, paraffin-embedded (FFPE) human tissues after heat induced antigen retrieval in pH 6.0 citrate buffer. After incubation with the primary antib.
other info1 :
Target Species: Human. Immunogen Description: Synthetic peptide from human NRN1 / Neuritin.
other info2 :
Immunogen Type: Synthetic peptide. Immunogen: NRN1 / Neuritin antibody was raised against synthetic peptide from human NRN1 / Neuritin. Antigen Modification: Internal
ncbi acc num :
NP_057672.1
ncbi gb acc num :
NM_016588.2
ncbi mol weight :
15,333 Da
ncbi summary :
This gene encodes a member of the neuritin family, and is expressed in postmitotic-differentiating neurons of the developmental nervous system and neuronal structures associated with plasticity in the adult. The expression of this gene can be induced by neural activity and neurotrophins. The encoded protein contains a consensus cleavage signal found in glycosylphoshatidylinositol (GPI)-anchored proteins. The encoded protein promotes neurite outgrowth and arborization, suggesting its role in promoting neuritogenesis. Overexpression of the encoded protein may be associated with astrocytoma progression. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Jul 2013]
uniprot summary :
NRN1: Promotes neurite outgrowth and especially branching of neuritic processes in primary hippocampal and cortical cells. Belongs to the neuritin family. Protein type: Membrane protein, GPI anchor. Chromosomal Location of Human Ortholog: 6p25.1. Cellular Component: plasma membrane; synapse; cell junction. Biological Process: nervous system development