This webpage contains legacy information. The product is either no longer available from the supplier or has been delisted at Labome.
product summary
company name :
MyBioSource
product type :
antibody
product name :
Rabbit Polyclonal to Human Tuberin / TSC2
catalog :
MBS240302
quantity :
0.05 mg
price :
495 USD
clonality :
polyclonal
host :
rabbit
conjugate :
nonconjugated
reactivity :
human, mouse
application :
western blot, immunohistochemistry, immunocytochemistry
product information
catalog number :
MBS240302
products type :
Antibody
products full name :
Rabbit Polyclonal to Human Tuberin / TSC2
products short name :
Tuberin / TSC2
products name syn :
Anti-Tuberin / TSC2 Antibody (N-Terminus) IHC-plus; TSC2; LAM; Tuberous sclerosis 2 protein; TSC4; Tuberin; Tuberous sclerosis 2; Human Tuberin; TSC2
other names :
tuberin isoform 1; Tuberin; tuberin; tuberous sclerosis 2 protein; protein phosphatase 1, regulatory subunit 160; tuberous sclerosis 2; Tuberous sclerosis 2 protein
products gene name :
TSC2
other gene names :
TSC2; TSC2; LAM; TSC4; PPP1R160; TSC4
uniprot entry name :
TSC2_HUMAN
clonality :
Polyclonal
host :
Rabbit
reactivity :
Human, Mouse
sequence length :
1807
specificity :
14 amino acid peptide from near the amino terminus of human TSC2
purity :
Immunoaffinity Purified
form :
PBS, 0.02% sodium azide.
concentration :
1 mg/ml
storage stability :
Short term 4 degree C, long term aliquot and store at -20 degree C, avoid freeze thaw cycles. Store undiluted.
tested application :
Immunohistochemistry (IHC - Paraffin), Immunocytochemistry (ICC), Western Blot (WB)
app notes :
ICC, IHC-P (5 ug/ml), WB (1 ug/ml). Usage: Immunohistochemistry: was validated for use in immunohistochemistry on a panel of 21 formalin-fixed, paraffin-embedded (FFPE) human tissues after heat induced antigen retrieval in pH 6.0 citrate buffer. After incubation with the primary antib.
other info1 :
Target Species: Human. Immunogen Description: Synthetic peptide from human TSC2.
other info2 :
Immunogen Type: Synthetic peptide. Immunogen: Tuberin / TSC2 antibody was raised against synthetic peptide from human TSC2. Antigen Modification: N-Terminus
products description :
Tuberous sclerosis complex (TSC) is an autosomal dominant tumor syndrome caused by mutations in either of the TSC1 or TSC2 tumor suppressor genes. The products of these genes form a protein complex that indirectly decreases the signaling of the mammalian Target of Rapamycin (TOR), an evolutionarily conserved serine/threonine kinase that regulates cell growth and cell cycle through its ability to integrate signals from nutrient levels and growth factors.
ncbi gi num :
116256352
ncbi acc num :
NP_000539.2
ncbi gb acc num :
NM_000548.3
uniprot acc num :
P49815
ncbi mol weight :
25,773 Da
ncbi pathways :
AKT Phosphorylates Targets In The Cytosol Pathway 106475!!AMPK Signaling Pathway 198868!!AMPK Signaling Pathway 989139!!AMPK Signaling Pathway 992181!!Adaptive Immune System Pathway 366160!!BDNF Signaling Pathway 712093!!Choline Metabolism In Cancer Pathway 1059539!!Choline Metabolism In Cancer Pathway 1084232!!Constitutive PI3K/AKT Signaling In Cancer Pathway 685535!!DAP12 Interactions Pathway 685549
ncbi summary :
Mutations in this gene lead to tuberous sclerosis complex. Its gene product is believed to be a tumor suppressor and is able to stimulate specific GTPases. The protein associates with hamartin in a cytosolic complex, possibly acting as a chaperone for hamartin. Alternative splicing results in multiple transcript variants encoding different isoforms. [provided by RefSeq, Jul 2008]
size :
0.05 mg
price :
495 USD
company information
MyBioSource
P.O. Box 153308
San Diego, CA 92195-3308
sales@mybiosource.com
https://www.mybiosource.com
1-888-627-0165
headquarters: USA
MyBioSource, LLC was orginally founded in Vancouver by three enthusiastic scientists who are passionate about providing the world with the best reagents available. Together, they form a company with a big vision known as MyBioSource. MyBioSource is now located in San Diego, California, USA.

"MyBioSource's number 1 vision is to be the world's number 1 quality reagents provider."

Our goal is to provide researchers, scientists and customers alike with a one-stop-shop for all of their reagents needs, whether it is monoclonal antibody, polyclonal antibody, recombinant protein, peptide, etc...

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