Rabbit Polyclonal to Mouse DLL1 | MyBioSource MBS240224 product information

product summary

company name :

MyBioSource

product type :

antibody

product name :

Rabbit Polyclonal to Mouse DLL1

catalog :

MBS240224

quantity :

0.05 mg

price :

495 USD

clonality :

polyclonal

host :

rabbit

conjugate :

nonconjugated

reactivity :

human, mouse, rat, chicken

application :

ELISA, immunohistochemistry, enzyme immunoassay

more info or order :

MyBioSource product webpage

product information

catalog number :

MBS240224

products type :

Antibody

products full name :

Rabbit Polyclonal to Mouse DLL1

products short name :

DLL1

products name syn :

Anti-DLL1 Antibody (aa155-173) IHC-plus; DLL1; Delta-like 1 (Drosophila); Delta (Drosophila)-like 1; Drosophila Delta homolog 1; Delta-like protein 1; Delta1; H-Delta-1; DL1; Npa; Mouse DLL1

other names :

delta-like protein 1; Delta-like protein 1; delta-like protein 1; H-Delta-1; drosophila Delta homolog 1; delta-like 1 (Drosophila); Drosophila Delta homolog 1; Delta1; H-Delta-1

products gene name :

DLL1

other gene names :

DLL1; DLL1; DL1; Delta; DELTA1; Delta1; H-Delta-1

uniprot entry name :

DLL1_HUMAN

clonality :

Polyclonal

host :

Rabbit

reactivity :

Chicken, Human, Mouse, Rat

sequence length :

723

specificity :

Amino acids 155-173 of Mouse DELTA-1. DELTA-1 is a mouse homolog of the Notch Delta ligand and is a member of the delta/serrate/jagged family. It plays a role in mediating cell fate decisions during hematopoiesis. It may play a role in cell-to-cell communication.

purity :

Immunoaffinity Purified

form :

0.02 M potassium phosphate, 0.15 M sodium chloride, pH 7.2, 0.01% sodium azide.

concentration :

1 mg/ml

storage stability :

+4 degree C or -20 degree C, Avoid repeated freezing and thawing.

tested application :

Immunohistochemistry (IHC - Paraffin), ELISA (EIA)

app notes :

ELISA, IHC-P (10 ug/ml). Usage: Immunohistochemistry: was validated for use in immunohistochemistry on a panel of 21 formalin-fixed, paraffin-embedded (FFPE) human tissues after heat induced antigen retrieval in pH 6.0 citrate buffer. After incubation with the primary antibo.

other info1 :

Target Species: Mouse. Immunogen Description: Synthetic peptide from mouse DLL1.

other info2 :

Immunogen Type: Synthetic peptide. Immunogen: DLL1 antibody was raised against synthetic peptide from mouse DLL1. Antigen Modification: aa155-173

products description :

DLL1 is a human homolog of the Notch Delta ligand and is a member of the delta/serrate/jagged family. DLL1 plays a role in mediating cell fate decisions during hematopoiesis. It may play a role in cell-to-cell communication.

ncbi gi num :

110735443

ncbi acc num :

NP_005609.3

ncbi gb acc num :

NM_005618.3

uniprot acc num :

O00548

ncbi mol weight :

27,355 Da

ncbi pathways :

Activated NOTCH1 Transmits Signal To The Nucleus Pathway (576270); Constitutive Signaling By NOTCH1 HD Domain Mutants Pathway (771591); Constitutive Signaling By NOTCH1 HD+PEST Domain Mutants Pathway (771595); Constitutive Signaling By NOTCH1 PEST Domain Mutants Pathway (771593); Constitutive Signaling By NOTCH1 T(7;9)(NOTCH1:M1580_K2555) Translocation Mutant Pathway (771589); Delta-Notch Signaling Pathway (198879); Disease Pathway (530764); FBXW7 Mutants And NOTCH1 In Cancer Pathway (771596); NOTCH2 Activation And Transmission Of Signal To The Nucleus Pathway (771602); Neural Crest Differentiation Pathway (672460)

ncbi summary :

DLL1 is a human homolog of the Notch Delta ligand and is a member of the delta/serrate/jagged family. It plays a role in mediating cell fate decisions during hematopoiesis. It may play a role in cell-to-cell communication. [provided by RefSeq, Jul 2008]

uniprot summary :

DLL1: Acts as a ligand for Notch receptors. Blocks the differentiation of progenitor cells into the B-cell lineage while promoting the emergence of a population of cells with the characteristics of a T-cell/NK-cell precursor. Interacts with Notch receptors. Expressed in heart and pancreas, with lower expression in brain and muscle and almost no expression in placenta, lung, liver and kidney. Protein type: Cell development/differentiation; Motility/polarity/chemotaxis; Membrane protein, integral. Chromosomal Location of Human Ortholog: 6q27. Cellular Component: integral to plasma membrane; extracellular region; plasma membrane; cytoplasmic vesicle. Molecular Function: protein binding; calcium ion binding; Notch binding. Biological Process: regulation of cell adhesion; Notch signaling pathway; negative regulation of myeloid cell differentiation; negative regulation of interleukin-10 production; Notch receptor processing; cell fate determination; compartment specification; somite specification; cell-cell signaling; negative regulation of auditory receptor cell differentiation; hemopoiesis; positive regulation of transcription from RNA polymerase II promoter; heart looping; determination of left/right symmetry; cell differentiation; inner ear development; positive regulation of Notch signaling pathway

size1 :

0.05 mg

price1 :

495 USD

more info or order :

MyBioSource product webpage