This webpage contains legacy information. The product is either no longer available from the supplier or has been delisted at Labome.
product summary
company name :
MyBioSource
product type :
antibody
product name :
Rabbit Polyclonal to Human PLA2G3
catalog :
MBS240191
quantity :
0.05 mg
price :
495 USD
clonality :
polyclonal
host :
rabbit
conjugate :
nonconjugated
reactivity :
human, mouse, rat, dog
application :
immunohistochemistry, immunohistochemistry - paraffin section
product information
catalog number :
MBS240191
products type :
Antibody
products full name :
Rabbit Polyclonal to Human PLA2G3
products short name :
PLA2G3
products name syn :
Anti-PLA2G3 Antibody (Internal) IHC-plus; PLA2G3; GIII-SPLA2; Phospholipase A2; group III; SPLA2-III; GIII sPLA2; SPLA2III; Human PLA2G3
other names :
group 3 secretory phospholipase A2; Group 3 secretory phospholipase A2; group 3 secretory phospholipase A2; group III secreted phospholipase A2; phosphatidylcholine 2-acylhydrolase 3; phosphatidylcholine 2-acylhydrolase GIII; phospholipase A2, group III; Group III secretory phospholipase A2; GIII sPLA2; sPLA2-III; Phosphatidylcholine 2-acylhydrolase 3
products gene name :
PLA2G3
other gene names :
PLA2G3; PLA2G3; SPLA2III; sPLA2-III; GIII-SPLA2; GIII sPLA2; sPLA2-III
uniprot entry name :
PA2G3_HUMAN
clonality :
Polyclonal
host :
Rabbit
reactivity :
Gibbon, Gorilla, Human. Predicted Reactivity: Monkey, Mouse, Rat, Dog, Hamster (at least 90% immunogen sequence identity)
sequence length :
509
specificity :
Human PLA2G3. BLAST analysis of the peptide immunogen showed no homology with other human proteins.
purity :
Immunoaffinity Purified
form :
PBS, 0.1% sodium azide.
concentration :
1 mg/ml
storage stability :
Long term: -70 degree C; Short term: +4 degree C
tested application :
Immunohistochemistry (IHC - Paraffin)
app notes :
IHC-P (10 ug/ml). Usage: Immunohistochemistry: was validated for use in immunohistochemistry on a panel of 21 formalin-fixed, paraffin-embedded (FFPE) human tissues after heat induced antigen retrieval in pH 6.0 citrate buffer. After incubation with the primary anti.
other info1 :
Target Species: Human. Immunogen Description: Synthetic 16 amino acid peptide from internal region of human PLA2G3. Percent identity with other species by BLAST analysis: Human, Gorilla, Gibbon, Monkey (100%); Marmoset, Mouse, Rat, Dog, Hamster (94%); Elephant, Panda, Rabbit (88%).
other info2 :
Immunogen Type: Synthetic peptide. Immunogen: PLA2G3 antibody was raised against synthetic 16 amino acid peptide from internal region of human PLA2G3. Percent identity with other species by BLAST analysis: Human, Gorilla, Gibbon, Monkey (100%); Marmoset, Mouse, Rat, Dog, Hamster (94%); Elephant, Panda, Rabbit (88%); Bovine, Horse, Pig (81%). Antigen Modification: Internal
products categories :
Family: Phospholipase
products description :
Human group III secreted phospholipase A2 belongs to a superfamily of intracellular and secreted enzymes that catalyze the hydrolysis of glycerophospholipids at the sn-2 position to release fatty acids and lysophospholipids. Group III PLA2 enzymes were originally identified in invertebrates such as bees and scorpions. Human group III sPLA2 has been shown to be a calcium dependent enzyme.
ncbi gi num :
142976884
ncbi acc num :
NP_056530.2
ncbi gb acc num :
NM_015715.4
uniprot acc num :
Q9NZ20
ncbi mol weight :
57,167 Da
ncbi pathways :
Acyl Chain Remodelling Of PC Pathway 645321!!Acyl Chain Remodelling Of PE Pathway 645317!!Acyl Chain Remodelling Of PG Pathway 645328!!Arachidonic Acid Metabolism Pathway 82991!!Arachidonic Acid Metabolism Pathway 366!!Ether Lipid Metabolism Pathway 82990!!Ether Lipid Metabolism Pathway 365!!Fat Digestion And Absorption Pathway 194385!!Fat Digestion And Absorption Pathway 194324!!Glycerophospholipid Biosynthesis Pathway 645313
ncbi summary :
This gene encodes a protein that belongs to the secreted phospholipase A2 family, whose members include the bee venom enzyme. The encoded enzyme functions in lipid metabolism and catalyzes the calcium-dependent hydrolysis of the sn-2 acyl bond of phospholipids to release arachidonic acid and lysophospholipids. This enzyme acts as a negative regulator of ciliogenesis, and may play a role in cancer development by stimulating tumor cell growth and angiogenesis. This gene is associated with oxidative stress, and polymorphisms in this gene are linked to risk for Alzheimer's disease. [provided by RefSeq, Apr 2014]
size :
0.05 mg
price :
495 USD
company information
MyBioSource
P.O. Box 153308
San Diego, CA 92195-3308
sales@mybiosource.com
https://www.mybiosource.com
1-888-627-0165
headquarters: USA
MyBioSource, LLC was orginally founded in Vancouver by three enthusiastic scientists who are passionate about providing the world with the best reagents available. Together, they form a company with a big vision known as MyBioSource. MyBioSource is now located in San Diego, California, USA.

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