This webpage contains legacy information. The product is either no longer available from the supplier or has been delisted at Labome.
product summary
company name :
MyBioSource
product type :
antibody
product name :
Rabbit Polyclonal to Human INSR / Insulin Receptor
catalog :
MBS240180
quantity :
0.05 mg
price :
495 USD
clonality :
polyclonal
host :
rabbit
conjugate :
nonconjugated
reactivity :
human, rat, dog, cow
application :
immunohistochemistry, immunohistochemistry - paraffin section
product information
catalog number :
MBS240180
products type :
Antibody
products full name :
Rabbit Polyclonal to Human INSR / Insulin Receptor
products short name :
INSR / Insulin Receptor
products name syn :
Anti-INSR / Insulin Receptor Antibody (Internal) IHC-plus; INSR; CD220; ILP receptor; Insulin receptor; IR; HHF5; CD220 antigen; Human INSR; Insulin Receptor
other names :
insulin receptor isoform Long preproprotein; Insulin receptor; insulin receptor; IR; insulin receptor; CD_antigen: CD220Cleaved into the following 2 chains:Insulin receptor subunit alpha; Insulin receptor subunit beta
products gene name :
INSR
other gene names :
INSR; INSR; HHF5; CD220; IR
uniprot entry name :
INSR_HUMAN
clonality :
Polyclonal
host :
Rabbit
reactivity :
Gibbon, Gorilla, Human, Monkey. Predicted Reactivity: Mouse, Rat, Bovine, Dog (at least 90% immunogen sequence identity)
sequence length :
1382
specificity :
Human Insulin Receptor. BLAST analysis of the peptide immunogen showed no homology with other human proteins, except JARID2 (69%).
purity :
Immunoaffinity Purified
form :
PBS, 0.1% sodium azide.
concentration :
1 mg/ml
storage stability :
Long term: -70 degree C; Short term: +4 degree C
tested application :
Immunohistochemistry (IHC - Paraffin)
app notes :
IHC-P (10 ug/ml). Usage: Immunohistochemistry: was validated for use in immunohistochemistry on a panel of 21 formalin-fixed, paraffin-embedded (FFPE) human tissues after heat induced antigen retrieval in pH 6.0 citrate buffer. After incubation with the primary anti.
other info1 :
Target Species: Human. Immunogen Description: Synthetic 16 amino acid peptide from internal region of human Insulin Receptor. Percent identity with other species by BLAST analysis: Human, Gorilla, Gibbon, Monkey (100%); Mouse, Rat, Bovine, Dog, Elephant, Panda (94%); Bat, Horse, Pig (88%).
other info2 :
Immunogen Type: Synthetic peptide. Immunogen: INSR / Insulin Receptor antibody was raised against synthetic 16 amino acid peptide from internal region of human Insulin Receptor. Percent identity with other species by BLAST analysis: Human, Gorilla, Gibbon, Monkey (100%); Mouse, Rat, Bovine, Dog, Elephant, Panda (94%); Bat, Horse, Pig (88%); Marmoset (81%). Antigen Modification: Internal
products categories :
Family: Protein Kinase. Subfamily: Insulin receptor
products description :
INSR is an insulin receptor type protein kinase. Binding of insulin to INSR stimulates glucose uptake. Two insulin receptor mRNA transcripts resulting from alternative splicing of exon 11 in the receptor gene are expressed in a highly regulated tissue-specific fashion.
ncbi gi num :
119395736
ncbi acc num :
NP_000199.2
ncbi gb acc num :
NM_000208.2
uniprot acc num :
P06213
ncbi mol weight :
155,146 Da
ncbi pathways :
AGE/RAGE Pathway 698754!!AMPK Signaling Pathway 198868!!AMPK Signaling Pathway 989139!!AMPK Signaling Pathway 992181!!Adherens Junction Pathway 83070!!Adherens Junction Pathway 481!!Aldosterone-regulated Sodium Reabsorption Pathway 130626!!Aldosterone-regulated Sodium Reabsorption Pathway 130590!!DNA Damage Response (only ATM Dependent) Pathway 198827!!FoxO Signaling Pathway 921162
ncbi summary :
After removal of the precursor signal peptide, the insulin receptor precursor is post-translationally cleaved into two chains (alpha and beta) that are covalently linked. Binding of insulin to the insulin receptor (INSR) stimulates glucose uptake. Two transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Jul 2008]
size :
0.05 mg
price :
495 USD
company information
MyBioSource
P.O. Box 153308
San Diego, CA 92195-3308
sales@mybiosource.com
https://www.mybiosource.com
1-888-627-0165
headquarters: USA
MyBioSource, LLC was orginally founded in Vancouver by three enthusiastic scientists who are passionate about providing the world with the best reagents available. Together, they form a company with a big vision known as MyBioSource. MyBioSource is now located in San Diego, California, USA.

"MyBioSource's number 1 vision is to be the world's number 1 quality reagents provider."

Our goal is to provide researchers, scientists and customers alike with a one-stop-shop for all of their reagents needs, whether it is monoclonal antibody, polyclonal antibody, recombinant protein, peptide, etc...

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