This webpage contains legacy information. The product is either no longer available from the supplier or has been delisted at Labome.
product summary
company name :
MyBioSource
product type :
antibody
product name :
Rabbit Polyclonal to Human HTR7 / 5-HT7 Receptor
catalog :
MBS240099
quantity :
0.05 mg
price :
495 USD
clonality :
polyclonal
host :
rabbit
conjugate :
nonconjugated
reactivity :
human, rat, dog, cow
application :
immunohistochemistry, enzyme immunoassay
product information
catalog number :
MBS240099
products type :
Antibody
products full name :
Rabbit Polyclonal to Human HTR7 / 5-HT7 Receptor
products short name :
HTR7 / 5-HT7 Receptor
products name syn :
Anti-HTR7 / 5-HT7 Receptor Antibody (Cytoplasmic Domain) IHC-plus; HTR7; 5-HT7; 5-HT7 receptor; 5-HT-7; 5-hydroxytryptamine 7 receptor; 5HT7; 5-HT-X; 5-hydroxytryptamine receptor 7; 5HT7 Receptor; HT7; Serotonin 5-HT7 receptor; Serotonin receptor 7; Human HTR7; 5-HT7 Receptor
other names :
5-hydroxytryptamine receptor 7 isoform d; 5-hydroxytryptamine receptor 7; 5-hydroxytryptamine receptor 7; 5-HT-7; 5-HT-X; 5-hydroxytryptamine (serotonin) receptor 7 (adenylate cyclase-coupled); 5-hydroxytryptamine (serotonin) receptor 7, adenylate cyclase-coupled; 5-HT-X; Serotonin receptor 7
products gene name :
HTR7
other gene names :
HTR7; HTR7; 5-HT7; 5-HT-7; 5-HT7
uniprot entry name :
5HT7R_HUMAN
clonality :
Polyclonal
host :
Rabbit
reactivity :
Gibbon, Gorilla, Human. Predicted Reactivity: Monkey, Rat, Bovine, Dog, Guinea pig, Hamster, Horse, Pig (at least 90% immunogen sequence identity)
sequence length :
479
specificity :
Human 5HT7 Receptor. BLAST analysis of the peptide immunogen showed no homology with other human proteins.
purity :
Immunoaffinity Purified
form :
PBS, 0.1% sodium azide.
concentration :
1 mg/ml
storage stability :
Long term: -70 degree C; Short term: +4 degree C
tested application :
Immunohistochemistry (IHC - Paraffin), ELISA (EIA)
app notes :
ELISA, IHC-P (10 ug/ml). Usage: Immunohistochemistry: was validated for use in immunohistochemistry on a panel of 21 formalin-fixed, paraffin-embedded (FFPE) human tissues after heat induced antigen retrieval in pH 6.0 citrate buffer. After incubation with the primary antib.
other info1 :
Target Species: Human. Immunogen Description: Synthetic 19 amino acid peptide from 3rd cytoplasmic domain of human 5HT7 Receptor. Percent identity with other species by BLAST analysis: Human, Gorilla, Gibbon, Monkey (100%); Marmoset, Rat, Bovine, Dog, Hamster, Panda, Horse, Pig, Guinea pig (95%).
other info2 :
Immunogen Type: Synthetic peptide. Immunogen: HTR7 / 5-HT7 Receptor antibody was raised against synthetic 19 amino acid peptide from 3rd cytoplasmic domain of human 5HT7 Receptor. Percent identity with other species by BLAST analysis: Human, Gorilla, Gibbon, Monkey (100%); Marmoset, Rat, Bovine, Dog, Hamster, Panda, Horse, Pig, Guinea pig (95%); Mouse, Bat (89%); Opossum (84%). Antigen Modification: Cytoplasmic Domain
products categories :
Family: GPCR. Subfamily: Serotonin
products description :
5-HT7 Receptor (HTR7)is a serotonin receptor with several functions, including regulation of the circadian rhythm and mediation of smooth-muscle relaxation in the vasculature and GI tract. HTR7 has been implicated in depression, autistic, and other neuropsychiatric disorders. Three protein isoforms have been documented: isoform a: 445aa; isoform b: 432aa; isoform d: 479aa.
ncbi gi num :
10880129
ncbi acc num :
NP_062873.1
ncbi gb acc num :
NM_019859.3
uniprot acc num :
P34969
ncbi mol weight :
47,984 Da
ncbi pathways :
Amine Ligand-binding Receptors Pathway 106363!!Calcium Signaling Pathway 83050!!Calcium Signaling Pathway 459!!Class A/1 (Rhodopsin-like Receptors) Pathway 106357!!Defective ACTH Causes Obesity And Pro-opiomelanocortinin Deficiency (POMCD) Pathway 1127664!!Disease Pathway 530764!!G Alpha (s) Signalling Events Pathway 119549!!GPCR Downstream Signaling Pathway 119548!!GPCR Ligand Binding Pathway 161020!!GPCRs, Class A Rhodopsin-like Pathway 198886
ncbi summary :
The neurotransmitter, serotonin, is thought to play a role in various cognitive and behavioral functions. The serotonin receptor encoded by this gene belongs to the superfamily of G protein-coupled receptors and the gene is a candidate locus for involvement in autistic disorder and other neuropsychiatric disorders. Three splice variants have been identified which encode proteins that differ in the length of their carboxy terminal ends. [provided by RefSeq, Jul 2008]
size :
0.05 mg
price :
495 USD
company information
MyBioSource
P.O. Box 153308
San Diego, CA 92195-3308
sales@mybiosource.com
https://www.mybiosource.com
1-888-627-0165
headquarters: USA
MyBioSource, LLC was orginally founded in Vancouver by three enthusiastic scientists who are passionate about providing the world with the best reagents available. Together, they form a company with a big vision known as MyBioSource. MyBioSource is now located in San Diego, California, USA.

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