catalog number :
MBS240072
products full name :
Rabbit Polyclonal to Human VIPR1
products short name :
VIPR1 / RDC1
products name syn :
Anti-VIPR1 / RDC1 Antibody (N-Terminus) IHC-plus; VIPR1; HVR1; PACAP type II receptor; PACAP-R-2; Pvr2; RDC1; Vip receptor subtype 1; Vpac1 receptor; V1RG; VIP receptor 1; VIPR; VIRG; VPCAP1R; PACAP-R2; VAPC1; VIP and PACAP receptor 1; VPAC1R; Pacap receptor; type ii; Type II PACAP receptor; Human VIPR1
other names :
vasoactive intestinal polypeptide receptor 1 isoform 1; Vasoactive intestinal polypeptide receptor 1; vasoactive intestinal polypeptide receptor 1; VIP receptor, type I; PACAP type II receptor; VIP and PACAP receptor 1; pituitary adenylate cyclase activating polypeptide receptor, type II; vasoactive intestinal peptide receptor 1; Pituitary adenylate cyclase-activating polypeptide type II receptor; PACAP type II receptor; PACAP-R-2; PACAP-R2; VPAC1
products gene name :
VIPR1
products gene name syn :
RDC1
other gene names :
VIPR1; VIPR1; II; HVR1; RDC1; V1RG; VIPR; VIRG; VAPC1; VPAC1; VPAC1R; VIP-R-1; VPCAP1R; PACAP-R2; PACAP-R-2; VIP-R-1; PACAP type II receptor; PACAP-R-2; PACAP-R2
uniprot entry name :
VIPR1_HUMAN
reactivity :
Human. Predicted Reactivity: Gorilla, Gibbon, Monkey, Bovine (at least 90% immunogen sequence identity)
specificity :
Human VIP Receptor 1. BLAST analysis of the peptide immunogen showed no homology with other human proteins.
purity :
Immunoaffinity Purified
form :
PBS, 0.1% sodium azide.
concentration :
0.22 mg/ml
storage stability :
Long term: -70 degree C; Short term: +4 degree C
tested application :
Immunohistochemistry (IHC - Paraffin), ELISA (EIA)
app notes :
ELISA, IHC-P (20 ug/ml). Usage: Immunohistochemistry: was validated for use in immunohistochemistry on a panel of 21 formalin-fixed, paraffin-embedded (FFPE) human tissues after heat induced antigen retrieval in pH 6.0 citrate buffer. After incubation with the primary anti.
other info1 :
Target Species: Human. Immunogen Description: Synthetic 20 amino acid peptide from N-terminus of human VIP Receptor 1. Percent identity with other species by BLAST analysis: Human (100%); Gorilla, Gibbon, Monkey, Marmoset, Bovine (95%); Guinea pig (85%); Pig (80%).
other info2 :
Immunogen Type: Synthetic peptide. Immunogen: VIPR1 antibody was raised against synthetic 20 amino acid peptide from N-terminus of human VIP Receptor 1. Percent identity with other species by BLAST analysis: Human (100%); Gorilla, Gibbon, Monkey, Marmoset, Bovine (95%); Guinea pig (85%); Pig (80%). Antigen Modification: N-Terminus
products categories :
Family: GPCR. Subfamily: Vasoactive intestinal polypeptide
products description :
Vasoactive Intestinal Polypeptide Receptor 1 (VIPR1) is a member of the Vasoactive Intestinal Polypeptide subfamily. Vasoactive intestinal peptide (VIP) plays multiple roles in the nervous, endocrine, and immune systems as a neurotransmitter, a hormone, and a cytokine. VIPR1, a receptor for VIP, has been shown to expressed widely in normal tissues and is the predominant receptor subtype for VIP in cancers.
ncbi acc num :
NP_004615.2
ncbi gb acc num :
NM_004624.3
ncbi mol weight :
47,201 Da
ncbi pathways :
G Alpha (s) Signalling Events Pathway 119549!!GPCR Downstream Signaling Pathway 119548!!GPCRs, Class B Secretin-like Pathway 198781!!Glucocorticoid Receptor Regulatory Network Pathway 138014!!Neuroactive Ligand-receptor Interaction Pathway 83053!!Neuroactive Ligand-receptor Interaction Pathway 462!!SIDS Susceptibility Pathways 198901!!Signal Transduction Pathway 477114!!Signaling By GPCR Pathway 106356
ncbi summary :
This gene encodes a receptor for vasoactive intestinal peptide, a small neuropeptide. Vasoactive intestinal peptide is involved in smooth muscle relaxation, exocrine and endocrine secretion, and water and ion flux in lung and intestinal epithelia. Its actions are effected through integral membrane receptors associated with a guanine nucleotide binding protein which activates adenylate cyclase. Several transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Oct 2011]