Rabbit Polyclonal to Human INPP5J / PIB5PA | MyBioSource MBS240056 product information

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product summary

company name :

MyBioSource

product type :

antibody

product name :

Rabbit Polyclonal to Human INPP5J / PIB5PA

catalog :

MBS240056

quantity :

0.05 mg

price :

495 USD

clonality :

polyclonal

host :

rabbit

conjugate :

nonconjugated

reactivity :

human, mouse, rat, dog

application :

immunohistochemistry, immunohistochemistry - paraffin section

product information

catalog number :

MBS240056

products type :

Antibody

products full name :

Rabbit Polyclonal to Human INPP5J / PIB5PA

products short name :

INPP5J / PIB5PA

products name syn :

Anti-INPP5J / PIB5PA Antibody (Internal) IHC-plus; INPP5J; PIB5PA; INPP5; PIPP; Human INPP5J; PIB5PA

other names :

phosphatidylinositol 4,5-bisphosphate 5-phosphatase A isoform c; Phosphatidylinositol 4,5-bisphosphate 5-phosphatase A; phosphatidylinositol 4,5-bisphosphate 5-phosphatase A; inositol polyphosphate 5-phosphatase J; phosphatidylinositol (4,5) bisphosphate 5-phosphatase, A; inositol polyphosphate-5-phosphatase J; Inositol polyphosphate 5-phosphatase J

products gene name :

INPP5J

products gene name syn :

PIB5PA

other gene names :

INPP5J; INPP5J; PIPP; INPP5; PIB5PA; PIB5PA; PIPP

uniprot entry name :

PI5PA_HUMAN

clonality :

Polyclonal

host :

Rabbit

reactivity :

Gorilla, Horse, Human, Pig. Predicted Reactivity: Gibbon, Monkey, Mouse, Rat, Bovine, Dog, Hamster, Rabbit (at least 90% immunogen sequence identity)

sequence length :

638

specificity :

Human INPP5J / PIB5PA. BLAST analysis of the peptide immunogen showed no homology with other human proteins.

purity :

Immunoaffinity Purified

form :

PBS, 0.1% sodium azide.

concentration :

1 mg/ml

storage stability :

Long term: -70 degree C; Short term: +4 degree C

tested application :

Immunohistochemistry (IHC - Paraffin)

app notes :

IHC-P (10 - 15 ug/ml). Usage: Immunohistochemistry: was validated for use in immunohistochemistry on a panel of 21 formalin-fixed, paraffin-embedded (FFPE) human tissues after heat induced antigen retrieval in pH 6.0 citrate buffer. After incubation with the primary anti.

other info1 :

Target Species: Human. Immunogen Description: Synthetic 19 amino acid peptide from internal region of human INPP5J / PIB5PA. Percent identity with other species by BLAST analysis: Human, Gorilla, Monkey, Elephant, Horse, Pig (100%).

other info2 :

Immunogen Type: Synthetic peptide. Immunogen: INPP5J / PIB5PA antibody was raised against synthetic 19 amino acid peptide from internal region of human INPP5J / PIB5PA. Percent identity with other species by BLAST analysis: Human, Gorilla, Monkey, Elephant, Horse, Pig (100%); Gibbon, Marmoset, Mouse, Rat, Bovine, Dog, Hamster, Panda, Rabbit (95%); Bat, Platypus (89%). Antigen Modification: Internal

products categories :

Family: Inositol phosphatase

ncbi gi num :

50726960

ncbi acc num :

NP_001002837.1

ncbi gb acc num :

NM_001002837.2

uniprot acc num :

Q15735

ncbi mol weight :

70,239 Da

ncbi pathways :

1D-myo-inositol Hexakisphosphate Biosynthesis II (mammalian) Pathway (545332); 1D-myo-inositol Hexakisphosphate Biosynthesis II (mammalian) Pathway (138949); 3-phosphoinositide Degradation Pathway (545349); 3-phosphoinositide Degradation Pathway (139488); D-myo-inositol (1,3,4)-trisphosphate Biosynthesis Pathway (545328); D-myo-inositol (1,3,4)-trisphosphate Biosynthesis Pathway (138943); D-myo-inositol (1,4,5)-trisphosphate Degradation Pathway (545327); D-myo-inositol (1,4,5)-trisphosphate Degradation Pathway (138942); Inositol Phosphate Metabolism Pathway (82987); Inositol Phosphate Metabolism Pathway (730320)

uniprot summary :

PI5PA: Inositol 5-phosphatase, which converts inositol 1,4,5- trisphosphate to inositol 1,4-bisphosphate. Also converts phosphatidylinositol 4,5-bisphosphate to phosphatidylinositol 4- phosphate and inositol 1,3,4,5-tetrakisphosphate to inositol 1,3,4-trisphosphate in vitro. May be involved in modulation of the function of inositol and phosphatidylinositol polyphosphate- binding proteins that are present at membranes ruffles. Belongs to the inositol 1,4,5-trisphosphate 5- phosphatase type II family. 3 isoforms of the human protein are produced by alternative splicing. Protein type: Phosphatase (non-protein); EC 3.1.3.56; Carbohydrate Metabolism - inositol phosphate. Chromosomal Location of Human Ortholog: 22q12.2. Cellular Component: ruffle; growth cone; cytoplasm; plasma membrane; dendritic shaft; cytosol. Molecular Function: inositol-polyphosphate 5-phosphatase activity; SH3 domain binding. Biological Process: inositol phosphate metabolic process; phospholipid metabolic process; negative regulation of microtubule polymerization; phosphatidylinositol biosynthetic process; negative regulation of peptidyl-serine phosphorylation; phosphoinositide dephosphorylation

size1 :

0.05 mg

price1 :

495 USD