Rabbit Polyclonal to Human NR4A1 / NUR77 | MyBioSource MBS240028 product information

This webpage contains legacy information. The product is either no longer available from the supplier or has been delisted at Labome.

product summary

company name :

MyBioSource

product type :

antibody

product name :

Rabbit Polyclonal to Human NR4A1 / NUR77

catalog :

MBS240028

quantity :

0.05 mg

price :

495 USD

clonality :

polyclonal

host :

rabbit

conjugate :

nonconjugated

reactivity :

human, dog

application :

immunohistochemistry, immunohistochemistry - paraffin section

product information

catalog number :

MBS240028

products type :

Antibody

products full name :

Rabbit Polyclonal to Human NR4A1 / NUR77

products short name :

NR4A1 / NUR77

products name syn :

Anti-NR4A1 / NUR77 Antibody (Internal) IHC-plus; NR4A1; GFRP1; Early response protein NAK1; HMR; NGFIB; Orphan nuclear receptor TR3; Orphan receptor tr3; Steroid receptor TR3; TR3; NAK1; NGFI-B; NP10; Receptor NGFIB; Testicular receptor 3; TR3 orphan receptor; N10; NAK-1; NUR77; Human NR4A1; NUR77

other names :

nuclear receptor subfamily 4 group A member 1 isoform 1; Nuclear receptor subfamily 4 group A member 1; nuclear receptor subfamily 4 group A member 1; ST-59; hormone receptor; TR3 orphan receptor; steroid receptor TR3; testicular receptor 3; early response protein NAK1; orphan nuclear receptor HMR; orphan nuclear receptor TR3; nuclear hormone receptor NUR/77; growth factor-inducible nuclear protein N10; nerve growth factor IB nuclear receptor variant 1; nuclear receptor subfamily 4, group A, member 1; Early response protein NAK1; Nuclear hormone receptor NUR/77; Nur77; Orphan nuclear receptor HMR; Orphan nuclear receptor TR3; ST-59; Testicular receptor 3

products gene name :

NR4A1

products gene name syn :

NUR77

other gene names :

NR4A1; NR4A1; HMR; N10; TR3; NP10; GFRP1; NAK-1; NGFIB; NUR77; GFRP1; HMR; NAK1; Nur77

uniprot entry name :

NR4A1_HUMAN

clonality :

Polyclonal

host :

Rabbit

reactivity :

Gibbon, Horse, Human, Monkey, Orangutan. Predicted Reactivity: Gorilla, Bat, Dog (at least 90% immunogen sequence identity)

sequence length :

598

specificity :

Human NUR77. BLAST analysis of the peptide immunogen showed no homology with other human proteins.

purity :

Immunoaffinity Purified

form :

PBS, 0.1% sodium azide.

concentration :

1 mg/ml

storage stability :

Long term: -70 degree C; Short term: +4 degree C

tested application :

Immunohistochemistry (IHC - Paraffin)

app notes :

IHC-P (20 ug/ml). Usage: Immunohistochemistry: was validated for use in immunohistochemistry on a panel of 21 formalin-fixed, paraffin-embedded (FFPE) human tissues after heat induced antigen retrieval in pH 6.0 citrate buffer. After incubation with the primary anti.

other info1 :

Target Species: Human. Immunogen Description: Synthetic 17 amino acid peptide from internal region of human NUR77. Percent identity with other species by BLAST analysis: Human, Orangutan, Gibbon, Monkey, Horse (100%); Gorilla, Dog, Bat, Panda (94%); Marmoset, Bovine (88%); Mouse, Rat (82%).

other info2 :

Immunogen Type: Synthetic peptide. Immunogen: NR4A1 / NUR77 antibody was raised against synthetic 17 amino acid peptide from internal region of human NUR77. Percent identity with other species by BLAST analysis: Human, Orangutan, Gibbon, Monkey, Horse (100%); Gorilla, Dog, Bat, Panda (94%); Marmoset, Bovine (88%); Mouse, Rat (82%). Antigen Modification: Internal

products categories :

Family: NHR. Subfamily: NR4 Nerve growth factor-like

products description :

Nak1, a NR4 Nerve Growth Factor-Like receptor, has been shown to affect the hypothalamic-pituitary axis, neuronal differentiation, neuroendocrine regulation of adrenocortical function, and T-cell apoptosis. Nak1 also is known as nuclear receptor Tr3 and is similar to mouse Nur77 and rat NGFI-B. It is encoded by one of the immediate early genes (IEG) in response to nerve growth factor and other serum growth factors.

ncbi gi num :

21361342

ncbi acc num :

NP_002126.2

ncbi gb acc num :

NM_002135.4

uniprot acc num :

P22736

ncbi mol weight :

33,754 Da

ncbi pathways :

AKT Phosphorylates Targets In The Nucleus Pathway 106476!!Adaptive Immune System Pathway 366160!!Constitutive PI3K/AKT Signaling In Cancer Pathway 685535!!Corticotropin-releasing Hormone Pathway 920957!!DAP12 Interactions Pathway 685549!!DAP12 Signaling Pathway 685550!!Disease Pathway 530764!!Downstream Signal Transduction Pathway 106385!!Downstream Signaling Events Of B Cell Receptor (BCR) Pathway 576250!!Downstream Signaling Of Activated FGFR Pathway 160957

ncbi summary :

This gene encodes a member of the steroid-thyroid hormone-retinoid receptor superfamily. Expression is induced by phytohemagglutinin in human lymphocytes and by serum stimulation of arrested fibroblasts. The encoded protein acts as a nuclear transcription factor. Translocation of the protein from the nucleus to mitochondria induces apoptosis. Multiple transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Jan 2011]

size :

0.05 mg

price :

495 USD