This webpage contains legacy information. The product is either no longer available from the supplier or has been delisted at Labome.
product summary
company name :
MyBioSource
product type :
antibody
product name :
Rabbit Polyclonal to Human PYGL
catalog :
MBS240020
quantity :
0.05 mg
price :
495 USD
clonality :
polyclonal
host :
rabbit
conjugate :
nonconjugated
reactivity :
human, dog
application :
immunohistochemistry, immunohistochemistry - paraffin section
product information
catalog number :
MBS240020
products type :
Antibody
products full name :
Rabbit Polyclonal to Human PYGL
products short name :
PYGL
products name syn :
Anti-PYGL Antibody (Internal) IHC-plus; PYGL; GPLL; Phosphorylase; glycogen liver; Phosphorylase; glycogen; liver; GSD6; Human PYGL
other names :
glycogen phosphorylase, liver form isoform 1; Glycogen phosphorylase, liver form; glycogen phosphorylase, liver form; phosphorylase, glycogen, liver
products gene name :
PYGL
other gene names :
PYGL; PYGL; GSD6
uniprot entry name :
PYGL_HUMAN
clonality :
Polyclonal
host :
Rabbit
reactivity :
Dog, Gorilla, Human. Predicted Reactivity: Gibbon, Monkey (at least 90% immunogen sequence identity)
sequence length :
847
specificity :
Human PYGL. BLAST analysis of the peptide immunogen showed no homology with other human proteins.
purity :
Immunoaffinity Purified
form :
PBS, 0.1% sodium azide.
concentration :
1 mg/ml
storage stability :
Long term: -70 degree C; Short term: +4 degree C
tested application :
Immunohistochemistry (IHC - Paraffin)
app notes :
IHC-P (10 ug/ml). Usage: Immunohistochemistry: was validated for use in immunohistochemistry on a panel of 21 formalin-fixed, paraffin-embedded (FFPE) human tissues after heat induced antigen retrieval in pH 6.0 citrate buffer. After incubation with the primary anti.
other info1 :
Target Species: Human. Immunogen Description: Synthetic 10 amino acid peptide from internal region of human PYGL. Percent identity with other species by BLAST analysis: Human, Gorilla, Monkey, Dog (100%); Gibbon, Marmoset, Panda (90%); Mouse, Sheep, Hamster, Horse, Rabbit (80%).
other info2 :
Immunogen Type: Synthetic peptide. Immunogen: PYGL antibody was raised against synthetic 10 amino acid peptide from internal region of human PYGL. Percent identity with other species by BLAST analysis: Human, Gorilla, Monkey, Dog (100%); Gibbon, Marmoset, Panda (90%); Mouse, Sheep, Hamster, Horse, Rabbit (80%). Antigen Modification: Internal
ncbi gi num :
71037379
ncbi acc num :
NP_002854.3
ncbi gb acc num :
NM_002863.4
uniprot acc num :
P06737
ncbi mol weight :
93,134 Da
ncbi pathways :
Disease Pathway 530764!!Glucose Metabolism Pathway 106199!!Glycogen Metabolism Pathway 198856!!Glycogen Breakdown (glycogenolysis) Pathway 106212!!Glycogen Storage Diseases Pathway 1127581!!Insulin Signaling Pathway 83090!!Insulin Signaling Pathway 501!!Metabolic Pathways 132956!!Metabolism Pathway 477135!!Metabolism Of Carbohydrates Pathway 106196
ncbi summary :
This gene encodes a homodimeric protein that catalyses the cleavage of alpha-1,4-glucosidic bonds to release glucose-1-phosphate from liver glycogen stores. This protein switches from inactive phosphorylase B to active phosphorylase A by phosphorylation of serine residue 15. Activity of this enzyme is further regulated by multiple allosteric effectors and hormonal controls. Humans have three glycogen phosphorylase genes that encode distinct isozymes that are primarily expressed in liver, brain and muscle, respectively. The liver isozyme serves the glycemic demands of the body in general while the brain and muscle isozymes supply just those tissues. In glycogen storage disease type VI, also known as Hers disease, mutations in liver glycogen phosphorylase inhibit the conversion of glycogen to glucose and results in moderate hypoglycemia, mild ketosis, growth retardation and hepatomegaly. Alternative splicing results in multiple transcript variants encoding different isoforms.[provided by RefSeq, Feb 2011]
size :
0.05 mg
price :
495 USD
company information
MyBioSource
P.O. Box 153308
San Diego, CA 92195-3308
sales@mybiosource.com
https://www.mybiosource.com
1-888-627-0165
headquarters: USA
MyBioSource, LLC was orginally founded in Vancouver by three enthusiastic scientists who are passionate about providing the world with the best reagents available. Together, they form a company with a big vision known as MyBioSource. MyBioSource is now located in San Diego, California, USA.

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Our goal is to provide researchers, scientists and customers alike with a one-stop-shop for all of their reagents needs, whether it is monoclonal antibody, polyclonal antibody, recombinant protein, peptide, etc...

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