catalog number :
MBS238420
products full name :
NATIVE HUMAN IgG
products short name :
IgG
other names :
Ig gamma-3 chain C region; Ig gamma-3 chain C region; immunoglobulin heavy constant gamma 3 (G3m marker); HDC; Heavy chain disease protein
other gene names :
IGHG3; IGHG3; IgG3
uniprot entry name :
IGHG3_HUMAN
form :
Purified. Purified immunoglobulin from human serum - lyophilised
storage stability :
Prior to reconstitution store at 4 degree C or -20 degree C. Avoid repeated freezing and thawing as this may denature the protein. After reconstitution storage at 4 degree C is recommended. This product should be stored undiluted. Shelf Life: 12 months from date of reconstitution
tested application :
ELISA (EIA)
other info1 :
Reconstitution: Reconstitute with 5.0 ml PBS and mix well. Heating to 37 degree C may aid reconstitution. Following reconstitution, storage at +4 degree C and the addition of 0.09% sodium azide is recommended. Preparation: Purified IgG isolated from a single donor containing Bence Jones protein.
other info2 :
Buffer Solution: Phosphate buffered saline. Target Species: Human
ncbi mol weight :
41,287 Da
ncbi pathways :
Classical Antibody-mediated Complement Activation Pathway (106409); Complement Cascade Pathway (106405); Creation Of C4 And C2 Activators Pathway (106407); FCGR Activation Pathway (771578); Fcgamma Receptor (FCGR) Dependent Phagocytosis Pathway (771577); IL4-mediated Signaling Events Pathway (137933); Immune System Pathway (106386); Initial Triggering Of Complement Pathway (106406); Innate Immune System Pathway (106387); Regulation Of Actin Dynamics For Phagocytic Cup Formation Pathway (771579)
uniprot summary :
IGHG3: Dimer linked by 12 disulfide bonds; it has an extra interchain disulfide bond at position 7 in addition to the 11 normally present in the hinge region. Chromosomal Location of Human Ortholog: 14q32.33. Cellular Component: extracellular space; extracellular region. Molecular Function: antigen binding. Biological Process: retinal homeostasis; innate immune response; complement activation, classical pathway; complement activation