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MOUSE ANTI HUMAN CD45:FITC/CD14:RPE

MBS238062

50 Tests

515 USD

MBS238062

Dual Color Reagent

MOUSE ANTI HUMAN CD45:FITC/CD14:RPE

CD45/CD14

receptor-type tyrosine-protein phosphatase C isoform 1; Receptor-type tyrosine-protein phosphatase C; receptor-type tyrosine-protein phosphatase C; CD45 antigen; T200 glycoprotein; T200 leukocyte common antigen; protein tyrosine phosphatase, receptor type, c polypeptide; protein tyrosine phosphatase, receptor type, C; Leukocyte common antigen; L-CA; T200; CD_antigen: CD45

CD45

PTPRC; PTPRC; LCA; LY5; B220; CD45; L-CA; T200; CD45R; GP180; CD45; L-CA

PTPRC_HUMAN

FITC reagent: IgG2a (MOUSE) . RPE reagent: IgG2a (MOUSE) .

F10-89-4/UCHM1

Mouse

1306

F10-89-4 recognises the human leucocyte common antigen (CD45), which is expressed by all haematopoietic cells. In peripheral blood the antigen is expressed more strongly by lymphocytes than by granulocytes. Erythrocytes do not express CD45. UCHM1 recognises a 55kDa glycoprotein expressed on the surface of monocytes and macrophages, and belongs to the CD14 cluster. Weak expression of CD14 may be detected on peripheral blood granulocytes.

FITC/RPE. Dual Colour combination consisting of FITC conjugated and RPE conjugated monoclonal antibodies mixed in optimal ratio - lyophilised.

Prior to reconstitution store at 4 degree C. Following reconstitution store at 4 degree C. DO NOT FREEZE. This product should be stored undiluted. This product is photosensitive and should be protected from light. Should this product contain a precipitate we recommend microcentrifugation before use. Shelf Life: 12 months from date of reconstitution.

Flow cytometry (FC/FACS)

Flow Cytometry: Use 10ul of the suggested working dilution to label 106 cells in 100ul. Flow Cytometry: Maximum Dilution: Neat

Reconstitution: Reconstitute with 0.5 ml distilled water. Perservative Stabilisers: 0.09% Sodium Azide. 1% Bovine Serum Albumin. 5% Sucrose

Buffer Solution: Phosphate buffered saline. Target Species: Human

F10-89-4 recognises the human leucocyte common antigen (CD45), which is expressed by all haematopoietic cells. In peripheral blood the antigen is expressed more strongly by lymphocytes than by granulocytes. Erythrocytes do not express CD45. UCHM1 recognises a 55kDa glycoprotein expressed on the surface of monocytes and macrophages, and belongs to the CD14 cluster. Weak expression of CD14 may be detected on peripheral blood granulocytes.

392307007

NP_002829.3

NM_002838.4

130,898 Da

Adaptive Immune System Pathway 366160!!Axon Guidance Pathway 105688!!B Cell Receptor Signaling Pathway 198909!!BCR Signaling Pathway 138058!!CXCR4-mediated Signaling Events Pathway 137910!!Cell Adhesion Molecules (CAMs) Pathway 83069!!Cell Adhesion Molecules (CAMs) Pathway 480!!Developmental Biology Pathway 477129!!EPO Receptor Signaling Pathway 198882!!Fc Gamma R-mediated Phagocytosis Pathway 114228

The protein encoded by this gene is a member of the protein tyrosine phosphatase (PTP) family. PTPs are known to be signaling molecules that regulate a variety of cellular processes including cell growth, differentiation, mitosis, and oncogenic transformation. This PTP contains an extracellular domain, a single transmembrane segment and two tandem intracytoplasmic catalytic domains, and thus is classified as a receptor type PTP. This PTP has been shown to be an essential regulator of T- and B-cell antigen receptor signaling. It functions through either direct interaction with components of the antigen receptor complexes, or by activating various Src family kinases required for the antigen receptor signaling. This PTP also suppresses JAK kinases, and thus functions as a regulator of cytokine receptor signaling. Alternatively spliced transcripts variants of this gene, which encode distinct isoforms, have been reported. [provided by RefSeq, Jun 2012]

50 Tests

515 USD