catalog number :
MBS238034
products full name :
SYNTHETIC HUMAN GAPDH (aa278-289)
products short name :
GAPDH
other names :
glyceraldehyde-3-phosphate dehydrogenase isoform 2; Glyceraldehyde-3-phosphate dehydrogenase; glyceraldehyde-3-phosphate dehydrogenase; aging-associated gene 9 protein; epididymis secretory sperm binding protein Li 162eP; peptidyl-cysteine S-nitrosylase GAPDH; glyceraldehyde-3-phosphate dehydrogenase; Peptidyl-cysteine S-nitrosylase GAPDH (EC:2.6.99.-)
products gene name :
GAPDH
other gene names :
GAPDH; GAPDH; G3PD; GAPD; HEL-S-162eP; GAPD; GAPDH
uniprot entry name :
G3P_HUMAN
form :
Purified. Purified synthetic peptide - liquid
concentration :
Total protein concentration 1.0mg/ml
storage stability :
Store at -20 degree C only. Storage in frost-free freezers is not recommended. This product should be stored undiluted. Avoid repeated freezing and thawing as this may denature the protein. Shelf Life: 18 months from date of despatch.
tested application :
ELISA (EIA)
other info1 :
Preparation: Solid phase synthesis
other info2 :
Buffer Solution: Acetate salt. Target Species: Human
products description :
MBS238034 is a 12 amino acid peptide, HQVVSSDFNSDT, corresponding to residues 278-289 of human Glyceraldehyde-3-phosphate dehydrogenase (GAPDH), a cytoplasmic enzyme involved in glycolysis.
ncbi acc num :
NP_001243728.1
ncbi gb acc num :
NM_001256799.2
ncbi mol weight :
31,548 Da
ncbi pathways :
Alzheimer's Disease Pathway 83097!!Alzheimer's Disease Pathway 509!!Alzheimers Disease Pathway 672448!!Biosynthesis Of Amino Acids Pathway 790012!!Biosynthesis Of Amino Acids Pathway 795174!!Carbon Metabolism Pathway 814926!!Carbon Metabolism Pathway 817567!!Disease Pathway 530764!!Gluconeogenesis Pathway 106204!!Gluconeogenesis, Oxaloacetate = Fructose-6P Pathway 413342
ncbi summary :
This gene encodes a member of the glyceraldehyde-3-phosphate dehydrogenase protein family. The encoded protein has been identified as a moonlighting protein based on its ability to perform mechanistically distinct functions. The product of this gene catalyzes an important energy-yielding step in carbohydrate metabolism, the reversible oxidative phosphorylation of glyceraldehyde-3-phosphate in the presence of inorganic phosphate and nicotinamide adenine dinucleotide (NAD). The encoded protein has additionally been identified to have uracil DNA glycosylase activity in the nucleus. Also, this protein contains a peptide that has antimicrobial activity against E. coli, P. aeruginosa, and C. albicans. Studies of a similar protein in mouse have assigned a variety of additional functions including nitrosylation of nuclear proteins, the regulation of mRNA stability, and acting as a transferrin receptor on the cell surface of macrophage. Many pseudogenes similar to this locus are present in the human genome. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Nov 2014]