catalog number :
MBS235398
products full name :
SHEEP ANTI HUMAN GROWTH HORMONE RELEASING HORMONE
products short name :
GROWTH HORMONE RELEASING HORMONE
other names :
somatoliberin isoform 2 preproprotein; Somatoliberin; somatoliberin; growth hormone-releasing factor; growth hormone-releasing hormone; sermorelin; somatocrinin; somatorelin; growth hormone releasing hormone; Growth hormone-releasing factor; GRF; Growth hormone-releasing hormone; GHRH; Somatocrinin; Somatorelin; INN: Sermorelin
other gene names :
GHRH; GHRH; GRF; INN; GHRF; GHRF; GRF; GHRH
uniprot entry name :
SLIB_HUMAN
specificity :
This item recognizes Growth Hormone Releasing Hormone (GHRH), a 44 amino acid peptide hormone that is produced by the hypothalamus. The main role of GHRH is to stimulate Growth Hormone, but it has the additional function of promoting slow wave sleep.
form :
Serum. Serum - liquid
concentration :
IgG concentration 5.0 mg/ml
storage stability :
Store at 4 degree C or at -20 degree C if preferred. Storage in frost-free freezers is not recommended. This product should be stored undiluted. Avoid repeated freezing and thawing as this may denature the antibody. Should this product contain a precipitate we recommend microcentrifugation before use. Shelf Life: 12 months from date of despatch.
tested application :
ELISA (EIA), Radioimmunoassays (RIA)
other info1 :
Perservative Stabilisers: 0.09% Sodium Azide (NaN3)
other info2 :
Immunogen: Growth Hormone Releasing Hormone conjugated to Keyhole Limpet Hemocyanin. Antiserum Preparation: Antiserum to GHRH was raised by repeated immunisation of sheep with highly purified antigen. Target Species: Human
products description :
MBS235398 recognizes Growth Hormone Releasing Hormone (GHRH), a 44 amino acid peptide hormone that is produced by the hypothalamus. The main role of GHRH is to stimulate Growth Hormone, but it has the additional function of promoting slow wave sleep.
ncbi acc num :
NP_001171660.1
ncbi gb acc num :
NM_001184731.1
ncbi mol weight :
12,360 Da
ncbi pathways :
Class B/2 (Secretin Family Receptors) Pathway 106378!!Defective ACTH Causes Obesity And Pro-opiomelanocortinin Deficiency (POMCD) Pathway 1127664!!Disease Pathway 530764!!G Alpha (s) Signalling Events Pathway 119549!!GPCR Downstream Signaling Pathway 119548!!GPCR Ligand Binding Pathway 161020!!Glucagon-type Ligand Receptors Pathway 106380!!Metabolic Disorders Of Biological Oxidation Enzymes Pathway 1127637!!Signal Transduction Pathway 477114!!Signaling By GPCR Pathway 106356
ncbi summary :
The protein encoded by this gene belongs to the glucagon family and is a preproprotein that is produced in the hypothalamus. The preproprotein is cleaved to form a 44 aa factor, also called somatocrinin, that acts to stimulate growth hormone release from the pituitary. Variant receptors for somatocrinin have been found in several types of tumors, and antagonists of these receptors can inhibit the growth of the tumors. Defects in this gene are a cause of dwarfism, while hypersecretion of the encoded protein is a cause of gigantism. [provided by RefSeq, Jul 2008]