catalog number :
MBS232468
products type :
Recombinant Protein
products full name :
RECOMBINANT HUMAN DEFENSIN BETA 3
products short name :
DEFENSIN BETA 3
other names :
beta-defensin 103; Beta-defensin 103; beta-defensin 103; beta defensin 3; beta defensin-3; beta-defensin 3; defensin, beta 103; defensin, beta 3; defensin-like protein; defensin, beta 103A; Beta-defensin 3; BD-3; DEFB-3; HBD3; hBD-3; Defensin, beta 103; Defensin-like protein
other gene names :
DEFB103A; DEFB103A; BD-3; HBD3; HBP3; DEFB3; HBP-3; hBD-3; DEFB-3; DEFB103; BD3; DEFB103; DEFB3; BD-3; DEFB-3; HBD3; hBD-3
uniprot entry name :
D103A_HUMAN
purity :
>98% by SDS PAGE and HPLC analysis
form :
Purified recombinant protein - lyophilised
concentration :
Approximate Protein Concentration: 1.0 mg/ml after reconstitution
storage stability :
Prior to reconstitution store at 4 degree C. After reconstitution store at -20 degree C. Storage in frost-free freezers is not recommended. This product should be stored undiluted. Avoid repeated freezing and thawing as this may denature the antibody. Should this product contain a precipitate we recommend microcentrifugation before use. Shelf Life: 3 months from date of reconstitution.
tested application :
ELISA (EIA), Functional Assays (FN), Western Blot (WB)
app notes :
ELISA: Minimum Dilution: 0.2; Maximum Dilution: 0.4ng/well;. Western Blotting: Minimum Dilution: 1.5; Maximum Dilution: 3.0ng/lane
other info1 :
Reconstitution: Reconstitute with 20ul 10mM acetic acid. Care should be taken during reconstitution as the protein may appear as a film at the bottom of the vial. MyBioSource recommends that the vial is gently mixed after reconstitution. N.B. For long term storage, further dilutions may be made in buffer containing 0.1% bovine serum albumin (BSA). Preparation: Purified recombinant defensin beta 3 expressed in E Coli
other info2 :
Activity: Exhibits chemotactic activity on monocytes. Target Species: Human
products description :
Defensin beta 3 (BD-3) is a cationic non-haemolytic antimicrobial peptide and member of the beta-defensin family, highly expressed by skin and tonsils, which plays an important role in the innate immune response to potentially pathogenic microbes, including multiresistant S. aureus and vancomycin-resistant E. faecium.
ncbi acc num :
NP_001075020.1
ncbi gb acc num :
NM_001081551.3
ncbi mol weight :
5.1kD (45 amino acid residues)
ncbi pathways :
Beta Defensins Pathway 530759!!Defensins Pathway 530757!!Immune System Pathway 106386!!Innate Immune System Pathway 106387
ncbi summary :
Defensins form a family of microbicidal and cytotoxic peptides made by neutrophils. Members of the defensin family are highly similar in protein sequence. This gene encodes defensin, beta 103, an antibiotic peptide which is induced by bacteria and interferon gamma, and which displays antimicrobial activity against S. aureus, S. pyogenes, P. aeruginosa, E. coli, and C. albicans. [provided by RefSeq, Oct 2014]