catalog number :
MBS232465
products type :
Recombinant Protein
products full name :
RECOMBINANT MOUSE GM-CSF
products short name :
GM-CSF
other names :
granulocyte-macrophage colony-stimulating factor; Granulocyte-macrophage colony-stimulating factor; granulocyte-macrophage colony-stimulating factor; CSF; granulocyte-macrophage colony stimulating factor 2; put. GM-CSF; colony stimulating factor 2 (granulocyte-macrophage); Colony-stimulating factor; CSF
products gene name :
GM-CSF
other gene names :
Csf2; Csf2; Csfgm; GMCSF; Gm-CSf; MGI-IGM; Csfgm; GM-CSF; CSF
uniprot entry name :
CSF2_MOUSE
purity :
>98% by SDS PAGE and HPLC analysis
form :
Purified recombinant protein - lyophilised
concentration :
Approximate Protein Concentration: 0.1 mg/ml after reconstitution
storage stability :
Prior to reconstitution store at 4 degree C. Following reconstitution store at -20 degree C. This product should be stored undiluted. Storage in frost-free freezers is not recommended. Avoid repeated freezing and thawing as this may denature the protein. Should this product contain a precipitate we recommend microcentrifugation before use. Shelf Life: 3 months from date of reconstitution.
tested application :
ELISA (EIA), Functional Assays (FN), Western Blot (WB)
app notes :
ELISA: Minimum Dilution: 0.2; Maximum Dilution: 0.4ng/well;. Western Blotting: Minimum Dilution: 1.5; Maximum Dilution: 3.0ng/lane
other info1 :
Reconstitution: Reconstitute with 0.2ml distilled water. Care should be taken during reconstitution as the protein may appear as a film at the bottom of the vial. MyBioSource recommends that the vial is gently mixed after reconstitution. Preparation: Purified recombinant GM-CSF expressed in E Coli
other info2 :
Buffer Solution: 10mM Acetic Acid. Activity: The ED50 as determined by the dose-dependent stimulation of the proliferation of murine FDC-P1 cells is = 0.05 ng/ml, corresponding to a specific activity of = 2 x 107 units/mg. Target Species: Mouse
products description :
GM-CSF (granulocyte-macrophage colony-stimulating factor) is a haematopoietic growth factor which exists in both glycosylated and non-glycosylated biologically active forms, and stimulates the development of granulocytes, macrophages, early megakaryocytes and eosinophil progenitor cells. The ability of recombinant GM-CSF to increase haematopoietic cell recovery has become a focus area in the therapeutic treatment of patients following bone marrow transplantation.
ncbi acc num :
NP_034099.2
ncbi gb acc num :
NM_009969.4
ncbi mol weight :
Protein Molecular Weight: 14.2kDa (124 amino acid residues)
ncbi pathways :
Amoebiasis Pathway 167330!!Amoebiasis Pathway 167191!!Cytokine Signaling In Immune System Pathway 1110778!!Cytokine-cytokine Receptor Interaction Pathway 83248!!Cytokine-cytokine Receptor Interaction Pathway 460!!Cytokines And Inflammatory Response (BioCarta) Pathway 198283!!Fc Epsilon RI Signaling Pathway 83279!!Fc Epsilon RI Signaling Pathway 493!!G Beta:gamma Signalling Through PI3Kgamma Pathway 1110535!!G-protein Beta:gamma Signalling Pathway 1110534